Detailed information NTG0156112

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: RN86_RS10775
• Genome accession: NZ_CP012648
• Coordinates: 2214533..2216794 (+)
• Length: 753 a.a.
• NCBI ID: WP_046165885.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain KCOM 1506 (= ChDC B679)
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2209533..2221794

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN86_RS10745 (RN86_10750)	-	2209657..2209869 (-)	213	WP_008809086.1	exodeoxyribonuclease VII small subunit	-
RN86_RS10750 (RN86_10755)	xseA	2209847..2211187 (-)	1341	WP_053794835.1	exodeoxyribonuclease VII large subunit	-
RN86_RS10755 (RN86_10760)	-	2211343..2212185 (-)	843	WP_053794836.1	NAD(P)H-hydrate dehydratase	-
RN86_RS10760 (RN86_10765)	-	2212293..2213066 (-)	774	WP_053794837.1	HAD hydrolase family protein	-
RN86_RS10765 (RN86_10770)	-	2213063..2213917 (-)	855	WP_046165884.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
RN86_RS10770 (RN86_10775)	-	2214050..2214280 (-)	231	WP_008809091.1	DUF1797 family protein	-
RN86_RS10775 (RN86_10780)	clpE	2214533..2216794 (+)	2262	WP_046165885.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
RN86_RS10780 (RN86_10785)	-	2216845..2217450 (-)	606	WP_046165886.1	GyrI-like domain-containing protein	-
RN86_RS10785 (RN86_10790)	-	2217510..2218400 (-)	891	WP_053794838.1	YafY family protein	-
RN86_RS10790 (RN86_10795)	-	2218559..2219011 (+)	453	WP_046165888.1	NUDIX hydrolase	-
RN86_RS10795 (RN86_10800)	-	2219110..2219409 (+)	300	WP_045773849.1	DUF1827 family protein	-
RN86_RS10800 (RN86_10805)	-	2219446..2219883 (-)	438	WP_053794839.1	GNAT family N-acetyltransferase	-
RN86_RS10805 (RN86_10810)	-	2219906..2220361 (+)	456	WP_046165890.1	MarR family transcriptional regulator	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83944.04 Da
• Isoelectric Point: 5.0247

>NTDB_id=156112 RN86_RS10775 WP_046165885.1 2214533..2216794(+) (clpE) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MLCQNCKINESTIHLYTNVNGKKQQVDLCQNCYQIMKTDPNNSLLGGLTNMNNHNMDPFDDFFNHLGNFQGPKDSTPPTQ
SGGSYGGGNYGPGSNNQRPQSASNKPKGLLEEFGINVTEIARRGDIDPVIGRDDEIRRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDNDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRNRNDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVRYTDEAIEA
AAILSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDRRLIEAENLKTQATRDEDYEKAAYFRDQIAKYKEMQNA
KMDEQDTPIISEKEIEAIVEQKTNIPVGDLKEKEQSQLIHLASDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVDLMLEDVNNRLASNEIHLDVTAKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPTDK
DLKAIMTSNGKIIIKGKKKAELDQTTDISTSSD

Nucleotide

• Length: 2262 bp

>NTDB_id=156112 RN86_RS10775 WP_046165885.1 2214533..2216794(+) (clpE) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGCTTTGTCAAAACTGTAAAATCAATGAATCTACCATTCATTTATACACTAATGTAAATGGTAAAAAACAACAAGTTGA
CCTCTGTCAAAATTGCTATCAGATTATGAAAACTGATCCAAATAACTCACTTTTGGGTGGACTGACGAACATGAATAATC
ATAATATGGATCCTTTTGATGATTTCTTTAATCATCTGGGAAATTTCCAAGGGCCGAAGGATTCTACCCCTCCAACTCAA
TCAGGTGGTAGTTATGGAGGGGGCAACTATGGTCCTGGTTCTAACAACCAGCGTCCTCAGTCAGCCTCCAATAAACCAAA
AGGTCTTTTGGAAGAGTTTGGCATTAACGTTACAGAAATTGCTCGACGTGGTGATATTGATCCAGTGATTGGACGAGATG
ATGAAATTCGTCGTGTTATAGAAATTCTCAATCGCCGAACTAAGAATAACCCAGTCCTTATTGGTGAACCTGGTGTCGGG
AAGACTGCTGTTGTAGAGGGCTTGGCACAGAAAATAGTCGACAATGATGTCCCTCAAAAACTTCAAGGAAAAGAGGTCAT
TCGACTTGATGTTGTCAGCCTTGTTCAAGGAACTGGTATTCGTGGGCAATTTGAAGAACGAATGCAAAAACTCATGGATG
AGATTCGCAATCGCAATGACATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGAGCTGGCTCTGCGGGCGACGGT
AATATGGATGCTGGAAATATTCTCAAACCTGCTCTTGCTCGAGGTGAACTTCAACTGGTCGGAGCTACTACTCTCAATGA
ATACCGAATCATTGAAAAAGATGCAGCATTAGAAAGACGGATGCAACCAGTCAAAGTAGATGAACCAACCGTAGAAGAAA
CGATCACAATTCTAAAGGGGATTCAAAAGAAATACGAAGATTACCACCATGTTCGCTACACAGATGAAGCTATTGAAGCT
GCTGCCATCCTATCCAATCGTTATATTCAGGACCGTTTCCTTCCCGATAAAGCTATTGATCTTTTGGATGAATCAGGATC
TAAGATGAACCTAACCCTCAATTTTGTTGATCCAAAAGAAATTGACAGACGCTTGATAGAGGCTGAAAATCTGAAAACAC
AGGCCACTCGCGATGAAGATTACGAAAAAGCAGCCTACTTCCGCGACCAAATTGCCAAATATAAGGAAATGCAAAATGCT
AAAATGGATGAACAAGATACTCCTATCATCAGTGAGAAGGAGATCGAAGCTATTGTCGAGCAAAAAACAAATATTCCTGT
TGGTGATTTGAAGGAAAAAGAGCAGTCTCAGCTTATTCATTTAGCTAGTGATTTGAAGTCTCATGTCATTGGTCAGGATG
ATGCTGTTGATAAGATTGCAAAAGCCATCCGTCGTAATCGTGTGGGATTAGGCAGTCCAAACCGGCCAATCGGAAGTTTC
CTTTTTGTTGGACCGACAGGCGTTGGAAAAACTGAACTTTCCAAACAATTGGCCATCGAACTTTTTGGCTCTGCCGATAG
CATGATTCGTTTTGATATGAGTGAATACATGGAAAAACATAGCGTTGCCAAACTTGTAGGAGCACCTCCAGGCTACGTTG
GCTATGAAGAAGCAGGCCAGTTGACTGAACGTGTTCGTCGTAATCCATACTCACTCATTCTCTTAGACGAAGTAGAAAAA
GCCCATCCAGATGTCATGCATATGTTCTTACAAGTCTTAGATGACGGACGTTTGACTGATGGACAAGGTCGAACAGTCAG
CTTCAAAGATACCATTATCATTATGACTTCCAATGCAGGAACCGGTAAAGTGGAAGCAAGCGTTGGTTTTGGAGCCGCCC
GAGAAGGTCGAACAAATTCTGTCTTAGGTGAGTTAGGTAACTTCTTTAGTCCAGAATTCATGAACCGATTTGATGGTATT
ATTGAATTCAAGGCATTAAGCAAGGACAATCTCTTACAAATTGTGGATCTAATGCTGGAAGATGTTAATAATCGACTTGC
TAGCAACGAAATTCATCTAGATGTAACAGCTAAAGTCAAAGAAAAATTGGTTGATCTGGGCTACGATCCTAAGATGGGGG
CACGACCACTCCGCAGAACCATTCAGGACCATATCGAAGATGCTATTACGGACTACTACCTAGAACATCCGACAGATAAG
GATTTAAAAGCAATTATGACTAGCAATGGCAAGATTATAATTAAGGGGAAAAAGAAAGCTGAGCTTGATCAAACAACCGA
CATCAGCACAAGCTCAGATTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (152-271)

• AAA lid domain (AAA_lid_9) (290-387)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (646-718)

• AAA domain (Cdc48 subfamily) (AAA_2) (475-638)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.729	99.07	0.859
clpE	Streptococcus pneumoniae D39	86.729	99.07	0.859
clpE	Streptococcus pneumoniae R6	86.729	99.07	0.859
clpE	Streptococcus pneumoniae TIGR4	86.595	99.07	0.858
clpE	Streptococcus mutans UA159	85.121	99.07	0.843
clpC	Lactococcus lactis subsp. cremoris KW2	77.321	100	0.774
clpC	Bacillus subtilis subsp. subtilis str. 168	50.74	89.774	0.456
clpC	Streptococcus pneumoniae D39	47.84	83.001	0.397
clpC	Streptococcus pneumoniae Rx1	47.84	83.001	0.397
clpC	Streptococcus pneumoniae TIGR4	47.68	83.001	0.396
clpC	Streptococcus mutans UA159	46.406	84.993	0.394
clpC	Streptococcus thermophilus LMD-9	44.985	87.384	0.393
clpC	Streptococcus thermophilus LMG 18311	45.038	86.985	0.392
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.603	84.064	0.392