Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   RN80_RS04030 Genome accession   NZ_CP012646
Coordinates   788878..790779 (+) Length   633 a.a.
NCBI ID   WP_060627670.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 783878..795779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS04015 (RN80_04025) fmt 785885..786820 (+) 936 WP_060627669.1 methionyl-tRNA formyltransferase -
  RN80_RS04020 (RN80_04030) rsmB 786813..788126 (+) 1314 WP_060628752.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  RN80_RS04025 (RN80_04035) - 788141..788881 (+) 741 WP_000406255.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RN80_RS04030 (RN80_04040) stkP 788878..790779 (+) 1902 WP_060627670.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RN80_RS04035 (RN80_04045) - 790868..791626 (+) 759 WP_023946522.1 threonine/serine exporter family protein -
  RN80_RS04040 (RN80_04050) - 791628..792077 (+) 450 WP_060627672.1 threonine/serine exporter family protein -
  RN80_RS04045 (RN80_04055) - 792191..793363 (+) 1173 WP_060627674.1 hydroxymethylglutaryl-CoA synthase -
  RN80_RS04050 (RN80_04060) - 793363..794637 (+) 1275 WP_060627676.1 hydroxymethylglutaryl-CoA reductase, degradative -
  RN80_RS04055 (RN80_04065) - 794674..795639 (-) 966 WP_060627678.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69188.53 Da        Isoelectric Point: 9.4944

>NTDB_id=156013 RN80_RS04030 WP_060627670.1 788878..790779(+) (stkP) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYNRRNEPKLVFNDTTKADTKTLPKVPQSTLTSIPKVQTQSPKPQTA
KPSQQASEDNYATKPVKKRKFRVRYMILLASIVLVAASLIWILSRTPATIAIPNVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPDAGTGRKEGTKINLVVSSGKQSFQLSNYIGRKSTDVIAELKQKKVPENLIKIEEEESSESEEGTV
LRQSPSAGTTYDLSKASTITLTIAKKVTSVAMPSYIGSSLEFTKNNLVQIVGIKEANIEVVEVTTAPSGTAEGTVVEQSP
RAGEKVDLNKTRIKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRGDTHSTNQSSSEGSHENSRN

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=156013 RN80_RS04030 WP_060627670.1 788878..790779(+) (stkP) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTATA
CTTGGCCAAGGATTTGATTCTAGACGGGGAAGAAGTGGCAGTAAAGGTCCTGAGGACCAACTACCAAACAGATCCCATTG
CAGTGGCTCGTTTTCAGCGTGAAGCGAGAGCCATGGCAGATCTGGACCATCCTCATATCGTTCGGATTACAGATATTGGT
GAGGAAGACGGTCAACAGTACTTAGCTATGGAGTACGTAGCAGGACTTGACCTCAAACGCTATATCAAGGAACACCATCC
TCTTTCAAATGAAGAAGCGGTCCGAATCATGGGACAAATCCTCTTGGCTATGCGCTTAGCCCATACTAGAGGCATTGTTC
ACCGCGATTTGAAACCTCAAAATATCCTCTTGACACCAGATGGGACTGCCAAAGTCACAGATTTTGGGATTGCGGTAGCC
TTTGCTGAGACGAGTCTGACTCAGACCAACTCTATGCTGGGCTCGGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAAGCGACTGTACAGAGTGATATCTATGCCATGGGGATCATCTTTTATGAGATGTTGACAGGACATATCCCTTACGATG
GGGATAGTGCAGTGACCATCGCCCTCCAGCATTTCCAGAAACCATTGCCATCGGTTATAGCTGAGAATCCATCTGTGCCT
CAGGCTTTAGAGAATGTTGTCATCAAGGCAACTGCCAAGAAATTGACAGATCGTTATCAGTCAGTTGCAGAGATGTATGT
GGACTTGTCTAGTAGTTTGTCTTATAATCGTCGCAATGAGCCTAAATTGGTGTTTAATGATACCACTAAGGCTGACACCA
AGACTCTTCCTAAAGTTCCACAAAGTACCTTGACTTCGATTCCTAAGGTGCAAACACAAAGTCCAAAGCCACAGACTGCG
AAGCCGAGTCAGCAGGCTTCAGAGGACAATTACGCAACCAAGCCTGTTAAGAAACGGAAATTTAGAGTTCGCTATATGAT
TTTGTTGGCCAGCATTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACAATTGCCATTCCAA
ATGTGGCAGGTCAGACAGTGGCGGAAGCCAAGGAAACCCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAATCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGACGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCTTTCCAATTGAGCAATTATATCGGCCGTAAATCGACCGATGTTATCGCAG
AGCTCAAGCAGAAGAAGGTACCTGAAAATCTCATCAAGATAGAGGAAGAAGAATCAAGCGAGAGTGAAGAAGGAACAGTT
CTTAGACAGAGCCCGTCTGCTGGAACAACTTATGATTTGAGTAAGGCCTCAACAATTACTTTAACTATTGCTAAGAAAGT
AACAAGTGTTGCTATGCCAAGTTATATAGGATCTAGTCTTGAATTTACTAAAAATAATCTCGTTCAAATTGTCGGTATTA
AAGAAGCCAACATTGAAGTTGTAGAAGTTACCACAGCTCCTTCCGGAACTGCTGAAGGTACCGTTGTTGAACAGAGTCCA
AGAGCAGGTGAAAAGGTAGATTTGAATAAGACACGCATCAAGATTTCAATTTACAAACCGAAAACACCGCCGTCAACATC
ATCATCAGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACAACACCAAGTCAGGGGAACCAGCAAGGAAATCAACGAG
GAGATACTCATTCTACTAATCAATCAAGTAGTGAGGGAAGCCACGAAAATTCACGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(510-579)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

80.546

92.575

0.746
  stkP Streptococcus pneumoniae D39

80.205

92.575

0.742
  stkP Streptococcus pneumoniae R6

80.205

92.575

0.742
  stkP Streptococcus pneumoniae Rx1

80.034

92.575

0.741
  stkP/pknB Streptococcus salivarius strain HSISS4

54.872

92.417

0.507
  pknB Streptococcus mutans UA159

54.922

91.469

0.502

Multiple sequence alignment