Detailed information NTG0155998

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: LLUC11_RS09660
• Genome accession: NZ_CP015904
• Coordinates: 1985719..1987602 (-)
• Length: 627 a.a.
• NCBI ID: WP_058207874.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain UC11
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 1980719..1992602

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC11_RS09630 (LLUC11_1867)	-	1981124..1981804 (-)	681	WP_012898438.1	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	-
LLUC11_RS09635 (LLUC11_1868)	macP	1981837..1982115 (-)	279	WP_003130796.1	cell wall synthase accessory phosphoprotein MacP	-
LLUC11_RS09640 (LLUC11_1869)	-	1982108..1982692 (-)	585	WP_012898439.1	NUDIX hydrolase	-
LLUC11_RS09645 (LLUC11_1870)	glmU	1982797..1984173 (-)	1377	WP_003130798.1	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	-
LLUC11_RS09650 (LLUC11_1871)	proC	1984401..1985189 (+)	789	WP_012898440.1	pyrroline-5-carboxylate reductase	-
LLUC11_RS09655 (LLUC11_1872)	rpsO	1985268..1985537 (-)	270	WP_010906184.1	30S ribosomal protein S15	-
LLUC11_RS09660 (LLUC11_1873)	pknB	1985719..1987602 (-)	1884	WP_058207874.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
LLUC11_RS09665 (LLUC11_1874)	-	1987602..1988378 (-)	777	WP_003130802.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
LLUC11_RS09670 (LLUC11_1875)	rsmB	1988459..1989733 (-)	1275	WP_014570715.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LLUC11_RS09675 (LLUC11_1876)	-	1989932..1990438 (-)	507	WP_012898444.1	Asp23/Gls24 family envelope stress response protein	-
LLUC11_RS09680 (LLUC11_1877)	-	1990459..1990647 (-)	189	WP_012898445.1	DUF2273 domain-containing protein	-
LLUC11_RS09685 (LLUC11_1878)	amaP	1990658..1991218 (-)	561	WP_081200072.1	alkaline shock response membrane anchor protein AmaP	-
LLUC11_RS09690 (LLUC11_1879)	-	1991246..1991488 (-)	243	WP_003131476.1	GlsB/YeaQ/YmgE family stress response membrane protein	-

Sequence

Protein

• Length: 627 a.a.
• Molecular weight: 67914.98 Da
• Isoelectric Point: 4.6993

>NTDB_id=155998 LLUC11_RS09660 WP_058207874.1 1985719..1987602(-) (pknB) [Lactococcus lactis subsp. lactis strain UC11]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVVNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLDQAKSKIKDAKLKVGTVHKQQSSTI
AEGNVIKTDPTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPTVGA
SVDPTQEIVITYSVYTAPSSSSTTSESTTTPETSSSTTSSTSSSTTSQPSTDNNNSSKESSTTSSSS

Nucleotide

• Length: 1884 bp

>NTDB_id=155998 LLUC11_RS09660 WP_058207874.1 1985719..1987602(-) (pknB) [Lactococcus lactis subsp. lactis strain UC11]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATCAATCTCAATCCAGAGGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGATCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGACCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGTAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CGCTTGACCAAGCAAAAAGCAAAATTAAAGATGCAAAACTAAAAGTGGGAACAGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAATGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATCTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCCGACGGTTATGTATATTCTGTTTATCCGACTGTTGGAGCG
TCCGTTGATCCAACTCAAGAAATTGTAATCACTTATAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACAACGACGCCTGAAACTTCGTCAAGCACAACTTCAAGTACTTCAAGTTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

• PASTA domain (PASTA) (506-573)

• PASTA domain (PASTA) (365-428)

• PASTA domain (PASTA) (434-501)

• Protein kinase domain (Pkinase) (12-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	48.897	86.762	0.424
stkP/pknB	Streptococcus salivarius strain HSISS4	50.962	82.935	0.423
stkP	Streptococcus pneumoniae TIGR4	48.024	80.702	0.388
stkP	Streptococcus pneumoniae D39	47.826	80.702	0.386
stkP	Streptococcus pneumoniae R6	47.826	80.702	0.386
stkP	Streptococcus pneumoniae Rx1	47.628	80.702	0.384