Detailed information NTG0156023

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: RN80_RS05760
• Genome accession: NZ_CP012646
• Coordinates: 1173835..1174683 (+)
• Length: 282 a.a.
• NCBI ID: WP_060628151.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain KCOM 1350 (= ChDC B183)
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1168835..1179683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN80_RS05735 (RN80_05750)	-	1169558..1170265 (+)	708	WP_060628142.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
RN80_RS05740 (RN80_05755)	-	1170270..1171292 (+)	1023	WP_060628145.1	ribitol-5-phosphate dehydrogenase	-
RN80_RS05745 (RN80_05760)	licA	1171309..1172178 (+)	870	WP_060628148.1	choline kinase LicA	-
RN80_RS05750 (RN80_05765)	-	1172168..1173046 (+)	879	WP_000791828.1	DMT family transporter	-
RN80_RS05755 (RN80_05770)	-	1173058..1173747 (+)	690	WP_020902399.1	CTP--phosphocholine cytidylyltransferase	-
RN80_RS05760 (RN80_05775)	dprA/cilB/dalA	1173835..1174683 (+)	849	WP_060628151.1	DNA-processing protein DprA	Machinery gene
RN80_RS05765 (RN80_05780)	topA	1174801..1176888 (+)	2088	WP_060628155.1	type I DNA topoisomerase	-
RN80_RS05775 (RN80_05790)	-	1177145..1177504 (+)	360	WP_045611815.1	YbaN family protein	-
RN80_RS05780 (RN80_05795)	-	1177597..1178229 (+)	633	WP_060628161.1	copper homeostasis protein CutC	-
RN80_RS05785 (RN80_05800)	-	1178272..1178928 (+)	657	WP_060628162.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31076.71 Da
• Isoelectric Point: 5.2107

>NTDB_id=156023 RN80_RS05760 WP_060628151.1 1173835..1174683(+) (dprA/cilB/dalA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MKITNYEIYKLKKSGLTNQQILNVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLEKEFKKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
SIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=156023 RN80_RS05760 WP_060628151.1 1173835..1174683(+) (dprA/cilB/dalA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAATGTCCTAGAATA
CGGTGAAAATGTTGATCAAGAACTGTTGTTAGGTGATATTGCAGATATATCAGGTTGCCGAAATCCAGCTGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGGAGAAGGAGTTTAAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TACCCTTGGGATTTGAGTGAAATATACGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCTTGAAATTTCC
TAAGGTAGCGGTCGTGGGAAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGATTGGAAA
ATGAACTGGTTATCGTCAGTGGATTAGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
AGCATTGCAGTGATTGGAACAGGTCTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTCAGTGAGTATGGACCAGGCGAACAACCTCTAAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGCCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGCTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGGGC
AAAATTGGTCACCAGTGGGCAGGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	98.582	100	0.986
dprA/cilB/dalA	Streptococcus pneumoniae D39	98.582	100	0.986
dprA/cilB/dalA	Streptococcus pneumoniae R6	98.582	100	0.986
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	98.582	100	0.986
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.872	100	0.979
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55