Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACT74_RS08620 Genome accession   NZ_CP012958
Coordinates   1794215..1795624 (-) Length   469 a.a.
NCBI ID   WP_050846294.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain VT1169     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1789215..1800624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT74_RS08600 (ACT74_08600) - 1789771..1790775 (-) 1005 WP_061869981.1 hypothetical protein -
  ACT74_RS08605 (ACT74_08605) - 1791505..1792359 (-) 855 WP_005544984.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  ACT74_RS08610 (ACT74_08610) aroB 1792362..1793450 (-) 1089 WP_005569125.1 3-dehydroquinate synthase -
  ACT74_RS08615 (ACT74_08615) aroK 1793474..1794001 (-) 528 WP_005555432.1 shikimate kinase AroK -
  ACT74_RS08620 (ACT74_08620) comE 1794215..1795624 (-) 1410 WP_050846294.1 type IV pilus secretin PilQ Machinery gene
  ACT74_RS08625 (ACT74_08625) - 1795644..1796036 (-) 393 WP_005544975.1 hypothetical protein -
  ACT74_RS08630 (ACT74_08630) - 1796036..1796560 (-) 525 WP_005543969.1 hypothetical protein -
  ACT74_RS08635 (ACT74_08635) - 1796557..1797075 (-) 519 WP_005544973.1 PilN domain-containing protein -
  ACT74_RS08640 (ACT74_08640) - 1797086..1797895 (-) 810 WP_005544971.1 hypothetical protein -
  ACT74_RS08645 (ACT74_08645) - 1798029..1800596 (+) 2568 WP_005566815.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 469 a.a.        Molecular weight: 51720.35 Da        Isoelectric Point: 7.1242

>NTDB_id=158587 ACT74_RS08620 WP_050846294.1 1794215..1795624(-) (comE) [Aggregatibacter actinomycetemcomitans strain VT1169]
MKSILSRRLKCGLFFGCFLSLAVQAEQNPVFSIRLKQAPLVPTLQQLALAHNTNLIIDDELQGTVSLQLENVDLDQLFRS
VAKIKQLDLWQENGIYYFTKGDTNTKFAGKMEEPFPLSLPMAEEPAQLNTATIKLHFAKASEVMKSLTGGSGSLLSPNGS
ITFDDRSNLLLIQDEPRSVRNIKKLINELDKPIEQIAIEARIVTINDESLKELGVRWGIFSPTDNAHRIGGSLAGNGFDN
LVNQLNVNFPTTTTPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTELPYILVNEKSGSQ
SVEFREAVLGLEVTPHISQDKQILLDLIVSQNSPGSRVAYGLGEVVSIDKQEINTQVFAKDGETIVLGGVFSDTITKGTD
KVPVLGDIPGIKHLFSKESERHQKRELVIFVTPHILRKGETPDAFKQKRIGVNEQIMAKGENKKDLNRK

Nucleotide


Download         Length: 1410 bp        

>NTDB_id=158587 ACT74_RS08620 WP_050846294.1 1794215..1795624(-) (comE) [Aggregatibacter actinomycetemcomitans strain VT1169]
ATGAAATCGATCCTTTCCCGACGACTAAAGTGCGGTCTGTTTTTCGGGTGTTTTTTAAGTCTTGCGGTGCAGGCGGAACA
AAATCCGGTGTTTTCCATTCGGCTGAAACAGGCACCACTGGTTCCGACTTTGCAGCAGTTGGCATTAGCCCACAATACCA
ATTTGATTATTGACGATGAACTGCAAGGCACGGTGTCGTTACAGTTGGAAAACGTGGATTTGGATCAGCTGTTTCGTTCT
GTGGCAAAAATTAAACAACTGGATTTATGGCAGGAAAACGGCATTTATTATTTCACTAAAGGCGACACCAACACGAAATT
TGCCGGCAAAATGGAAGAGCCTTTCCCTCTTTCTCTGCCCATGGCGGAAGAACCGGCACAGCTGAACACGGCGACCATTA
AATTACACTTTGCCAAAGCGTCGGAAGTGATGAAATCCCTCACCGGGGGGAGTGGTTCCCTGTTGTCGCCTAACGGCAGT
ATCACTTTCGACGATCGTAGCAATTTGTTGCTGATTCAGGATGAACCGCGCTCCGTCCGCAACATAAAAAAGCTGATTAA
TGAACTGGATAAACCCATTGAGCAAATCGCCATTGAAGCGCGCATTGTCACCATTAACGATGAAAGCCTGAAAGAACTGG
GCGTGCGCTGGGGCATTTTCAGCCCGACGGACAACGCCCATCGTATCGGTGGCAGTTTGGCGGGCAACGGCTTTGATAAC
CTTGTCAATCAGTTAAACGTAAATTTTCCCACGACCACGACACCGGCAGGCTCTGTGGCGTTACAGGTTGCGAAAATCAA
CGGGCGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATGTGGAAATCATCGCAAGCCCACGCCTGCTAA
CGACAAACAAAAAAAGCGCCAGCATCAAACAGGGGACGGAATTGCCCTATATTCTGGTGAACGAAAAAAGCGGTTCGCAA
AGCGTGGAATTTCGTGAGGCGGTACTAGGTTTGGAAGTCACGCCGCACATTTCGCAGGATAAACAAATTCTGTTAGATCT
TATCGTCAGCCAAAACTCGCCGGGCAGCCGTGTGGCGTACGGTTTGGGCGAAGTGGTTTCTATTGATAAACAGGAGATTA
ATACACAAGTCTTCGCCAAGGACGGCGAAACCATTGTGCTGGGCGGTGTATTTAGCGATACCATCACCAAAGGCACCGAT
AAAGTGCCGGTGCTGGGTGACATTCCGGGTATTAAACATTTATTCAGCAAGGAAAGTGAACGCCATCAAAAACGCGAGCT
GGTGATTTTTGTCACACCACATATTTTGCGTAAAGGCGAAACCCCGGACGCTTTCAAACAAAAGCGAATCGGGGTAAATG
AGCAAATCATGGCAAAAGGGGAGAATAAAAAGGACCTAAATAGGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(277-437)

Bacterial type II/III secretion system short domain (Secretin_N)

(130-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

71.812

95.309

0.684
  comE Haemophilus influenzae 86-028NP

70.917

95.309

0.676
  comE Glaesserella parasuis strain SC1401

52.86

93.177

0.493
  pilQ Vibrio campbellii strain DS40M4

41.244

92.537

0.382
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.822

91.258

0.382
  pilQ Vibrio cholerae strain A1552

41.822

91.258

0.382

Multiple sequence alignment