Detailed information NTG0156782

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SanJ4206_RS04350
• Genome accession: NZ_CP012719
• Coordinates: 890104..892332 (+)
• Length: 742 a.a.
• NCBI ID: WP_003029858.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain J4206
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 885104..897332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4206_RS04325	rpmG	885957..886106 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
SanJ4206_RS04330 (SanJ4206_0819)	secG	886146..886379 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
SanJ4206_RS04335 (SanJ4206_0820)	rnr	886471..888804 (+)	2334	WP_003029862.1	ribonuclease R	-
SanJ4206_RS04340 (SanJ4206_0821)	smpB	888767..889234 (+)	468	WP_003029860.1	SsrA-binding protein SmpB	-
SanJ4206_RS04345 (SanJ4206_0822)	comEA/celA/cilE	889416..890120 (+)	705	WP_003029859.1	helix-hairpin-helix domain-containing protein	Machinery gene
SanJ4206_RS04350 (SanJ4206_0823)	comEC/celB	890104..892332 (+)	2229	WP_003029858.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SanJ4206_RS04355 (SanJ4206_0824)	-	892413..893111 (+)	699	WP_003029857.1	DUF805 domain-containing protein	-
SanJ4206_RS09840 (SanJ4206_0825c)	-	893254..893412 (-)	159	WP_003042740.1	hypothetical protein	-
SanJ4206_RS04360 (SanJ4206_0826)	-	893655..894641 (+)	987	WP_022525428.1	Gfo/Idh/MocA family protein	-
SanJ4206_RS04365 (SanJ4206_0827)	-	894663..895316 (+)	654	WP_003029851.1	uracil-DNA glycosylase	-
SanJ4206_RS04370 (SanJ4206_0828)	-	895353..895823 (+)	471	WP_003029850.1	NUDIX hydrolase	-
SanJ4206_RS04375 (SanJ4206_0829)	-	895836..897113 (+)	1278	WP_003029848.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85067.86 Da
• Isoelectric Point: 10.0445

>NTDB_id=156782 SanJ4206_RS04350 WP_003029858.1 890104..892332(+) (comEC/celB) [Streptococcus anginosus strain J4206]
MSQWIKRFPIKPIYIAFLLVWLYFAIYQSSWLACLGFIFLVIRLFRFYSPKEYFMTFMILSCFAGFFFVRREMVEQKTKV
APSPVRQVAVLPDTIKVNGDSLSFRGKTNGQTYQVYYKLKSKEEQLAFQNLSSLAILTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHTFEWLSSWRRRALVFIKKHFPNPMSNYMTGLLFGALDTDFDEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLT
LIFLSSPLIKLTQVNFLFEGLENSIRWIASVFGRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLLLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGIDTIDALVLTNPNP
DYAGDVLEVAKKFAIKKIYISRSSLSNADFLEKLRKINTFIHVVKQGDKLPIFDHHLQVLSGASKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKDSSSSKFLQQIEPTVALISVGKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide

• Length: 2229 bp

>NTDB_id=156782 SanJ4206_RS04350 WP_003029858.1 890104..892332(+) (comEC/celB) [Streptococcus anginosus strain J4206]
ATGTCACAGTGGATTAAAAGATTTCCGATTAAGCCAATTTACATAGCTTTTTTGCTTGTCTGGTTATATTTTGCAATCTA
CCAAAGTAGTTGGTTAGCTTGTCTTGGTTTTATCTTTCTAGTGATTCGTCTTTTTCGCTTTTATTCACCGAAAGAATATT
TCATGACCTTCATGATCCTCTCTTGTTTTGCTGGTTTTTTCTTTGTTCGTAGGGAAATGGTAGAGCAGAAGACGAAAGTA
GCACCCTCTCCCGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCACTTTCTTTCCGTGGTAA
AACAAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGCTATATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGATAGAATCAGCTTGCACACTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAGAGCACTGGTATTTATCAAGAAGCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACAGACTTCGATGAAATGAACAATCTTTACTCTAGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGTTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGCTGGGTCTTACACAGGA
AATGGTCCATAAATGTCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTACTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCTTCCTTTCTTTTAACGGCAGGAGGAGTTCTCTCTTGCGCCTATGCTTTTGTTATTAGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAAGATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTGATTTTCGATACAATGATGCTGCCAGGCTTGACG
TTGATTTTTCTTTCTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GATAGCAAGTGTCTTTGGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGCTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCTTTGCAAAATGAGATCACAATGGTTGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGTGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCGACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGCATAGATACGATTGATGCTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTTCTAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCGGGTGCTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAGGACTCATCAAGTTCAAAATTTTTGCAACAAATAGAACCAACGGTTGCGCTCATTT
CTGTCGGGAAAAATAATCAATCTAAGCAACCAAGCCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAAGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-695)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.556	100	0.559
comEC/celB	Streptococcus mitis NCTC 12261	54.96	100	0.553
comEC/celB	Streptococcus pneumoniae TIGR4	54.618	100	0.55
comEC/celB	Streptococcus pneumoniae Rx1	53.681	100	0.54
comEC/celB	Streptococcus pneumoniae D39	53.681	100	0.54
comEC/celB	Streptococcus pneumoniae R6	53.681	100	0.54
comEC	Lactococcus lactis subsp. cremoris KW2	47.39	100	0.477