Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   A6L42_RS00345 Genome accession   NZ_CP016671
Coordinates   77533..77814 (+) Length   93 a.a.
NCBI ID   WP_002214428.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22783     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 72533..82814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L42_RS14895 - 73973..74593 (+) 621 WP_002258722.1 hypothetical protein -
  A6L42_RS00320 (A6L42_00320) - 74596..75531 (+) 936 WP_002258723.1 immunity 49 family protein -
  A6L42_RS13450 (A6L42_00330) - 76095..76298 (+) 204 WP_002261355.1 hypothetical protein -
  A6L42_RS00340 (A6L42_00340) - 76863..77321 (+) 459 WP_002214429.1 hypothetical protein -
  A6L42_RS13455 - 77320..77454 (+) 135 Protein_63 IS1595 family transposase -
  A6L42_RS00345 (A6L42_00345) comA 77533..77814 (+) 282 WP_002214428.1 ATP-binding cassette domain-containing protein Regulator
  A6L42_RS00350 (A6L42_00350) - 77841..79061 (-) 1221 WP_002224009.1 YihY family inner membrane protein -
  A6L42_RS14900 - 79216..79402 (+) 187 Protein_66 NAD(P)H-quinone oxidoreductase -
  A6L42_RS00360 (A6L42_00360) queC 79606..80265 (+) 660 WP_002217873.1 7-cyano-7-deazaguanine synthase QueC -
  A6L42_RS00365 (A6L42_00365) - 80293..80811 (+) 519 WP_002241180.1 DUF1543 domain-containing protein -
  A6L42_RS00370 (A6L42_00370) queD 80818..81240 (+) 423 WP_002214424.1 6-carboxytetrahydropterin synthase QueD -
  A6L42_RS00375 (A6L42_00375) - 81509..81880 (+) 372 WP_002255771.1 DUF1304 domain-containing protein -
  A6L42_RS00380 (A6L42_00380) - 81877..82515 (+) 639 WP_002258545.1 7-carboxy-7-deazaguanine synthase QueE -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10070.73 Da        Isoelectric Point: 6.7158

>NTDB_id=162869 A6L42_RS00345 WP_002214428.1 77533..77814(+) (comA) [Neisseria meningitidis strain M22783]
MIHEEISAMPMGYETLIGDMGSALSGGQKQRIVLARALYCEPKILFLDAATSHLDIANEKAVNANLNGLSIIKIMAAHRK
ETVESADRKMSLG

Nucleotide


Download         Length: 282 bp        

>NTDB_id=162869 A6L42_RS00345 WP_002214428.1 77533..77814(+) (comA) [Neisseria meningitidis strain M22783]
ATGATTCACGAAGAAATCTCCGCCATGCCTATGGGCTATGAAACCTTGATCGGCGATATGGGCAGCGCACTGTCAGGCGG
ACAAAAACAACGCATCGTATTGGCGCGGGCCTTATATTGCGAACCGAAAATCCTATTTTTAGATGCAGCGACCAGCCATT
TGGATATTGCCAATGAAAAAGCAGTCAATGCAAACTTGAATGGCTTGTCTATCATAAAAATTATGGCGGCACACAGAAAG
GAAACGGTGGAATCAGCAGATAGGAAAATGTCTTTAGGATAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(14-52)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

45.055

97.849

0.441
  comA/nlmT Streptococcus mutans UA159

45.977

93.548

0.43
  comA Streptococcus pneumoniae Rx1

43.956

97.849

0.43
  comA Streptococcus pneumoniae D39

43.956

97.849

0.43
  comA Streptococcus pneumoniae R6

43.956

97.849

0.43
  comA Streptococcus pneumoniae TIGR4

43.956

97.849

0.43
  comA Streptococcus mitis NCTC 12261

43.956

97.849

0.43
  comA Streptococcus gordonii str. Challis substr. CH1

42.857

97.849

0.419