Detailed information NTG0156097

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RN86_RS06015
• Genome accession: NZ_CP012648
• Coordinates: 1230616..1232856 (+)
• Length: 746 a.a.
• NCBI ID: WP_046165271.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain KCOM 1506 (= ChDC B679)
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1225616..1237856

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN86_RS05995 (RN86_05990)	-	1226065..1228434 (-)	2370	WP_046165268.1	cation-translocating P-type ATPase	-
RN86_RS06000 (RN86_05995)	-	1228564..1229304 (+)	741	WP_046165938.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
RN86_RS06005 (RN86_06000)	-	1229343..1229870 (+)	528	WP_046165269.1	HXXEE domain-containing protein	-
RN86_RS06010 (RN86_06005)	comEA/celA/cilE	1229967..1230632 (+)	666	WP_046165270.1	helix-hairpin-helix domain-containing protein	Machinery gene
RN86_RS06015 (RN86_06010)	comEC/celB	1230616..1232856 (+)	2241	WP_046165271.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RN86_RS06020 (RN86_06015)	holA	1232947..1233984 (+)	1038	WP_045773123.1	DNA polymerase III subunit delta	-
RN86_RS06025 (RN86_06020)	-	1234057..1234662 (+)	606	WP_045773124.1	superoxide dismutase	-
RN86_RS06030 (RN86_06025)	-	1234774..1235847 (+)	1074	WP_125443582.1	serine hydrolase	-
RN86_RS06035 (RN86_06030)	-	1236053..1236841 (+)	789	WP_046165272.1	YhfC family glutamic-type intramembrane protease	-
RN86_RS06040 (RN86_06035)	-	1236819..1237100 (+)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
RN86_RS06045 (RN86_06040)	-	1237087..1237584 (+)	498	WP_046165273.1	DUF1648 domain-containing protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85434.32 Da
• Isoelectric Point: 9.7431

>NTDB_id=156097 RN86_RS06015 WP_046165271.1 1230616..1232856(+) (comEC/celB) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MSQWIKKLPLAPIYLCFLLVWLYFAIYSGERLAYLGFSLLIARLIWHYPRKKWLPTLAILIAFSIFFYARRELTEQAFQT
QPAPARQVLVLPDTVKVNGDSLSFRGRIDGRLYQLYYKLASPREKKSFQKLADLVTLEIEAEFNLAEGRRNFSGFDYQAY
LKSQGIYRTVKISRIMSSHSGQSINPFDWLSVWRRKALVFIKTTFPSPMSHYMTGLLFGDLDIEFAEMNDLYSSLGIIHL
FALSGMQVGFFMDAFRKILLRIGLRMETVDWLQFPLSFVYAGLTGFSVSVVRSLVQKLLSQFGVRHLDNFAMTIMTLMFL
MPSFLLTTGGVLSCAYAFIITMLDFEDFSSFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDTFMLPLLS
LIFLISPLFAFTQVNIFFQWLEMVIRWVASLSTRPIILGQPNLPLLIILLLVLALLYDFRKQKKIRVCLSLLAILLFFLS
KHPLQNEITVVDIGQGDSIFLRDISGRTIVIDAGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDRLDKLVLTHTDT
DHMGDMLELAKHFSIREIYVSKGSMTQADFVDKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLGQGDGGNDDSIVLYGEF
FQTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHKETLDRFEKIQ
TKILRTDERGAIRFKGWNSWKIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=156097 RN86_RS06015 WP_046165271.1 1230616..1232856(+) (comEC/celB) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGTCACAGTGGATTAAAAAACTTCCCCTTGCTCCAATCTACTTGTGCTTTCTTTTGGTTTGGCTATACTTTGCTATTTA
TAGTGGTGAAAGGCTCGCTTATCTAGGTTTTTCCCTGCTTATAGCTCGCCTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTTTAGCTATTCTAATTGCTTTCTCTATCTTTTTTTATGCTAGACGTGAGTTGACGGAACAAGCTTTTCAGACT
CAACCAGCTCCAGCAAGACAAGTTCTTGTTTTACCAGATACTGTTAAAGTGAATGGAGATTCCCTATCTTTCCGTGGTAG
AATAGACGGAAGACTTTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAATCATTTCAGAAACTAGCAGACT
TGGTCACTTTAGAAATAGAAGCAGAGTTTAATCTAGCAGAAGGTCGGCGAAATTTTTCTGGTTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATATATCGGACAGTTAAGATCAGTAGGATTATGTCCAGTCACTCTGGTCAATCTATCAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGACTACGTTTCCAAGTCCAATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTGGATATTGAATTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAGGTTGGCTTTTTTATGGATGCCTTTCGGAAAATTCTTTTGCGCATAGGCTTAAGGATGGA
AACGGTAGATTGGTTGCAATTCCCGTTGTCCTTTGTTTATGCAGGTTTGACTGGATTTTCTGTGTCAGTAGTGAGGAGTT
TAGTGCAAAAATTATTGTCTCAATTTGGAGTGAGGCACTTGGATAATTTTGCGATGACCATAATGACCTTGATGTTTCTT
ATGCCGAGTTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACTATGTTGGATTTTGAGGA
TTTTAGTAGCTTTCGTAAAGCCGTGCTAGAGAGTTTAAGTATCTCGTTAGGCATTTTACCGATTCTTATCTACTATTTTG
CAGAATTCCAACCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTCTTTGATACATTTATGTTGCCTCTCTTGAGT
CTGATTTTTCTCATTTCGCCTTTGTTTGCCTTCACTCAAGTTAACATCTTCTTCCAATGGCTGGAAATGGTGATTCGCTG
GGTAGCTAGTTTGTCAACAAGGCCGATAATTTTAGGACAGCCAAATCTACCTTTGCTTATTATTCTCCTACTAGTCTTAG
CCCTGCTCTATGACTTTAGAAAACAAAAAAAGATTAGGGTTTGTCTGAGTCTCTTAGCAATCTTACTATTTTTCCTAAGT
AAACATCCCTTACAAAATGAAATCACAGTAGTTGATATTGGGCAGGGAGACAGTATATTTCTGAGAGATATTAGTGGCCG
AACCATTGTAATTGATGCAGGGGGGCGGGTGGAGATTGGTAAAAAAGAGGCTTGGCAAGAACGAGTTAGAAAAAGCAATG
CGGAAACGACCTTAATCCCTTATCTAAAAAGCCGAGGAGTGGATCGATTGGATAAATTGGTCTTGACTCACACCGATACA
GACCATATGGGAGATATGTTGGAGTTAGCTAAGCACTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
AGCTGATTTTGTAGACAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTGGTCGAGGTAGGAGATCGGCTTCCTATTTTTG
ATTCTGCCCTTGAAGTGCTCTATCCACTCGGTCAAGGAGATGGTGGTAATGATGACTCGATTGTCTTGTATGGTGAATTT
TTCCAAACAAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAACCGTTACCAACATCCGCATAAGGAAACTTTAGATAGATTCGAAAAAATCCAG
ACCAAGATTTTACGAACAGATGAGCGGGGTGCTATTCGATTTAAAGGCTGGAATTCTTGGAAGATAGAAACGGTTCGTTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.697	100	0.578
comEC/celB	Streptococcus mitis NCTC 12261	57.239	100	0.572
comEC/celB	Streptococcus pneumoniae TIGR4	56.627	100	0.567
comEC/celB	Streptococcus pneumoniae Rx1	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae D39	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae R6	56.359	100	0.564
comEC	Lactococcus lactis subsp. cremoris KW2	49.059	99.732	0.489