Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   DE8669_RS04815 Genome accession   NZ_CP012391
Coordinates   922147..922815 (+) Length   222 a.a.
NCBI ID   WP_061696530.1    Uniprot ID   -
Organism   Neisseria meningitidis strain DE8669     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 922812..938857 922147..922815 flank -3


Gene organization within MGE regions


Location: 922147..938857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8669_RS04815 (DE8669_0902) pilH 922147..922815 (+) 669 WP_061696530.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  DE8669_RS04820 (DE8669_0903) pilV 922845..923456 (+) 612 WP_065826063.1 type IV pilus modification protein PilV Machinery gene
  DE8669_RS04825 (DE8669_0904) pilJ 923453..924439 (+) 987 WP_065826047.1 PilW family protein Machinery gene
  DE8669_RS04830 (DE8669_0905) pilK 924418..925017 (+) 600 WP_065826048.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  DE8669_RS04835 (DE8669_0906) pilX 925022..925495 (+) 474 WP_195182879.1 PilX family type IV pilin Machinery gene
  DE8669_RS04840 (DE8669_0907) dut 927378..927830 (+) 453 WP_002229326.1 dUTP diphosphatase -
  DE8669_RS04845 (DE8669_0908) dapC 927907..929094 (+) 1188 WP_065826050.1 succinyldiaminopimelate transaminase -
  DE8669_RS15235 - 929182..929307 (+) 126 Protein_927 IS5/IS1182 family transposase -
  DE8669_RS04850 (DE8669_0909) yaaA 929356..930135 (+) 780 WP_002235690.1 peroxide stress protein YaaA -
  DE8669_RS04865 (DE8669_0910) - 930692..931888 (+) 1197 WP_002223440.1 tyrosine-type recombinase/integrase -
  DE8669_RS04870 (DE8669_0911) - 932045..932425 (+) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  DE8669_RS04885 (DE8669_0913) - 932973..933329 (+) 357 WP_002223441.1 DUF4760 domain-containing protein -
  DE8669_RS04890 (DE8669_0915) - 934198..935115 (+) 918 WP_002219437.1 KilA-N domain-containing protein -
  DE8669_RS04895 (DE8669_0916) - 935173..935382 (-) 210 WP_002220687.1 hypothetical protein -
  DE8669_RS04900 (DE8669_0917) - 935379..935519 (-) 141 WP_002223442.1 hypothetical protein -
  DE8669_RS04905 (DE8669_0918) - 935519..935710 (-) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  DE8669_RS04910 (DE8669_0919) - 935713..936006 (-) 294 WP_065826051.1 hypothetical protein -
  DE8669_RS04915 (DE8669_0920) - 936003..936263 (-) 261 WP_002223443.1 NGO1622 family putative holin -
  DE8669_RS04920 (DE8669_0921) - 936298..936513 (-) 216 WP_002219434.1 hypothetical protein -
  DE8669_RS04925 (DE8669_0922) - 936583..937437 (-) 855 WP_002219433.1 YfdQ family protein -
  DE8669_RS04930 (DE8669_0923) - 937462..937821 (-) 360 WP_002219432.1 hypothetical protein -
  DE8669_RS04935 (DE8669_0924) - 937889..938089 (-) 201 WP_002219431.1 hypothetical protein -
  DE8669_RS04940 (DE8669_0925) - 938333..938758 (-) 426 WP_002219430.1 hypothetical protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24837.30 Da        Isoelectric Point: 9.5824

>NTDB_id=154072 DE8669_RS04815 WP_061696530.1 922147..922815(+) (pilH) [Neisseria meningitidis strain DE8669]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTAN
NKCDSGKKEQGMLAFGDKNGNKGYDNDTADVLLRSVVLNDDINDKRINYAFNHIAFGKTQPTADRVVWTFNQNGTFGYTN
DQHLTSQSSFSYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=154072 DE8669_RS04815 WP_061696530.1 922147..922815(+) (pilH) [Neisseria meningitidis strain DE8669]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGGCCAAC
AATAAATGTGACTCCGGCAAGAAGGAGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGGATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTAAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAC
GACCAGCATCTTACAAGCCAATCCAGCTTTTCTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

84.163

99.55

0.838

Multiple sequence alignment