Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   APQ97_RS01930 Genome accession   NZ_CP012911
Coordinates   363361..364083 (+) Length   240 a.a.
NCBI ID   WP_002938171.1    Uniprot ID   A0A116M1G6
Organism   Streptococcus suis strain NSUI060     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 358361..369083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ97_RS01905 (APQ97_01895) - 358645..359547 (+) 903 WP_002937414.1 SPFH domain-containing protein -
  APQ97_RS01910 (APQ97_01900) - 359633..359842 (+) 210 WP_009910800.1 hypothetical protein -
  APQ97_RS01915 (APQ97_01905) - 359969..360712 (-) 744 WP_024389055.1 amino acid ABC transporter ATP-binding protein -
  APQ97_RS01920 (APQ97_01910) - 360705..362270 (-) 1566 WP_024394234.1 ABC transporter substrate-binding protein/permease -
  APQ97_RS01925 (APQ97_01915) - 362397..363233 (+) 837 WP_002938173.1 undecaprenyl-diphosphate phosphatase -
  APQ97_RS01930 (APQ97_01920) mecA 363361..364083 (+) 723 WP_002938171.1 adaptor protein MecA Regulator
  APQ97_RS01935 (APQ97_01925) - 364080..365252 (+) 1173 WP_002938168.1 MraY family glycosyltransferase -
  APQ97_RS01945 (APQ97_01935) sufC 365732..366505 (+) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  APQ97_RS01950 (APQ97_01940) sufD 366522..367784 (+) 1263 WP_002938159.1 Fe-S cluster assembly protein SufD -
  APQ97_RS01955 (APQ97_01945) - 367786..369012 (+) 1227 WP_002938158.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27973.51 Da        Isoelectric Point: 4.0497

>NTDB_id=158198 APQ97_RS01930 WP_002938171.1 363361..364083(+) (mecA) [Streptococcus suis strain NSUI060]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=158198 APQ97_RS01930 WP_002938171.1 363361..364083(+) (mecA) [Streptococcus suis strain NSUI060]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116M1G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment