Detailed information NTG0160715

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HSISS4_RS07510
• Genome accession: NZ_CP013216
• Coordinates: 1661957..1664197 (-)
• Length: 746 a.a.
• NCBI ID: WP_021143744.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain HSISS4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1656957..1669197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSISS4_RS07490 (HSISS4_01462)	-	1657821..1658681 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
HSISS4_RS07495 (HSISS4_01463)	spxR	1658725..1660005 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
HSISS4_RS07500 (HSISS4_01464)	-	1659998..1660543 (-)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
HSISS4_RS07505 (HSISS4_01465)	-	1660609..1661871 (-)	1263	WP_021143745.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HSISS4_RS07510 (HSISS4_01466)	comEC/celB	1661957..1664197 (-)	2241	WP_021143744.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HSISS4_RS07515 (HSISS4_01467)	comEA	1664187..1664882 (-)	696	WP_021143743.1	helix-hairpin-helix domain-containing protein	Machinery gene
HSISS4_RS07520 (HSISS4_01468)	-	1664990..1665745 (-)	756	WP_021143742.1	lysophospholipid acyltransferase family protein	-
HSISS4_RS07525 (HSISS4_01469)	-	1665874..1666809 (+)	936	WP_021143741.1	polysaccharide deacetylase family protein	-
HSISS4_RS07530 (HSISS4_01470)	-	1666859..1667623 (+)	765	WP_059749235.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
HSISS4_RS07535 (HSISS4_01471)	-	1667627..1667896 (+)	270	WP_021143739.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84596.50 Da
• Isoelectric Point: 9.9132

>NTDB_id=160715 HSISS4_RS07510 WP_021143744.1 1661957..1664197(-) (comEC/celB) [Streptococcus salivarius strain HSISS4]
MWLKKAPISLFSLSLLIAALYFTIFVTNVYAIGTFVFLMVCFLKHHWKNKAALKLVGLVGSFFLIYFLFLQHRATIQDKQ
APTAINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQYFFKTTSQTLVLKGKINLSPVTGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVSQKNTSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLMFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFVLSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVLLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGLKEKWQEASQTSNAEKTLIPYLQARGVSQIDHMVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPNLKAGILKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLKRFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=160715 HSISS4_RS07510 WP_021143744.1 1661957..1664197(-) (comEC/celB) [Streptococcus salivarius strain HSISS4]
ATGTGGCTTAAAAAAGCGCCAATCAGTCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATTGGAACTTTTGTCTTTCTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTAGTTTCTTTTTGATTTACTTTTTATTCTTGCAACACAGAGCTACCATACAAGATAAACAA
GCTCCTACTGCAATCAATCAAGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACCTATCAGGTTTTTTACCGACTCAAATCTGAGAAGGAGCAGTATTTTTTTAAGACTACTAGTCAAA
CCTTGGTATTAAAAGGGAAAATAAACTTATCCCCAGTAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAGCGCTTGGATCATGTGGTGTCTCAAAAAAACACATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATTCAGACGCATTTTCCTAATCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCTGTCCTACGTTCCT
TGATTCAAAGTTTGTTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTAATGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACAGCGATGTTTTCGATAGTCTTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGTCCTTTCAGGGTTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTCTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTCTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTGATTGATGTGGGTGGCAAGGTGACTTTCGGCCTAAAGGAAAAATGGCAAGAGGCTAGTCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATATGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTAGGACTTTAAAACGCCCAGTTCGTACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGCAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAATAATGATTCGATAGTGCTCTATGGAAAATTA
TTAGGAAGCAGTTTTCTGTTTACGGGTGATCTGGAAAAGGAAGGAGAGGAGGAACTGATGGCCAGTTATCCCAATTTAAA
AGCAGGCATCCTCAAAGCTGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGCTATAAACATCCAAATGATGAAACTTTGAAGCGTTTTAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAAGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.465	100	0.487
comEC/celB	Streptococcus mitis SK321	48.133	100	0.484
comEC/celB	Streptococcus pneumoniae R6	47.333	100	0.476
comEC/celB	Streptococcus pneumoniae D39	47.333	100	0.476
comEC/celB	Streptococcus pneumoniae Rx1	47.333	100	0.476
comEC/celB	Streptococcus pneumoniae TIGR4	47.2	100	0.475
comEC	Lactococcus lactis subsp. cremoris KW2	42.973	99.196	0.426