Detailed information NTG0156029

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RN80_RS07140
• Genome accession: NZ_CP012646
• Coordinates: 1464633..1466873 (-)
• Length: 746 a.a.
• NCBI ID: WP_060628473.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain KCOM 1350 (= ChDC B183)
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1459633..1471873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN80_RS07105 (RN80_07120)	-	1460538..1460918 (-)	381	WP_000157153.1	VOC family protein	-
RN80_RS07110 (RN80_07125)	rplT	1460977..1461336 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
RN80_RS07115 (RN80_07130)	rpmI	1461388..1461588 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
RN80_RS07120 (RN80_07135)	infC	1461621..1462151 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
RN80_RS07125 (RN80_07140)	-	1462459..1463643 (-)	1185	WP_060628469.1	hypothetical protein	-
RN80_RS07130 (RN80_07145)	-	1463647..1464234 (-)	588	WP_060628471.1	ATP-binding cassette domain-containing protein	-
RN80_RS07140 (RN80_07155)	comEC/celB	1464633..1466873 (-)	2241	WP_060628473.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RN80_RS07145 (RN80_07160)	comEA/celA/cilE	1466857..1467495 (-)	639	WP_060628475.1	helix-hairpin-helix domain-containing protein	Machinery gene
RN80_RS07150 (RN80_07165)	-	1467562..1468131 (-)	570	WP_060628477.1	GNAT family N-acetyltransferase	-
RN80_RS07155 (RN80_07170)	-	1468238..1469242 (-)	1005	WP_060628478.1	PhoH family protein	-
RN80_RS07160 (RN80_07175)	-	1469323..1469538 (-)	216	WP_001232084.1	YozE family protein	-
RN80_RS07165 (RN80_07180)	-	1469584..1470141 (-)	558	WP_004234343.1	GrpB family protein	-
RN80_RS07170 (RN80_07185)	cvfB	1470153..1471007 (-)	855	WP_060628479.1	RNA-binding virulence regulatory protein CvfB	-
RN80_RS07175 (RN80_07190)	frr	1471067..1471624 (-)	558	WP_060628480.1	ribosome recycling factor	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84640.10 Da
• Isoelectric Point: 9.3495

>NTDB_id=156029 RN80_RS07140 WP_060628473.1 1464633..1466873(-) (comEC/celB) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MLQWTKNFPIPLIYLSFLLLWLYYAIFSVSYLALLGFVFLLVCLFIQFLWKSAGKVLVICGIFGFWFVFQNWQQSQASQN
LSDSVEIVRILPDTIKVNGNSLSFRGKADGRIFQVYYKLQSEEEKEVFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQILNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKVLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEEEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFALSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNAWLLILLLISLAFVYDLRKNIKRVAGFSLLIVGLFFLTK
YPLENEITMLDVGQGESIFLRDVNGKTILIDVGGKAKSDKKIEKWQEKATTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
ERVGDLLEVTKAFHVGEILVSKGRLKQKEFVAELEATQTKVRSVTAGENLPIFGSQLEVLAPRKIGDGGYDDSLVLYGKL
LDKYFLFTGNLEEKGEKELLKHYPDLKVDVLKAGQHGSKKSSSSAFLEQLKPEFTLISVGKSNRTKLPHQETLTRLEGIN
SKVYRTDQQGAICFKGWNSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=156029 RN80_RS07140 WP_060628473.1 1464633..1466873(-) (comEC/celB) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGTTACAGTGGACTAAGAATTTCCCCATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTACTACGCTATTTT
CTCAGTATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCTTTGGAAATCTGCTG
GAAAAGTTCTAGTAATTTGTGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGTCAGATTCTGTTGAAATTGTACGGATTTTACCTGACACTATTAAGGTTAATGGTAATAGTCTATCCTTTCGGGGCAA
GGCCGATGGCCGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGTCTTTCAAGCTTTAACCGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGATTCTTAATATTAAAAGAATCCAGTCACTTCAAAAGGTTGGCAGTTGGGATATAGG
AGAAAATCTATCCAGTTTACGCCGAAAGGCTGTGGTTTGGATAAAGACACATTTTCCAGACCCTATGCGCAATTACATGA
CAGGGCTCTTGCTAGGACATCTGGACACGGACTTTGAGGAGATGAATGAGCTTTATTCTAGTTTAGGAATTATCCACCTT
TTTGCCTTGTCGGGGATGCAGGTAGGCTTTTTTATGGATGGCTTTAAGAAACTTCTCTTGCGATTAGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCAGGGCTGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TTTTGCAAAAGTTACTGGCTCAACATGGTGTTAAGGTCTTGGATAATTTTGCCTTGACGGTCCTTGTCCTCTTTATCGTC
ATGCCCAACTTTTTCCTGACTGCAGGAGGAGTTTTGTCCTGCGCTTATGCTTTTATCTTGACCATGACCAGCAAAGAAGA
GGAGGGGCTCAAGGCTGTTGCTAGAGAAAGTCTAGTCATTTCTTTGGGAATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCCATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGCCCTTTCCTTTCTCTATCCAGTCATTCAGCTTAATTTTATTTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
CTCACAGGTGGCAAGTAGACCTCTAGTCTTTGGACAACCCAATGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TTGTCTATGATTTGAGGAAAAATATCAAAAGAGTAGCTGGCTTCAGCTTACTTATTGTGGGTCTCTTTTTCCTGACCAAG
TATCCACTGGAAAATGAAATTACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAAATGGGAAGAC
CATTCTCATAGATGTGGGCGGTAAGGCAAAATCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGATAAGATTGACCAGCTAATTTTGACAAATACGGACAAG
GAACGTGTTGGTGATTTGTTGGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTGTCAAAAGGCCGTCTGAAACA
GAAGGAATTTGTGGCAGAACTAGAGGCAACTCAAACCAAGGTGCGCAGTGTGACAGCAGGAGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTAGCTCCAAGGAAAATAGGAGATGGAGGTTATGATGATTCCCTGGTTCTGTATGGAAAACTT
TTGGATAAGTACTTTCTCTTCACAGGAAATTTGGAGGAAAAAGGAGAGAAGGAATTGCTGAAGCACTATCCAGACTTGAA
AGTGGATGTTTTAAAAGCTGGCCAACATGGCTCTAAAAAATCATCAAGTTCAGCATTTCTAGAACAGCTCAAGCCAGAGT
TTACTCTCATTTCAGTTGGAAAGAGCAATCGAACGAAATTGCCACATCAAGAAACCTTGACTCGACTGGAAGGTATCAAT
AGTAAAGTTTACCGAACTGACCAGCAGGGAGCTATATGCTTTAAAGGGTGGAATAGTTGGAAAATCGAAAGCGTTCGATA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	94.37	100	0.944
comEC/celB	Streptococcus mitis NCTC 12261	92.886	99.866	0.928
comEC/celB	Streptococcus pneumoniae TIGR4	91.555	100	0.916
comEC/celB	Streptococcus pneumoniae Rx1	91.019	100	0.91
comEC/celB	Streptococcus pneumoniae D39	91.019	100	0.91
comEC/celB	Streptococcus pneumoniae R6	91.019	100	0.91
comEC	Lactococcus lactis subsp. cremoris KW2	44.489	99.732	0.444