Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   UW163_RS12235 Genome accession   NZ_CP012939
Coordinates   2624108..2626648 (+) Length   846 a.a.
NCBI ID   WP_014617396.1    Uniprot ID   F6G2D6
Organism   Ralstonia solanacearum strain UW163     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2619108..2631648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UW163_RS12215 (UW163_12205) - 2620125..2621204 (-) 1080 WP_014617400.1 hypothetical protein -
  UW163_RS12220 (UW163_12210) - 2621277..2622527 (+) 1251 WP_003268713.1 lipoprotein-releasing ABC transporter permease subunit -
  UW163_RS12225 (UW163_12215) lolD 2622520..2623263 (+) 744 WP_042567698.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  UW163_RS12230 (UW163_12220) - 2623283..2624098 (+) 816 WP_014617397.1 TatD family hydrolase -
  UW163_RS12235 (UW163_12225) comA 2624108..2626648 (+) 2541 WP_014617396.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  UW163_RS12240 (UW163_12230) - 2626754..2628235 (+) 1482 WP_003264255.1 circularly permuted type 2 ATP-grasp protein -
  UW163_RS12245 (UW163_12235) - 2628306..2629268 (+) 963 WP_014617395.1 alpha-E domain-containing protein -
  UW163_RS12250 (UW163_12240) - 2629326..2630162 (+) 837 WP_039549867.1 transglutaminase family protein -
  UW163_RS12255 (UW163_12245) - 2630247..2631161 (+) 915 WP_014617393.1 proteasome-type protease -

Sequence

Protein


Download         Length: 846 a.a.        Molecular weight: 90342.86 Da        Isoelectric Point: 10.1608

>NTDB_id=158375 UW163_RS12235 WP_014617396.1 2624108..2626648(+) (comA) [Ralstonia solanacearum strain UW163]
MRALLIGFVAGCMALQTRPVLVPVWQPVLLALACGLIALALRRAGQSPMLISGIAVLVAACVGFGWSDWRAQQRLSVVLA
PEWEGKAIQATGVVAELPQVTEDATRFLFHIESSDAGDAVPPRVRLSWYGKRNWNERRRERGAIADRRAGIPDLQPGQRW
QLTLRLKRPHSLMNPGGFDGEYAMLADDIRAAGTVQTGKRARNALIGETDAGFGLQVERWRAAVRRHILAALPDARYGPV
MVALVVGDQSGIAQADWERFRRTGISHLVSISGLHITMIAGLFAALWMALWRRSFGLARWLRTPLPLRMPAQRAAAIAAM
AAAFAYCLLAGMGVPAQRTLLMLATVAVARLTDRSVPASLSLCWAAAVVALVDPWAVMSAGFWLSFGAVAVIFLAARMAA
ADAGGDARPSAWLRRAWRGLRGGARIQLAVTVGLLPLTLLLFQQVSVVSAAANALAIPVVSLVTTPLALIGAALPEPWAQ
PVLAWAEASFGWLVSWLDGLSAPAWSVWTAPVAPAWAWLLAIGGVPLLLAPGGHRAWAWRAQGVLLLLPMLLARAPAPPP
GAFRLVAFDIGQGAAALVETAGHRLLFDTGPRYGDLADAADRVIVPYLRGHGVQAIDTLVVSHEDSDHAGGTETVMAGVP
VRTMLASLPPGHRLGERARAYGIDTAGCLAGQRWTWDGVAFEILHPVQAPPDRAPPSSNARSCVLRIAGERHAALLAGDI
GSAQEMALIAAEAPERLMADILLVPHHGSKTSSSGAFLDAVSPQVAIFQVGYRNRYGHPHPQVWQRYGARDIERLRTDAA
GAVVIETGGDALEVRTARSMRPRYWSSALEVAALADATEAPADAQP

Nucleotide


Download         Length: 2541 bp        

>NTDB_id=158375 UW163_RS12235 WP_014617396.1 2624108..2626648(+) (comA) [Ralstonia solanacearum strain UW163]
ATGCGCGCCCTGCTGATCGGCTTTGTCGCGGGGTGCATGGCGTTGCAGACGCGGCCGGTGCTGGTGCCGGTCTGGCAGCC
GGTGCTGCTGGCGCTGGCGTGCGGTTTGATTGCGTTGGCGTTGCGGCGCGCGGGGCAGTCGCCGATGCTCATCTCCGGGA
TTGCCGTGCTGGTGGCTGCGTGTGTCGGTTTCGGCTGGAGCGACTGGCGCGCGCAGCAGCGGCTGTCCGTGGTGCTGGCG
CCCGAATGGGAAGGCAAGGCCATCCAGGCGACGGGCGTCGTGGCCGAGCTGCCGCAGGTCACCGAGGACGCCACGCGTTT
CCTGTTCCACATCGAATCCAGCGACGCAGGCGACGCCGTGCCGCCGCGCGTGCGCCTGTCATGGTATGGCAAGCGCAACT
GGAACGAACGGAGGCGGGAGCGTGGGGCGATCGCCGATCGCCGTGCCGGCATCCCCGACCTGCAGCCCGGCCAGCGCTGG
CAACTGACGCTGCGGCTCAAGCGGCCGCACAGCCTGATGAATCCCGGCGGCTTCGACGGCGAATACGCGATGCTCGCCGA
CGACATCCGCGCCGCGGGCACCGTGCAGACCGGCAAACGCGCGCGCAATGCGCTGATCGGCGAAACCGATGCCGGCTTCG
GTCTCCAGGTCGAGCGCTGGCGTGCCGCGGTGCGGCGGCATATCCTCGCCGCCTTGCCCGATGCGCGTTATGGGCCGGTG
ATGGTCGCCCTGGTGGTGGGCGATCAGAGCGGCATCGCGCAAGCGGATTGGGAGCGCTTCCGCCGCACCGGCATCAGCCA
TCTCGTCAGCATTTCCGGCCTGCACATCACGATGATCGCCGGGCTGTTCGCCGCGCTCTGGATGGCGCTGTGGCGGCGCT
CGTTCGGCCTGGCCCGCTGGTTGCGCACGCCGTTGCCGCTGCGCATGCCGGCCCAGCGCGCCGCCGCCATCGCGGCGATG
GCGGCGGCGTTCGCCTATTGCCTGCTGGCGGGGATGGGCGTGCCGGCGCAGCGCACGCTGCTGATGCTCGCGACCGTCGC
CGTGGCGCGGCTGACCGATCGCAGCGTGCCGGCCAGCCTGTCGCTGTGCTGGGCTGCGGCCGTGGTGGCGCTGGTGGATC
CTTGGGCGGTCATGTCGGCGGGATTTTGGCTGTCGTTCGGCGCGGTGGCGGTCATCTTCCTGGCCGCGCGGATGGCGGCC
GCCGATGCCGGGGGCGATGCCCGGCCATCCGCCTGGCTCAGGCGCGCCTGGCGCGGCCTGCGCGGCGGCGCCCGCATCCA
GTTGGCCGTGACGGTCGGCCTGCTGCCGTTGACGCTGCTGTTGTTCCAGCAGGTCTCGGTGGTGTCGGCCGCGGCCAACG
CGCTCGCGATTCCGGTGGTCAGCCTGGTCACCACGCCGCTGGCGTTGATCGGCGCGGCGCTGCCTGAGCCGTGGGCGCAG
CCGGTGCTGGCGTGGGCCGAGGCCAGCTTCGGGTGGCTCGTGTCGTGGCTGGATGGACTGTCGGCGCCCGCCTGGTCGGT
GTGGACGGCGCCCGTCGCGCCCGCCTGGGCGTGGCTGTTGGCCATCGGCGGCGTGCCGTTGCTGCTCGCGCCGGGCGGGC
ATCGCGCCTGGGCCTGGCGGGCGCAGGGCGTGCTCCTGCTGCTGCCGATGCTGCTCGCTCGTGCGCCGGCACCGCCGCCG
GGCGCGTTCCGCCTGGTCGCATTCGACATCGGTCAGGGCGCCGCCGCGCTGGTCGAGACGGCCGGCCACCGGCTGCTGTT
CGATACCGGCCCGCGCTATGGCGACCTGGCCGATGCCGCCGATCGTGTGATCGTCCCGTATCTGCGCGGACACGGCGTGC
AGGCCATCGATACGCTGGTGGTCAGCCACGAGGACAGCGACCACGCCGGCGGCACCGAAACGGTGATGGCCGGGGTGCCG
GTGCGCACCATGCTGGCGTCCTTGCCGCCCGGCCACCGGCTCGGCGAGCGGGCCCGCGCCTACGGCATCGATACCGCGGG
CTGCCTGGCGGGGCAGCGCTGGACCTGGGATGGCGTTGCCTTCGAAATCCTGCATCCGGTGCAGGCGCCCCCCGATAGGG
CGCCGCCGTCCAGCAACGCCCGCAGCTGCGTGCTGCGCATTGCCGGCGAGCGCCATGCCGCCTTGCTGGCCGGCGACATC
GGCAGCGCCCAGGAAATGGCGCTGATCGCCGCCGAAGCGCCGGAGCGGCTCATGGCAGATATCTTGCTTGTGCCCCATCA
CGGCAGCAAGACGAGCTCCAGCGGTGCGTTTCTGGACGCGGTTTCTCCGCAGGTGGCGATTTTCCAGGTCGGCTACCGCA
ACCGGTATGGTCATCCGCATCCGCAGGTCTGGCAGCGCTACGGCGCGCGCGACATCGAGCGGTTGCGTACCGACGCAGCC
GGGGCCGTCGTCATCGAGACGGGCGGCGATGCACTGGAGGTGCGGACCGCGCGGTCGATGCGGCCGCGCTACTGGTCCTC
GGCGCTCGAGGTGGCAGCCCTGGCAGACGCCACGGAGGCGCCCGCCGACGCGCAGCCGTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(23-197)

Beta-lactamase superfamily domain (Lactamase_B_2)

(583-743)

Competence protein (Competence)

(244-529)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F6G2D6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

85.377

100

0.856

Multiple sequence alignment