Detailed information NTG0158612

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: ACT75_RS07355
• Genome accession: NZ_CP012959
• Coordinates: 1508765..1509988 (-)
• Length: 407 a.a.
• NCBI ID: WP_061866560.1
• Uniprot ID: -
• Organism: Aggregatibacter actinomycetemcomitans strain 624
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1503765..1514988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACT75_RS07335 (ACT75_07325)	-	1504431..1506551 (-)	2121	WP_005539198.1	alpha/beta hydrolase	-
ACT75_RS07340 (ACT75_07330)	-	1506574..1507701 (-)	1128	WP_005539200.1	DUF4123 domain-containing protein	-
ACT75_RS07350 (ACT75_07340)	-	1508079..1508768 (-)	690	WP_005594882.1	prepilin peptidase	-
ACT75_RS07355 (ACT75_07345)	pilC	1508765..1509988 (-)	1224	WP_061866560.1	type II secretion system F family protein	Machinery gene
ACT75_RS07360 (ACT75_07350)	pilB	1509981..1511390 (-)	1410	WP_005540457.1	GspE/PulE family protein	Machinery gene
ACT75_RS07365 (ACT75_07355)	pilA	1511417..1511869 (-)	453	WP_005550263.1	pilin	Machinery gene
ACT75_RS07370 (ACT75_07360)	ampD	1511991..1512545 (+)	555	WP_005540460.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
ACT75_RS07375 (ACT75_07365)	nanQ	1513011..1513484 (-)	474	WP_005594879.1	N-acetylneuraminate anomerase	-

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 46195.68 Da
• Isoelectric Point: 10.3517

>NTDB_id=158612 ACT75_RS07355 WP_061866560.1 1508765..1509988(-) (pilC) [Aggregatibacter actinomycetemcomitans strain 624]
MTKLKLFQWRGVNRLQQKQKGLIVAETEVMAQQQLLSRGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLRAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDSSNAQLPVFTQVLLALSQGLQDYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSRSLFLMLQAGIPLNQALQSFLPKQQSWQSKPQQQGDWLLITEVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide

• Length: 1224 bp

>NTDB_id=158612 ACT75_RS07355 WP_061866560.1 1508765..1509988(-) (pilC) [Aggregatibacter actinomycetemcomitans strain 624]
ATGACTAAATTGAAACTGTTTCAATGGCGCGGCGTTAATCGCTTGCAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGTGATGGCACAACAACAGCTGCTTTCACGTGGGTTGCAAAACATCAAATTGCAACAAAACTGGCAATTCAGCCACA
AACCGAAAAATGCCGACATCTGCACCCTGCTTTCCCAACTGGCGACGCTATTACGAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTGGCATTTTCTCAAGCATTGGAACAACAAGGGTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTCTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAGCAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGATTATTGGTTCGCGCTACTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGTTGCTTAATCGTATCGTACAACTCTCCCGCCTGGTGGGATT
CAGTCGCAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTGCAATCTTTTCTACCGAAGCAACAAA
GCTGGCAAAGCAAACCGCAACAGCAAGGGGATTGGCTATTAATTACAGAAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAGCAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAGTTGGATCACCAAATCGATCTGCTGTCAC
AAATGCTGGAACCGTTGTTGATGGTGATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTGCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (267-398)

• Type II secretion system (T2SS), protein F (T2SSF) (64-186)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae Rd KW20	63.145	100	0.631
pilC	Haemophilus influenzae 86-028NP	62.899	100	0.629
pilC	Glaesserella parasuis strain SC1401	39.312	100	0.393