Detailed information NTG0154194

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: WUE2121_RS00600
• Genome accession: NZ_CP012394
• Coordinates: 117715..118908 (+)
• Length: 397 a.a.
• NCBI ID: WP_002247930.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain WUE2121
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 112715..123908

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WUE2121_RS00585 (WUE2121_0104)	-	113638..114237 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
WUE2121_RS00590 (WUE2121_0105)	-	114237..116354 (+)	2118	WP_065826121.1	sensor histidine kinase	-
WUE2121_RS00595 (WUE2121_0106)	-	116347..117624 (+)	1278	WP_002247929.1	sigma-54-dependent transcriptional regulator	-
WUE2121_RS00600 (WUE2121_0107)	dprA	117715..118908 (+)	1194	WP_002247930.1	DNA-processing protein DprA	Machinery gene
WUE2121_RS00605 (WUE2121_0108)	-	118934..119395 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
WUE2121_RS00610 (WUE2121_0109)	topA	119467..121773 (+)	2307	WP_002224383.1	type I DNA topoisomerase	-
WUE2121_RS00615 (WUE2121_0110)	-	121846..122541 (-)	696	WP_002216227.1	hypothetical protein	-
WUE2121_RS00625 (WUE2121_0111)	-	123232..123609 (+)	378	WP_002247931.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42638.82 Da
• Isoelectric Point: 6.3983

>NTDB_id=154194 WUE2121_RS00600 WP_002247930.1 117715..118908(+) (dprA) [Neisseria meningitidis strain WUE2121]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAERGLIVSEFPLDTRPFAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPRLLQNEGASSYSINKGMPEKRITAVQT
ASDQLSLPEGKMPSEKTENRPVGGSILDRMGFDPVHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1194 bp

>NTDB_id=154194 WUE2121_RS00600 WP_002247930.1 117715..118908(+) (dprA) [Neisseria meningitidis strain WUE2121]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCCTCGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCCGTCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCGTTGCAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCTTATGAAATTGCCGAAAGGGGATTGATTGTCAGCGAGTTCCCTTTGGACACGCGTCCGTTTG
CAGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCACTGTCGCAAGTAACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGTTTGGCGGCAGAAATGGGGCGCGAGGTAATGGCGGTACCCGGTTCGATAGACAACCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGCCTGGACGACATCCTGAACGAATGCCCGC
GGCTCTTGCAAAATGAGGGTGCTTCGTCATATTCTATAAATAAGGGAATGCCTGAAAAGCGCATCACTGCCGTTCAGACG
GCATCCGACCAGCTGTCTCTGCCTGAAGGCAAAATGCCGTCTGAAAAGACGGAGAACCGACCCGTCGGCGGCAGTATCTT
GGACAGGATGGGTTTCGACCCAGTTCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCG
CACTGTTGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (344-390)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	94.962	100	0.95
dprA	Neisseria meningitidis MC58	94.962	100	0.95
dprA	Neisseria gonorrhoeae strain FA1090	89.673	100	0.897
dprA	Neisseria gonorrhoeae MS11	89.421	100	0.894
dprA	Vibrio cholerae strain A1552	37.845	100	0.38
dprA	Vibrio campbellii strain DS40M4	36.735	98.741	0.363