Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   RN86_RS04170 Genome accession   NZ_CP012648
Coordinates   844800..845093 (+) Length   97 a.a.
NCBI ID   WP_046164733.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 839800..850093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS04145 (RN86_04140) - 841751..842119 (+) 369 WP_046164737.1 DUF1033 family protein -
  RN86_RS04150 (RN86_04145) comYA 842221..843159 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  RN86_RS04155 (RN86_04150) comYB 843092..844126 (+) 1035 WP_046164735.1 competence type IV pilus assembly protein ComGB Machinery gene
  RN86_RS04160 (RN86_04155) comYC 844123..844440 (+) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  RN86_RS04165 (RN86_04160) comYD 844400..844828 (+) 429 WP_069097080.1 competence type IV pilus minor pilin ComGD Machinery gene
  RN86_RS04170 (RN86_04165) comGE/cglE 844800..845093 (+) 294 WP_046164733.1 competence type IV pilus minor pilin ComGE Machinery gene
  RN86_RS04175 (RN86_04170) comGF/cglF 845077..845514 (+) 438 WP_053794327.1 competence type IV pilus minor pilin ComGF Machinery gene
  RN86_RS04180 (RN86_04175) comGG 845495..845926 (+) 432 WP_253276489.1 competence type IV pilus minor pilin ComGG -
  RN86_RS04185 (RN86_04180) comYH 845957..846910 (+) 954 WP_053794328.1 class I SAM-dependent methyltransferase Machinery gene
  RN86_RS04190 (RN86_04185) - 846960..848150 (+) 1191 WP_045634156.1 acetate kinase -
  RN86_RS04195 (RN86_04190) - 848197..848862 (+) 666 WP_053794329.1 type II CAAX endopeptidase family protein -
  RN86_RS04200 (RN86_04195) folP 848939..849904 (+) 966 WP_053794330.1 dihydropteroate synthase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10943.95 Da        Isoelectric Point: 10.6470

>NTDB_id=156074 RN86_RS04170 WP_046164733.1 844800..845093(+) (comGE/cglE) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MVNLRKRQIKGTILLEALLALGVFAVIASLLLGQITQSRKEAAAILEKEEVLRVAQMALQTGQDHLSLNGIEIRIQRTKD
QIRVFHQGKELMDVEKR

Nucleotide


Download         Length: 294 bp        

>NTDB_id=156074 RN86_RS04170 WP_046164733.1 844800..845093(+) (comGE/cglE) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGGTAAATTTAAGAAAACGACAAATTAAAGGGACCATCTTACTGGAAGCCTTACTGGCTTTGGGAGTTTTTGCTGTAAT
TGCAAGCTTGTTACTAGGTCAAATCACGCAATCACGCAAAGAAGCAGCTGCCATTTTAGAAAAAGAGGAGGTCCTGCGGG
TGGCCCAGATGGCCCTCCAAACAGGGCAGGACCATCTTTCCTTAAATGGTATTGAAATTCGTATCCAGAGAACGAAGGAT
CAGATTCGAGTGTTCCATCAAGGAAAGGAGTTGATGGATGTTGAAAAAAGGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

52.688

95.876

0.505
  comGE/cglE Streptococcus pneumoniae D39

52.688

95.876

0.505
  comGE/cglE Streptococcus pneumoniae R6

52.688

95.876

0.505
  comGE/cglE Streptococcus pneumoniae TIGR4

52.688

95.876

0.505
  comGE/cglE Streptococcus mitis NCTC 12261

50.538

95.876

0.485
  comGE/cglE Streptococcus mitis SK321

50.538

95.876

0.485
  comYE Streptococcus mutans UA140

40.206

100

0.402
  comYE Streptococcus mutans UA159

40.206

100

0.402

Multiple sequence alignment