Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   APQ13_RS07445 Genome accession   NZ_CP013237
Coordinates   1559222..1559803 (-) Length   193 a.a.
NCBI ID   WP_002263134.1    Uniprot ID   -
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1545745..1578280 1559222..1559803 within 0


Gene organization within MGE regions


Location: 1545745..1578280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS07385 (APQ13_07370) - 1545745..1546620 (-) 876 WP_002289616.1 Abi family protein -
  APQ13_RS10020 - 1546772..1546933 (-) 162 WP_002302001.1 type II toxin-antitoxin system RelE family toxin -
  APQ13_RS07395 (APQ13_07380) - 1547110..1547619 (-) 510 WP_002271555.1 HXXEE domain-containing protein -
  APQ13_RS07400 (APQ13_07385) - 1547787..1548329 (+) 543 WP_002270117.1 TetR/AcrR family transcriptional regulator -
  APQ13_RS07405 (APQ13_07390) purH 1548512..1550059 (-) 1548 WP_014834769.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
  APQ13_RS07410 (APQ13_07395) - 1550101..1550808 (-) 708 WP_002273391.1 suppressor of fused domain protein -
  APQ13_RS07415 (APQ13_07400) purN 1550915..1551469 (-) 555 WP_002267558.1 phosphoribosylglycinamide formyltransferase -
  APQ13_RS07420 (APQ13_07405) purM 1551469..1552491 (-) 1023 WP_002267557.1 phosphoribosylformylglycinamidine cyclo-ligase -
  APQ13_RS07425 (APQ13_07410) purF 1552550..1553989 (-) 1440 WP_002263130.1 amidophosphoribosyltransferase -
  APQ13_RS07430 (APQ13_07415) - 1554015..1554635 (-) 621 WP_002267556.1 DNA alkylation repair protein -
  APQ13_RS07435 (APQ13_07420) - 1554657..1558382 (-) 3726 WP_002267555.1 phosphoribosylformylglycinamidine synthase -
  APQ13_RS07440 (APQ13_07425) purC 1558392..1559099 (-) 708 WP_002263133.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  APQ13_RS07445 (APQ13_07430) comA 1559222..1559803 (-) 582 WP_002263134.1 ATP-binding cassette domain-containing protein Regulator
  APQ13_RS07450 (APQ13_07435) - 1560031..1560279 (-) 249 WP_002263135.1 acyl carrier protein -
  APQ13_RS07455 (APQ13_07440) plsX 1560281..1561279 (-) 999 WP_002263136.1 phosphate acyltransferase PlsX -
  APQ13_RS07460 (APQ13_07445) recO 1561487..1562242 (-) 756 WP_002263137.1 DNA repair protein RecO -
  APQ13_RS07465 (APQ13_07450) - 1562232..1563407 (-) 1176 WP_002273747.1 pyridoxal phosphate-dependent aminotransferase -
  APQ13_RS07470 (APQ13_07455) - 1563496..1564464 (-) 969 WP_002263139.1 ribose-phosphate diphosphokinase -
  APQ13_RS07475 (APQ13_07460) gbpB 1564589..1565884 (-) 1296 WP_002264119.1 glucan-binding protein GbpB -
  APQ13_RS07480 (APQ13_07465) mreD 1565994..1566500 (-) 507 WP_002263141.1 rod shape-determining protein MreD -
  APQ13_RS07485 (APQ13_07470) mreC 1566502..1567320 (-) 819 WP_002263142.1 rod shape-determining protein MreC -
  APQ13_RS07595 (APQ13_07580) - 1574408..1575823 (-) 1416 WP_002262635.1 APC family permease -
  APQ13_RS07600 (APQ13_07585) ftsH 1576310..1578280 (-) 1971 WP_002266494.1 ATP-dependent zinc metalloprotease FtsH -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21388.42 Da        Isoelectric Point: 4.8930

>NTDB_id=160995 APQ13_RS07445 WP_002263134.1 1559222..1559803(-) (comA) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MGKSGSGKTTLAKILAGYYTVSSGDSFLDGEKINYSQLRQLVTYVPQQSYVFTGTILDNLLLGAEEEVTDDRLMEVCSIA
EILDNIKAMPLGFQTQISEDGGLSGGQKQRLAIARALLTRQPVLIFDEATSGLDRDTEEKVIANLSKLERTIIFIAHRGS
VSYYADRIVEIDSGEKIKDRINHRPFSFLMMTL

Nucleotide


Download         Length: 582 bp        

>NTDB_id=160995 APQ13_RS07445 WP_002263134.1 1559222..1559803(-) (comA) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGGGGAAAAGTGGTTCTGGAAAGACAACTTTGGCAAAAATTCTTGCAGGCTATTATACTGTTAGTAGCGGTGACTCTTT
CTTAGATGGAGAAAAGATAAATTATTCCCAGCTGCGCCAATTAGTAACTTATGTGCCACAGCAGTCTTATGTTTTTACAG
GAACAATCTTAGATAATCTGCTTCTTGGTGCTGAAGAGGAAGTAACGGATGATCGCTTAATGGAAGTTTGTTCAATTGCT
GAAATTTTAGACAATATCAAGGCAATGCCTTTAGGTTTTCAAACACAGATTTCAGAAGACGGCGGTTTATCTGGTGGTCA
AAAACAGCGTTTAGCTATTGCACGTGCTCTCTTAACCAGACAGCCTGTGTTGATTTTTGATGAGGCAACTAGTGGTTTAG
ATCGTGATACCGAAGAAAAAGTTATTGCCAATTTATCTAAATTGGAGCGCACGATTATTTTTATTGCTCACCGAGGCAGT
GTTTCTTATTATGCTGATCGAATTGTTGAGATTGACTCTGGAGAGAAAATTAAGGATAGAATAAATCATCGTCCTTTCTC
ATTTTTGATGATGACTCTTTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

50.802

96.891

0.492
  comA Streptococcus gordonii str. Challis substr. CH1

51.099

94.301

0.482
  comA/nlmT Streptococcus mutans UA159

49.468

97.409

0.482
  comA Streptococcus pneumoniae D39

49.18

94.819

0.466
  comA Streptococcus pneumoniae Rx1

49.18

94.819

0.466
  comA Streptococcus pneumoniae R6

49.18

94.819

0.466
  comA Streptococcus mitis SK321

48.087

94.819

0.456
  comA Streptococcus pneumoniae TIGR4

48.087

94.819

0.456

Multiple sequence alignment