Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   LLUC06_RS10865 Genome accession   NZ_CP015902
Coordinates   2180835..2182718 (-) Length   627 a.a.
NCBI ID   WP_081213707.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain UC06     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2175835..2187718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC06_RS10835 (LLUC06_2114) - 2176241..2176921 (-) 681 WP_012898438.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  LLUC06_RS10840 (LLUC06_2115) macP 2176953..2177231 (-) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  LLUC06_RS10845 (LLUC06_2116) - 2177224..2177808 (-) 585 WP_033899834.1 NUDIX hydrolase -
  LLUC06_RS10850 (LLUC06_2117) glmU 2177913..2179289 (-) 1377 WP_081213705.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  LLUC06_RS10855 (LLUC06_2118) proC 2179517..2180305 (+) 789 WP_081213706.1 pyrroline-5-carboxylate reductase -
  LLUC06_RS10860 (LLUC06_2119) rpsO 2180384..2180653 (-) 270 WP_015427039.1 30S ribosomal protein S15 -
  LLUC06_RS10865 (LLUC06_2120) stkP/pknB 2180835..2182718 (-) 1884 WP_081213707.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  LLUC06_RS10870 (LLUC06_2121) - 2182718..2183494 (-) 777 WP_058203446.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  LLUC06_RS10875 (LLUC06_2122) rsmB 2183575..2184849 (-) 1275 WP_058203445.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LLUC06_RS10880 (LLUC06_2123) - 2185048..2185554 (-) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  LLUC06_RS10885 (LLUC06_2124) - 2185575..2185763 (-) 189 WP_012898445.1 DUF2273 domain-containing protein -
  LLUC06_RS10890 (LLUC06_2125) amaP 2185774..2186334 (-) 561 WP_010906186.1 alkaline shock response membrane anchor protein AmaP -
  LLUC06_RS10895 (LLUC06_2126) - 2186362..2186604 (-) 243 WP_003131476.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 67927.98 Da        Isoelectric Point: 4.6993

>NTDB_id=155806 LLUC06_RS10865 WP_081213707.1 2180835..2182718(-) (stkP/pknB) [Lactococcus lactis subsp. lactis strain UC06]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVVNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLDQAKSKIKDAKLKVGTVHKQQSSTI
AEGNVIKTDQTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPTVGA
SVDPTQEIVVTYSVYTAPSSSSTTSESTPTPETSSSTTSSTSSSTTSQPSTDNNNSSKESSTTSSSS

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=155806 LLUC06_RS10865 WP_081213707.1 2180835..2182718(-) (stkP/pknB) [Lactococcus lactis subsp. lactis strain UC06]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATCAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGATCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGACCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGTAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CGCTTGACCAAGCAAAAAGCAAAATTAAAGATGCAAAACTAAAAGTGGGAACAGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAATGTTATCAAGACTGATCAAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATTTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCTGACGGTTATGTGTATTCTGTTTACCCGACTGTTGGAGCA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGTGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACACCGACGCCTGAAACTTCGTCAAGCACAACTTCAAGTACTTCAAGTTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(506-573)

PASTA domain (PASTA)

(434-501)

Protein kinase domain (Pkinase)

(12-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

45.84

97.767

0.448
  pknB Streptococcus mutans UA159

45.219

98.405

0.445
  stkP Streptococcus pneumoniae TIGR4

47.826

80.702

0.386
  stkP Streptococcus pneumoniae D39

47.628

80.702

0.384
  stkP Streptococcus pneumoniae R6

47.628

80.702

0.384
  stkP Streptococcus pneumoniae Rx1

47.431

80.702

0.383