Detailed information NTG0159985

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: AQ622_RS25195
• Genome accession: NZ_CP013113
• Coordinates: 5300723..5302060 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain Paer4_119
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5295723..5307060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AQ622_RS25170 (AQ622_04873)	pgeF	5295866..5296594 (-)	729	WP_003123393.1	peptidoglycan editing factor PgeF	-
AQ622_RS25175 (AQ622_04874)	rluD	5296591..5297553 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
AQ622_RS25180 (AQ622_04875)	-	5297699..5298724 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
AQ622_RS25185 (AQ622_04876)	-	5298881..5299126 (+)	246	WP_009316269.1	PP0621 family protein	-
AQ622_RS25190 (AQ622_04877)	pilS	5299116..5300708 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
AQ622_RS25195 (AQ622_04878)	pilR	5300723..5302060 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
AQ622_RS25200 (AQ622_04879)	thiO	5302106..5303200 (-)	1095	WP_003123395.1	glycine oxidase ThiO	-
AQ622_RS25205 (AQ622_04880)	-	5303335..5303844 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
AQ622_RS25210 (AQ622_04881)	-	5303950..5304456 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
AQ622_RS25215 (AQ622_04882)	pilV	5304447..5305004 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
AQ622_RS25220 (AQ622_04883)	pilW	5305001..5305825 (+)	825	WP_003123396.1	type 4a pilus minor pilin PilW	-
AQ622_RS25225 (AQ622_04884)	pilX	5305822..5306409 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=159985 AQ622_RS25195 WP_003094694.1 5300723..5302060(+) (pilR) [Pseudomonas aeruginosa strain Paer4_119]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=159985 AQ622_RS25195 WP_003094694.1 5300723..5302060(+) (pilR) [Pseudomonas aeruginosa strain Paer4_119]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384