Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ATM98_RS04125 Genome accession   NZ_CP013651
Coordinates   841946..842647 (-) Length   233 a.a.
NCBI ID   WP_048789362.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 836946..847647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS04100 (ATM98_04100) rnc 837608..838309 (-) 702 WP_061564204.1 ribonuclease III -
  ATM98_RS04105 (ATM98_04105) - 838723..838905 (-) 183 WP_061564205.1 hypothetical protein -
  ATM98_RS09795 - 839056..839187 (-) 132 WP_257721763.1 hypothetical protein -
  ATM98_RS04110 (ATM98_04110) - 839342..839704 (-) 363 WP_006596984.1 YbaN family protein -
  ATM98_RS04115 (ATM98_04115) vicX 839789..840598 (-) 810 WP_061564206.1 MBL fold metallo-hydrolase Regulator
  ATM98_RS04120 (ATM98_04120) micB 840607..841953 (-) 1347 WP_061564207.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ATM98_RS04125 (ATM98_04125) micA 841946..842647 (-) 702 WP_048789362.1 response regulator YycF Regulator
  ATM98_RS04130 (ATM98_04130) thrS 843030..844973 (-) 1944 WP_061564208.1 threonine--tRNA ligase -
  ATM98_RS04135 (ATM98_04135) - 845357..846679 (-) 1323 WP_061564209.1 glycosyltransferase family 4 protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26629.57 Da        Isoelectric Point: 4.7304

>NTDB_id=163403 ATM98_RS04125 WP_048789362.1 841946..842647(-) (micA) [Streptococcus sp. A12]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALAVFEAESPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRTELTVESQTESTSDSEIVIGDLKIIPDAFLAQKKGKELELTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=163403 ATM98_RS04125 WP_048789362.1 841946..842647(-) (micA) [Streptococcus sp. A12]
ATGAAGAAAATTCTTGTTGTAGATGATGAAAAGCCGATTTCGGATATTATAAAATTCAATATGGCCAAAGAAGGCTATGA
AGTCTTGACTGCCTTCGATGGGAAAGAAGCACTGGCTGTTTTCGAAGCTGAGAGCCCAGATATTTTGATCTTGGACCTCA
TGCTTCCTGAAATTGACGGCTTGGAAGTGGCGCGTACCATTCGGAAGACTAGTAATGTGCCGATTATTGTTCTTTCTGCA
AAAGATACAGAATTTGATAAGGTTATCGGTCTTGAAATTGGGGCGGATGACTATGTGACCAAGCCATTCTCAAATCGTGA
GCTGCAAGCGCGTGTCAAAGCCCTGTTGCGTCGGACAGAATTAACGGTAGAATCACAAACAGAGTCTACATCAGATTCGG
AGATTGTGATTGGGGATTTGAAAATCATTCCGGATGCCTTCCTTGCTCAGAAAAAGGGCAAAGAGCTTGAGTTGACCCAT
CGCGAATTTGAGTTGCTCTATCACTTGGCGACCCATGTAGGCCAAGTCATGACTCGTGAGCATTTACTGGAAACAGTCTG
GGGCTACGATTATTTTGGTGATGTTCGGACAGTGGACGTAACGATTCGACGTTTGCGTGAAAAAATCGAAGACATTCCAG
GTCGTCCGGAGTATATTTTAACGCGCCGTGGTGTCGGTTACTATATGAGAAACAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.687

100

0.807
  vicR Streptococcus mutans UA159

77.966

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

99.142

0.446
  covR Streptococcus salivarius strain HSISS4

41.048

98.283

0.403

Multiple sequence alignment