Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   RN86_RS10405 Genome accession   NZ_CP012648
Coordinates   2140721..2141560 (-) Length   279 a.a.
NCBI ID   WP_053794810.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2135721..2146560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS11710 - 2136447..2136554 (-) 108 Protein_2024 DNA-entry nuclease -
  RN86_RS10385 (RN86_10390) - 2136847..2137893 (+) 1047 WP_053794806.1 iron ABC transporter permease -
  RN86_RS10390 (RN86_10395) - 2137895..2138650 (+) 756 WP_053794807.1 ABC transporter ATP-binding protein -
  RN86_RS10395 (RN86_10400) - 2138795..2139823 (+) 1029 WP_053794808.1 ABC transporter substrate-binding protein -
  RN86_RS10400 (RN86_10405) - 2139804..2140505 (+) 702 WP_053794809.1 alpha/beta hydrolase-fold protein -
  RN86_RS10405 (RN86_10410) endA 2140721..2141560 (-) 840 WP_053794810.1 DNA/RNA non-specific endonuclease Machinery gene
  RN86_RS10410 (RN86_10415) - 2141605..2141793 (-) 189 WP_045502090.1 DNA-directed RNA polymerase subunit beta -
  RN86_RS10415 (RN86_10420) murA 2141786..2143066 (-) 1281 WP_045634645.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  RN86_RS10420 (RN86_10425) - 2143106..2143339 (-) 234 WP_045502080.1 DUF1146 family protein -
  RN86_RS10425 (RN86_10430) tpiA 2143469..2144227 (-) 759 WP_012000225.1 triose-phosphate isomerase -
  RN86_RS10430 (RN86_10435) tuf 2144501..2145697 (-) 1197 WP_020992675.1 elongation factor Tu -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30811.47 Da        Isoelectric Point: 10.0100

>NTDB_id=156110 RN86_RS10405 WP_053794810.1 2140721..2141560(-) (endA) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MKKKQEEKLFQSIVGLILALVLIAGANYFSNHQNQDNIKSNPQVQRTGRRDISTPEQALSQSVLTDSVRKQLKGSIEWNQ
AGAFIINGNKTDLNADIASQPYAQNQTKSVQGQLVPIIGNALLSKQTRQYKNREETGNGTTSWVPAGWHQVRNLSGDFNH
AVDRGHLLAYSLVGGLKNFDASTSNPENIAVQTAWANQANSPSSTGQNFYESLIRKALDKKKRVRYRVTLIYANPDDLIA
AGSHLEAKSSDGSLEFNVFVPNIQTGIRINYRTGEVTVE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=156110 RN86_RS10405 WP_053794810.1 2140721..2141560(-) (endA) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGAAGAAGAAACAAGAAGAGAAACTCTTTCAAAGCATAGTAGGACTGATTCTGGCACTTGTTCTGATAGCTGGTGCTAA
TTATTTCTCAAACCATCAGAATCAGGATAACATAAAGTCTAATCCACAGGTTCAAAGAACAGGAAGAAGGGATATCTCAA
CTCCCGAGCAAGCACTATCTCAGAGTGTATTGACTGATTCTGTTCGTAAGCAATTAAAAGGTAGCATAGAATGGAATCAG
GCAGGTGCTTTTATTATTAATGGCAACAAGACAGACTTGAATGCTGATATTGCCAGTCAGCCTTATGCACAAAATCAAAC
GAAGTCAGTTCAGGGACAGTTAGTACCAATAATTGGGAATGCTCTGCTTTCTAAACAGACTAGACAATACAAAAATCGAG
AAGAAACCGGAAACGGAACGACAAGTTGGGTTCCCGCCGGCTGGCATCAAGTGAGAAATCTTAGTGGAGATTTTAATCAT
GCTGTTGACCGAGGGCATTTATTAGCTTATTCTTTAGTCGGAGGCTTAAAGAACTTCGATGCTTCTACAAGTAACCCAGA
GAATATCGCTGTTCAAACAGCTTGGGCAAATCAGGCAAACAGTCCTTCGTCTACTGGACAAAATTTTTATGAAAGCTTGA
TTCGGAAGGCTTTGGATAAAAAGAAGCGAGTTCGTTATCGAGTAACCTTGATTTATGCTAATCCTGATGACTTAATAGCA
GCGGGCTCTCATTTAGAAGCAAAGTCTAGCGATGGAAGTCTTGAGTTTAATGTCTTCGTTCCAAATATTCAAACCGGGAT
TCGTATCAACTATAGAACTGGAGAAGTAACTGTAGAGTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(82-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.75

80.287

0.552
  endA Streptococcus pneumoniae D39

68.75

80.287

0.552
  endA Streptococcus pneumoniae R6

68.75

80.287

0.552
  endA Streptococcus pneumoniae TIGR4

68.75

80.287

0.552

Multiple sequence alignment