Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RN80_RS07890 Genome accession   NZ_CP012646
Coordinates   1606986..1607723 (-) Length   245 a.a.
NCBI ID   WP_060628564.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1601986..1612723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS07875 (RN80_07890) msrB 1603525..1604463 (-) 939 WP_060628561.1 peptide-methionine (R)-S-oxide reductase MsrB -
  RN80_RS07880 (RN80_07895) thrB 1604677..1605546 (-) 870 WP_060628562.1 homoserine kinase -
  RN80_RS07885 (RN80_07900) - 1605548..1606834 (-) 1287 WP_060628563.1 homoserine dehydrogenase -
  RN80_RS07890 (RN80_07905) mecA 1606986..1607723 (-) 738 WP_060628564.1 adaptor protein MecA Regulator
  RN80_RS07895 (RN80_07910) - 1608038..1609072 (-) 1035 WP_060628565.1 hypothetical protein -
  RN80_RS07900 (RN80_07915) - 1609065..1610534 (-) 1470 WP_060628566.1 O-antigen polysaccharide polymerase Wzy family protein -
  RN80_RS07905 (RN80_07920) - 1610550..1611536 (-) 987 WP_060628567.1 glycosyltransferase family 2 protein -
  RN80_RS07910 (RN80_07925) - 1611538..1612641 (-) 1104 WP_080998530.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28463.33 Da        Isoelectric Point: 4.0422

>NTDB_id=156036 RN80_RS07890 WP_060628564.1 1606986..1607723(-) (mecA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPESFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSNLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVLN
LQKIV

Nucleotide


Download         Length: 738 bp        

>NTDB_id=156036 RN80_RS07890 WP_060628564.1 1606986..1607723(-) (mecA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGAGGAATGGAGAT
TGCTGACTTTCTTGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAATTAGAGATGCCTGAGAGCT
TTTTGGATACAGGTATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTAACCAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGATTTATCGAATTTGCCAGATATGGAAGAATTGGCTCAAATGTCGCCAGATGAGTTTAT
TAAAACCTTAGAAAAAAGCATCGCGGATAAAACCAAGGATGATATTGAAGCCATTCAATCTCTAGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAGGAGCAGGCTGAACAAGAAGCTGAAAGCAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTGGCTTTTGCCAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAATGAGCG
CTATTATTTGACTATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTTTTGGCGCGTATGCGCGAGT
TTGCGGACGATAGTGACATCAGTCGCTCTGTTTTGCAAGAGTATGGCCAAGTCTTGATGAATCACGATGCAGTGCTTAAT
CTGCAAAAGATTGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

98.361

99.592

0.98
  mecA Streptococcus pneumoniae D39

98.361

99.592

0.98
  mecA Streptococcus pneumoniae R6

98.361

99.592

0.98
  mecA Streptococcus pneumoniae TIGR4

97.951

99.592

0.976
  mecA Streptococcus thermophilus LMD-9

47.39

100

0.482
  mecA Streptococcus mutans UA159

47.951

99.592

0.478
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.478

Multiple sequence alignment