Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AN924_RS05400 Genome accession   NZ_CP012731
Coordinates   1061455..1062651 (-) Length   398 a.a.
NCBI ID   WP_009911075.1    Uniprot ID   G7SHV4
Organism   Streptococcus suis strain 90-1330     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1056455..1067651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AN924_RS11455 - 1056638..1057066 (-) 429 WP_308690909.1 hypothetical protein -
  AN924_RS11460 - 1057014..1057520 (-) 507 WP_226960614.1 diacylglycerol/lipid kinase family protein -
  AN924_RS05385 (AN924_11290) dnaN 1057764..1058900 (-) 1137 WP_004194538.1 DNA polymerase III subunit beta -
  AN924_RS05390 (AN924_11300) dnaA 1059054..1060427 (-) 1374 WP_004194536.1 chromosomal replication initiator protein DnaA -
  AN924_RS05395 (AN924_11310) spo0J 1060630..1061394 (-) 765 WP_004194534.1 ParB/RepB/Spo0J family partition protein Regulator
  AN924_RS05400 (AN924_11320) htrA 1061455..1062651 (-) 1197 WP_009911075.1 S1C family serine protease Regulator
  AN924_RS05405 (AN924_11330) rlmH 1062825..1063304 (+) 480 WP_004194528.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AN924_RS05410 - 1063329..1064012 (+) 684 WP_004194526.1 YoaK family protein -
  AN924_RS05430 (AN924_11370) - 1064413..1066992 (-) 2580 WP_004194524.1 YfhO family protein -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41818.83 Da        Isoelectric Point: 4.6655

>NTDB_id=157363 AN924_RS05400 WP_009911075.1 1061455..1062651(-) (htrA) [Streptococcus suis strain 90-1330]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPRVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=157363 AN924_RS05400 WP_009911075.1 1061455..1062651(-) (htrA) [Streptococcus suis strain 90-1330]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACGGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCTACTACAAAGGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCTGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(293-389)

Trypsin-like peptidase domain (Trypsin_2)

(103-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SHV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.446

99.749

0.593
  htrA Streptococcus gordonii str. Challis substr. CH1

59.494

99.246

0.59
  htrA Streptococcus pneumoniae D39

57.252

98.744

0.565
  htrA Streptococcus pneumoniae TIGR4

57.252

98.744

0.565
  htrA Streptococcus mitis NCTC 12261

57.252

98.744

0.565
  htrA Streptococcus pneumoniae R6

57.252

98.744

0.565
  htrA Streptococcus pneumoniae Rx1

57.252

98.744

0.565

Multiple sequence alignment