Detailed information NTG0158208

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: APQ97_RS03750
• Genome accession: NZ_CP012911
• Coordinates: 761709..763946 (+)
• Length: 745 a.a.
• NCBI ID: WP_002935350.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NSUI060
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 756709..768946

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APQ97_RS03725 (APQ97_03715)	-	756779..757708 (-)	930	WP_002937175.1	ABC transporter substrate-binding protein	-
APQ97_RS03730 (APQ97_03720)	-	757721..758506 (-)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
APQ97_RS03735 (APQ97_03725)	-	758658..760103 (-)	1446	WP_024390938.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
APQ97_RS03740 (APQ97_03730)	-	760250..760996 (+)	747	WP_014636901.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
APQ97_RS03745 (APQ97_03735)	comEA/celA/cilE	761063..761725 (+)	663	WP_002935348.1	helix-hairpin-helix domain-containing protein	Machinery gene
APQ97_RS03750 (APQ97_03740)	comEC/celB	761709..763946 (+)	2238	WP_002935350.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
APQ97_RS12435 (APQ97_03745)	-	763963..764088 (+)	126	Protein_708	IS982 family transposase	-
APQ97_RS03760 (APQ97_03750)	-	764270..764926 (+)	657	WP_002935353.1	CBS domain-containing protein	-
APQ97_RS03765 (APQ97_03755)	-	765020..765847 (+)	828	WP_002935354.1	hypothetical protein	-
APQ97_RS03770 (APQ97_03760)	-	765853..767124 (+)	1272	WP_002935355.1	toxic anion resistance protein	-
APQ97_RS03775 (APQ97_03765)	-	767161..768027 (-)	867	WP_002935357.1	YitT family protein	-
APQ97_RS03780 (APQ97_03770)	tmk	768202..768840 (+)	639	WP_002935358.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84195.14 Da
• Isoelectric Point: 7.3813

>NTDB_id=158208 APQ97_RS03750 WP_002935350.1 761709..763946(+) (comEC/celB) [Streptococcus suis strain NSUI060]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGCQKVQWERADQLA
PEQVTTMQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFVIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVEVGERLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=158208 APQ97_RS03750 WP_002935350.1 761709..763946(+) (comEC/celB) [Streptococcus suis strain NSUI060]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGGCAGTTTTCATCA
AAACGCTGCCGCTTTTAGCCCTATGTGGTCTGTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTGACGACTATGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGATAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGCCTGCCAGCAGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTGTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCGGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATTAATGTCCCTGTTCATGTTGTTGAGGTGGGCGAACGCTTACCAATTTTTGACT
CTTACCTGGAAGTCCTTTATCCAGATGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.836	99.732	0.537
comEC/celB	Streptococcus mitis NCTC 12261	52.632	99.463	0.523
comEC/celB	Streptococcus pneumoniae TIGR4	51.752	99.597	0.515
comEC/celB	Streptococcus pneumoniae Rx1	51.482	99.597	0.513
comEC/celB	Streptococcus pneumoniae D39	51.482	99.597	0.513
comEC/celB	Streptococcus pneumoniae R6	51.482	99.597	0.513
comEC	Lactococcus lactis subsp. cremoris KW2	48.594	100	0.487