Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SanJ4211_RS02035 Genome accession   NZ_CP012805
Coordinates   385840..386592 (+) Length   250 a.a.
NCBI ID   WP_021001304.1    Uniprot ID   A0AAP6BPK5
Organism   Streptococcus anginosus strain J4211     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 380840..391592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS02020 (SanJ4211_0373) - 382224..383066 (+) 843 WP_021001301.1 undecaprenyl-diphosphate phosphatase -
  SanJ4211_RS02025 (SanJ4211_0374) cas1 383321..384325 (+) 1005 WP_021001302.1 CRISPR-associated endonuclease Cas1 -
  SanJ4211_RS02030 (SanJ4211_0375) cas2 384328..384657 (+) 330 WP_021001303.1 CRISPR-associated endonuclease Cas2 -
  SanJ4211_RS02035 (SanJ4211_0376) mecA 385840..386592 (+) 753 WP_021001304.1 adaptor protein MecA Regulator
  SanJ4211_RS02040 (SanJ4211_0377) - 386583..387749 (+) 1167 WP_041783991.1 glycosyltransferase family 4 protein -
  SanJ4211_RS02045 (SanJ4211_0378) sufC 387842..388612 (+) 771 WP_041783992.1 Fe-S cluster assembly ATPase SufC -
  SanJ4211_RS02050 (SanJ4211_0379) sufD 388652..389914 (+) 1263 WP_021001307.1 Fe-S cluster assembly protein SufD -
  SanJ4211_RS02055 (SanJ4211_0380) - 389930..391162 (+) 1233 WP_021001308.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28968.80 Da        Isoelectric Point: 4.1287

>NTDB_id=157684 SanJ4211_RS02035 WP_021001304.1 385840..386592(+) (mecA) [Streptococcus anginosus strain J4211]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMESEENSDELTQKYIYYIL
KFSSLKEAIVFSKTVDYAVNTSELYKMDDHYYLTILVDIEGRPKRYPAWLLALMREHAEDTDVTRAVLQEHGYLLLVNEA
VASLQKVKCL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=157684 SanJ4211_RS02035 WP_021001304.1 385840..386592(+) (mecA) [Streptococcus anginosus strain J4211]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAGGATTTAGAGGAACGTGGGATGGAAAT
GGCAGATTTTCTAGTCCCACAAGAAAAAACAGAAGAGTTTTTCTATGCGATTTTAGATGAGTTGGAAATGCCAGAGAGCT
TTTTAGATAGCGGCATGCTCAGTTTTCGTGTGACACCAAAGCCCGACCGATTGGATGTCTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTCGATGATTTGGCAGATTTGCCAGATGTAGAAGAGCTGTCTCAAATGTCTCCTGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAGTCAGAGGAAAATAGTGACGAACTAACGCAGAAATATATTTATTACATTTTG
AAATTTTCTAGCCTGAAAGAAGCAATTGTTTTTTCTAAGACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAAAAT
GGACGACCACTATTATTTGACAATCTTGGTTGATATTGAAGGGCGTCCAAAGCGTTATCCAGCTTGGCTCCTGGCTTTGA
TGCGTGAGCATGCAGAGGATACGGATGTGACAAGAGCTGTTTTGCAAGAACACGGTTACTTATTGCTTGTCAACGAGGCG
GTTGCCAGTCTTCAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.397

98.8

0.656
  mecA Streptococcus pneumoniae D39

66.397

98.8

0.656
  mecA Streptococcus pneumoniae R6

66.397

98.8

0.656
  mecA Streptococcus pneumoniae TIGR4

65.992

98.8

0.652
  mecA Streptococcus mutans UA159

50.602

99.6

0.504
  mecA Streptococcus thermophilus LMD-9

45.882

100

0.468
  mecA Streptococcus thermophilus LMG 18311

45.49

100

0.464

Multiple sequence alignment