Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | DE8669_RS04830 | Genome accession | NZ_CP012391 |
| Coordinates | 924418..925017 (+) | Length | 199 a.a. |
| NCBI ID | WP_065826048.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain DE8669 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 922812..938857 | 924418..925017 | within | 0 |
Gene organization within MGE regions
Location: 922812..938857
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DE8669_RS04820 (DE8669_0903) | pilV | 922845..923456 (+) | 612 | WP_065826063.1 | type IV pilus modification protein PilV | Machinery gene |
| DE8669_RS04825 (DE8669_0904) | pilJ | 923453..924439 (+) | 987 | WP_065826047.1 | PilW family protein | Machinery gene |
| DE8669_RS04830 (DE8669_0905) | pilK | 924418..925017 (+) | 600 | WP_065826048.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| DE8669_RS04835 (DE8669_0906) | pilX | 925022..925495 (+) | 474 | WP_195182879.1 | PilX family type IV pilin | Machinery gene |
| DE8669_RS04840 (DE8669_0907) | dut | 927378..927830 (+) | 453 | WP_002229326.1 | dUTP diphosphatase | - |
| DE8669_RS04845 (DE8669_0908) | dapC | 927907..929094 (+) | 1188 | WP_065826050.1 | succinyldiaminopimelate transaminase | - |
| DE8669_RS15235 | - | 929182..929307 (+) | 126 | Protein_927 | IS5/IS1182 family transposase | - |
| DE8669_RS04850 (DE8669_0909) | yaaA | 929356..930135 (+) | 780 | WP_002235690.1 | peroxide stress protein YaaA | - |
| DE8669_RS04865 (DE8669_0910) | - | 930692..931888 (+) | 1197 | WP_002223440.1 | tyrosine-type recombinase/integrase | - |
| DE8669_RS04870 (DE8669_0911) | - | 932045..932425 (+) | 381 | WP_002220683.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| DE8669_RS04885 (DE8669_0913) | - | 932973..933329 (+) | 357 | WP_002223441.1 | DUF4760 domain-containing protein | - |
| DE8669_RS04890 (DE8669_0915) | - | 934198..935115 (+) | 918 | WP_002219437.1 | KilA-N domain-containing protein | - |
| DE8669_RS04895 (DE8669_0916) | - | 935173..935382 (-) | 210 | WP_002220687.1 | hypothetical protein | - |
| DE8669_RS04900 (DE8669_0917) | - | 935379..935519 (-) | 141 | WP_002223442.1 | hypothetical protein | - |
| DE8669_RS04905 (DE8669_0918) | - | 935519..935710 (-) | 192 | WP_002219435.1 | type ISP restriction/modification enzyme | - |
| DE8669_RS04910 (DE8669_0919) | - | 935713..936006 (-) | 294 | WP_065826051.1 | hypothetical protein | - |
| DE8669_RS04915 (DE8669_0920) | - | 936003..936263 (-) | 261 | WP_002223443.1 | NGO1622 family putative holin | - |
| DE8669_RS04920 (DE8669_0921) | - | 936298..936513 (-) | 216 | WP_002219434.1 | hypothetical protein | - |
| DE8669_RS04925 (DE8669_0922) | - | 936583..937437 (-) | 855 | WP_002219433.1 | YfdQ family protein | - |
| DE8669_RS04930 (DE8669_0923) | - | 937462..937821 (-) | 360 | WP_002219432.1 | hypothetical protein | - |
| DE8669_RS04935 (DE8669_0924) | - | 937889..938089 (-) | 201 | WP_002219431.1 | hypothetical protein | - |
| DE8669_RS04940 (DE8669_0925) | - | 938333..938758 (-) | 426 | WP_002219430.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 199 a.a. Molecular weight: 21883.68 Da Isoelectric Point: 5.3843
>NTDB_id=154075 DE8669_RS04830 WP_065826048.1 924418..925017(+) (pilK) [Neisseria meningitidis strain DE8669]
MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGELQVLDLEYDT
DSKVTFSENCEKGLCTAVNVRTNTNNGNEEVFDNIVVQGKPTVEAVKRSCTANSTNLCIDNKGTEYKKGTQSVSKPPRYI
IEYLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE
MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGELQVLDLEYDT
DSKVTFSENCEKGLCTAVNVRTNTNNGNEEVFDNIVVQGKPTVEAVKRSCTANSTNLCIDNKGTEYKKGTQSVSKPPRYI
IEYLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE
Nucleotide
Download Length: 600 bp
>NTDB_id=154075 DE8669_RS04830 WP_065826048.1 924418..925017(+) (pilK) [Neisseria meningitidis strain DE8669]
ATGCGCAAACAGAACACTTTGACGGGAATCCCGACTTCTGACGGACAGAGGGGGTTTGCACTGTTTATCGTGCTGATGGT
GATGATCGTCGTGGCTTTTTTGGTTGTAACTGCCGCGCAGTCTTACAATACCGAGCAGCGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTGGCCGAGGCGGCTTTGCGGGAAGGCGAACTTCAGGTTTTGGATTTGGAATATGATACG
GACAGTAAGGTTACATTTAGCGAAAACTGTGAAAAAGGTCTGTGTACCGCAGTGAATGTGCGGACAAATACAAATAATGG
TAATGAAGAGGTTTTTGACAATATCGTGGTGCAAGGCAAGCCCACCGTTGAGGCGGTGAAGCGTTCTTGCACTGCAAATT
CTACCAACCTGTGCATTGACAATAAAGGGACGGAATATAAGAAAGGCACGCAAAGCGTCAGCAAACCACCACGCTATATT
ATCGAATATTTGGGCGTGAAGAACGGAGAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAATACCGT
GGTCGTCCTTCAATCTTATGTAAGCAATAATGATGAGTAA
ATGCGCAAACAGAACACTTTGACGGGAATCCCGACTTCTGACGGACAGAGGGGGTTTGCACTGTTTATCGTGCTGATGGT
GATGATCGTCGTGGCTTTTTTGGTTGTAACTGCCGCGCAGTCTTACAATACCGAGCAGCGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTGGCCGAGGCGGCTTTGCGGGAAGGCGAACTTCAGGTTTTGGATTTGGAATATGATACG
GACAGTAAGGTTACATTTAGCGAAAACTGTGAAAAAGGTCTGTGTACCGCAGTGAATGTGCGGACAAATACAAATAATGG
TAATGAAGAGGTTTTTGACAATATCGTGGTGCAAGGCAAGCCCACCGTTGAGGCGGTGAAGCGTTCTTGCACTGCAAATT
CTACCAACCTGTGCATTGACAATAAAGGGACGGAATATAAGAAAGGCACGCAAAGCGTCAGCAAACCACCACGCTATATT
ATCGAATATTTGGGCGTGAAGAACGGAGAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAATACCGT
GGTCGTCCTTCAATCTTATGTAAGCAATAATGATGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
88.177 |
100 |
0.899 |