Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AMD33_RS09685 Genome accession   NZ_CP012588
Coordinates   1835499..1836248 (+) Length   249 a.a.
NCBI ID   WP_014607893.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MN-BM-A01     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1830499..1841248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMD33_RS11470 - 1831051..1831221 (+) 171 WP_011680664.1 hypothetical protein -
  AMD33_RS10790 - 1831308..1831415 (+) 108 WP_011226802.1 LPXTG cell wall anchor domain-containing protein -
  AMD33_RS09670 (AMD33_09640) - 1831502..1832242 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  AMD33_RS09675 (AMD33_09645) - 1832242..1833792 (-) 1551 WP_014727298.1 ABC transporter substrate-binding protein/permease -
  AMD33_RS09680 (AMD33_09650) - 1833995..1834849 (+) 855 WP_014621086.1 undecaprenyl-diphosphate phosphatase -
  AMD33_RS09685 (AMD33_09655) mecA 1835499..1836248 (+) 750 WP_014607893.1 adaptor protein MecA Regulator
  AMD33_RS09690 (AMD33_09660) - 1836252..1837409 (+) 1158 WP_014607894.1 glycosyltransferase family 4 protein -
  AMD33_RS09695 (AMD33_09665) sufC 1837568..1838338 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  AMD33_RS09700 (AMD33_09670) sufD 1838375..1839637 (+) 1263 WP_011680669.1 Fe-S cluster assembly protein SufD -
  AMD33_RS09705 (AMD33_09675) - 1839691..1840923 (+) 1233 WP_014727299.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29109.65 Da        Isoelectric Point: 4.0624

>NTDB_id=155643 AMD33_RS09685 WP_014607893.1 1835499..1836248(+) (mecA) [Streptococcus thermophilus strain MN-BM-A01]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKTDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTGPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=155643 AMD33_RS09685 WP_014607893.1 1835499..1836248(+) (mecA) [Streptococcus thermophilus strain MN-BM-A01]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAAACAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGGGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

98.394

100

0.984
  mecA Streptococcus thermophilus LMG 18311

98.394

100

0.984
  mecA Streptococcus mutans UA159

57.787

97.992

0.566
  mecA Streptococcus pneumoniae Rx1

45.783

100

0.458
  mecA Streptococcus pneumoniae D39

45.783

100

0.458
  mecA Streptococcus pneumoniae R6

45.783

100

0.458
  mecA Streptococcus pneumoniae TIGR4

45.783

100

0.458

Multiple sequence alignment