Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   RN80_RS00240 Genome accession   NZ_CP012646
Coordinates   38550..39287 (-) Length   245 a.a.
NCBI ID   WP_060627129.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 33550..44287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS00210 (RN80_00210) - 34259..34579 (-) 321 WP_060627123.1 hypothetical protein -
  RN80_RS00215 (RN80_00215) - 34874..35278 (-) 405 WP_060627124.1 hypothetical protein -
  RN80_RS00220 - 35339..36007 (-) 669 WP_060627125.1 CPBP family intramembrane glutamic endopeptidase -
  RN80_RS10055 (RN80_00225) - 36365..36484 (-) 120 WP_060627126.1 PncF family bacteriocin immunity protein -
  RN80_RS00235 (RN80_00235) - 37187..38536 (-) 1350 WP_060627128.1 sensor histidine kinase -
  RN80_RS00240 (RN80_00240) comE/blpR 38550..39287 (-) 738 WP_060627129.1 response regulator transcription factor Regulator
  RN80_RS00245 (RN80_00245) - 39583..39912 (+) 330 WP_004261043.1 hypothetical protein -
  RN80_RS00250 (RN80_00250) - 39974..41023 (-) 1050 WP_060627130.1 ABC transporter permease -
  RN80_RS00255 (RN80_00255) pptA 41020..41751 (-) 732 WP_000889954.1 ABC transporter ATP-binding protein Regulator
  RN80_RS00260 (RN80_00260) - 41819..42229 (+) 411 WP_001278319.1 HIT family protein -
  RN80_RS00265 (RN80_00265) - 42239..42520 (+) 282 WP_060627131.1 hypothetical protein -
  RN80_RS00270 (RN80_00270) - 42598..43251 (+) 654 WP_060627132.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28844.99 Da        Isoelectric Point: 6.1689

>NTDB_id=155962 RN80_RS00240 WP_060627129.1 38550..39287(-) (comE/blpR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MRIFVLEDDFSQQTRIETTIEKLLKEHQITPSSFEVFGKPDQLLTEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVRLDKKEKLLFFPNGGSCMIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=155962 RN80_RS00240 WP_060627129.1 38550..39287(-) (comE/blpR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCAGATCACTCCCAGTTCTTTTGAGGTATTTGGGAAGCCAGATCAACTGCTGACTGAAGTCCATGAGAAGGGGGCGCATC
AACTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGGCTGGAAGTGGCTAGAAAAATTCGGGATCGGGAT
CCTTATGCCCTTATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTATCAAGTGTCAGCTTTGGA
CTACATTGATAAGGCCTTGTCGGCAGAGGAGTTTGAATCTCGGATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACATCGCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAGCCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTTCGTTTGGATA
AGAAAGAGAAACTCCTTTTCTTTCCTAATGGCGGAAGCTGTATGATAGCGCGTTATAAGGTCAGGGAAGTGTCTGAAGCT
ATCAATAACTTACATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.733

99.184

0.543
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

39.669

98.776

0.392
  comE Streptococcus infantis strain Atu-4

36.179

100

0.363

Multiple sequence alignment