Detailed information    

insolico Bioinformatically predicted

Overview

Name   recB   Type   Machinery gene
Locus tag   DE8669_RS04305 Genome accession   NZ_CP012391
Coordinates   824654..828268 (-) Length   1204 a.a.
NCBI ID   WP_014581153.1    Uniprot ID   A0A425B4Y2
Organism   Neisseria meningitidis strain DE8669     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 819654..833268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8669_RS04285 (DE8669_0808) hemE 820832..821896 (+) 1065 WP_002219525.1 uroporphyrinogen decarboxylase -
  DE8669_RS04290 (DE8669_0809) radA 822085..823464 (+) 1380 WP_002223905.1 DNA repair protein RadA Machinery gene
  DE8669_RS04295 (DE8669_0810) - 823535..824014 (-) 480 WP_002219523.1 DUF302 domain-containing protein -
  DE8669_RS04300 (DE8669_0811) - 824256..824615 (-) 360 WP_002219522.1 rhodanese-like domain-containing protein -
  DE8669_RS04305 (DE8669_0812) recB 824654..828268 (-) 3615 WP_014581153.1 exodeoxyribonuclease V subunit beta Machinery gene
  DE8669_RS04310 (DE8669_0813) - 828348..829256 (-) 909 WP_002217584.1 Dyp-type peroxidase -
  DE8669_RS04315 (DE8669_0814) - 829541..830368 (+) 828 WP_002213986.1 amino acid ABC transporter substrate-binding protein -
  DE8669_RS04320 (DE8669_0815) - 830358..831074 (+) 717 WP_002223904.1 amino acid ABC transporter permease -
  DE8669_RS04325 (DE8669_0816) - 831084..831839 (+) 756 WP_002213983.1 amino acid ABC transporter ATP-binding protein -
  DE8669_RS04330 (DE8669_0817) - 831859..833241 (-) 1383 WP_002219518.1 phosphomannomutase/phosphoglucomutase -

Sequence

Protein


Download         Length: 1204 a.a.        Molecular weight: 134418.80 Da        Isoelectric Point: 5.9247

>NTDB_id=154071 DE8669_RS04305 WP_014581153.1 824654..828268(-) (recB) [Neisseria meningitidis strain DE8669]
MSAPIQAFDPLTVPIAGTNLIEASAGTGKTYGIAALFTRLIVLEQKNVERVLVVTFTKAATAELKTRLRARLDDVLQVLE
SKEIAKLGDDTLSDGIAAYCAEHHKGDTFLPALLKQALQKEGRTRLIVRLKAAIGQFDNAAIYTIHGFCQRILRDYAFLC
QAPFDVELTEEDGDRLLIPAQDFWRERVSNDPVLAALAFKRKAVPQTVLAQISRYLSRPYLNFRRPQADLKQAQRNAETS
WQTICRLLPELEAGFWRIHPDLNGNSYRKNSFGNLFKELAQKSAAGQLPFLDKDTHDRLLKLASDKLEAALKKGKTPDAA
AFAELQKLADFGRDLNALEEAEEATMIRLQLDLIGYLNRSLAEMKKSRRERGFDDLLLDVHTALTDNPHAETLARAVAEN
WETALIDEFQDTDPLQYEIFQKIFIAQNRPLFLVGDPKQAIYSFRGADIYAYLQAAGDARHRYTLATNYRSHAALIGSIG
ALFRLKERPFVLENIGYSEVGAARAESRLSPERPAVQVRWLHENDNEKANKDVLRRRAADYCADEIAHALNEAAGGRLNF
KGCPLQSGDIAVLVRTHNEAVMVSAALKKRQVQSVLLSRESVFASPEAAALSALIGFWLEPRRAGTLRFVLTSGIFGYDA
QQLHDFNQNESEILHWAESARTALDNWNQYGIFAAMQQFSQTHGIETRLLSRNNGRSLTNYFQLLELLAAEDAQNRNPAA
LHKWLRDQISLAGNNSGDNRAIRLESDEDLVKIVTMHASKGLQYPLVYCPFAWDAQDTGPSDWQILHQSANRTELLAKAQ
LSEDEQKQYADEEMAERLRLLYVALTRAEEQLNIYAAYSTNTADNPLAYLIEGSPQDSRETVRRAYACEKDGIAMLKRNW
RRVADNAPSGTNFAFTENAPPPAAYRSNAGQTAEFAANSIPERGFRFVRHTSFTALSRHTQTPDGGEEDACPSLDAAETS
VPAMPSETPTASDGISIHDFPKGTQAGLCLHEILEDFKFGQAAAGQETLIADKLKKYGFEEIWLPAVAEMAEACRKTPLT
GAYDLSDISPECRCPEMGFTLHTEDFSLKRLRDWFARDDIRLPEVCRAAAETLDFHTVNGFLNGFVDMVCQDPDGNICVI
DYKSNHLGTDASAYTQQAMDEAVAHHHYYLQALIYAVAAARYFKLRGQPPAAVSVRYLFLRGLDGKGGGVWRWDIDAAAL
EQIK

Nucleotide


Download         Length: 3615 bp        

>NTDB_id=154071 DE8669_RS04305 WP_014581153.1 824654..828268(-) (recB) [Neisseria meningitidis strain DE8669]
ATGTCTGCACCCATCCAAGCATTTGACCCGCTGACCGTCCCCATTGCCGGCACCAACCTGATTGAGGCCTCTGCCGGCAC
CGGCAAAACCTACGGCATCGCCGCCCTGTTTACGCGCCTGATCGTATTGGAACAAAAAAACGTCGAGCGCGTATTGGTCG
TTACCTTCACCAAAGCCGCCACCGCCGAGTTGAAAACACGCCTGCGCGCACGTTTGGACGATGTGTTGCAGGTTTTAGAA
AGTAAAGAAATTGCCAAACTTGGAGACGACACGCTTTCAGACGGCATCGCCGCCTACTGCGCCGAACACCACAAAGGCGA
CACCTTCCTGCCCGCACTCTTAAAACAGGCTTTGCAAAAAGAGGGCCGGACGCGTCTGATTGTCCGCCTCAAGGCCGCCA
TCGGGCAATTCGACAACGCCGCCATCTATACCATCCACGGCTTCTGCCAACGTATCCTGCGCGACTACGCCTTCTTGTGC
CAAGCACCGTTCGATGTCGAACTGACCGAAGAAGACGGCGACCGCCTGCTTATCCCGGCGCAAGATTTTTGGCGGGAACG
CGTCAGCAATGATCCGGTGCTTGCCGCATTGGCGTTTAAACGCAAAGCTGTGCCGCAAACCGTCCTTGCCCAAATTTCGC
GCTATCTTTCCCGCCCGTACCTGAATTTCCGCCGTCCGCAGGCGGATTTGAAACAGGCGCAGCGCAACGCCGAAACCTCA
TGGCAAACCATCTGCCGCCTGCTGCCCGAGCTGGAAGCCGGCTTTTGGCGCATCCATCCCGACCTCAACGGCAACAGTTA
CCGCAAAAACAGCTTCGGCAACCTTTTTAAAGAACTGGCACAAAAATCCGCCGCCGGACAACTGCCCTTTCTGGACAAAG
ACACGCACGACAGACTCTTGAAACTTGCGTCCGACAAACTCGAAGCCGCCCTTAAAAAAGGCAAAACGCCCGATGCGGCA
GCATTTGCCGAATTGCAGAAACTGGCAGACTTCGGGCGCGATTTGAACGCACTCGAAGAAGCGGAAGAAGCAACAATGAT
CCGGCTGCAACTGGATTTAATCGGATACCTCAACCGCAGCCTTGCCGAGATGAAAAAATCGCGCCGCGAACGCGGTTTCG
ACGACCTGCTGCTCGATGTCCACACCGCGCTGACCGACAATCCGCACGCCGAAACCCTCGCCCGCGCCGTTGCCGAAAAC
TGGGAAACCGCGCTGATCGACGAGTTCCAAGACACCGACCCGCTGCAATATGAAATCTTCCAAAAGATTTTCATTGCCCA
AAACCGCCCACTGTTTCTCGTCGGCGATCCCAAACAGGCGATTTACAGCTTTCGCGGAGCGGACATTTACGCCTACCTGC
AAGCCGCCGGAGACGCGCGGCACCGCTACACGCTCGCCACCAACTACCGCAGCCACGCCGCGCTTATCGGCAGCATAGGC
GCGCTGTTCCGCCTCAAAGAACGCCCGTTCGTTTTGGAAAACATCGGCTATTCGGAAGTCGGTGCGGCGCGTGCCGAAAG
CAGGTTGTCCCCCGAACGTCCTGCCGTACAGGTTCGTTGGCTGCACGAAAACGACAATGAAAAAGCCAACAAAGACGTTT
TGCGCCGCCGTGCCGCCGACTATTGCGCCGACGAAATCGCCCACGCGCTCAACGAAGCCGCCGGAGGCCGTCTGAATTTC
AAAGGCTGCCCGTTGCAGTCGGGCGATATTGCCGTGCTGGTACGCACGCACAACGAGGCGGTGATGGTTTCCGCCGCCCT
GAAAAAACGGCAGGTGCAAAGCGTCCTGCTTTCGCGCGAATCTGTGTTCGCCTCGCCCGAAGCCGCCGCCCTGTCCGCAC
TCATCGGCTTCTGGCTCGAACCGCGCCGCGCCGGAACGCTGCGCTTTGTCCTGACAAGCGGCATATTCGGTTATGACGCG
CAGCAATTGCACGACTTCAACCAAAACGAAAGCGAGATTTTGCATTGGGCGGAATCTGCCCGAACCGCACTCGACAACTG
GAATCAATACGGCATTTTCGCCGCTATGCAGCAATTTTCCCAAACACACGGCATCGAAACGCGCCTCTTAAGCCGGAACA
ACGGGCGCAGCCTGACCAACTATTTCCAACTGCTCGAACTGCTTGCCGCCGAAGACGCGCAAAACCGCAACCCAGCCGCG
CTGCACAAATGGTTGCGCGACCAAATCAGCCTGGCCGGCAACAACAGCGGCGACAACCGCGCCATCCGTCTGGAAAGCGA
CGAAGATTTGGTCAAAATCGTTACCATGCACGCCTCGAAAGGTTTGCAGTATCCGCTGGTGTACTGCCCGTTTGCGTGGG
ACGCGCAAGATACCGGGCCGTCCGACTGGCAAATCCTCCACCAAAGCGCAAACCGAACCGAACTGTTGGCAAAGGCGCAA
CTGTCGGAAGACGAACAGAAACAATACGCCGATGAAGAAATGGCGGAACGCCTGCGCCTGCTTTATGTCGCACTGACGCG
TGCCGAGGAACAGCTCAACATCTACGCCGCGTACTCCACCAATACTGCCGACAACCCCCTCGCCTACCTGATTGAAGGCT
CGCCCCAAGACAGCCGTGAAACCGTCCGCCGTGCCTATGCGTGTGAAAAAGACGGCATCGCGATGCTCAAACGCAACTGG
CGGCGCGTGGCGGACAACGCCCCTTCCGGCACAAATTTCGCCTTCACCGAAAATGCGCCGCCCCCTGCCGCCTATCGCAG
CAACGCCGGTCAAACCGCCGAATTTGCCGCAAACAGCATTCCCGAACGCGGATTCCGATTTGTCCGCCACACTAGCTTTA
CCGCCTTAAGCCGCCATACCCAAACGCCCGACGGCGGCGAAGAAGATGCCTGCCCGTCCTTGGATGCCGCCGAAACCTCG
GTGCCGGCGATGCCGTCTGAAACGCCGACGGCTTCAGACGGCATATCGATACACGATTTTCCGAAAGGCACGCAGGCGGG
GCTGTGCCTGCACGAAATTCTTGAAGATTTCAAATTCGGACAAGCAGCCGCCGGACAGGAAACCCTCATTGCCGACAAGC
TGAAAAAATACGGTTTTGAAGAAATATGGCTGCCCGCCGTTGCCGAAATGGCGGAAGCCTGCCGCAAAACGCCGCTGACG
GGGGCATACGACCTGTCCGACATCTCACCCGAGTGCCGCTGTCCCGAAATGGGCTTTACCCTCCACACCGAAGACTTCAG
CCTCAAACGCCTGCGCGACTGGTTTGCCCGCGACGACATCAGGCTGCCCGAAGTCTGCCGTGCCGCTGCCGAAACGCTCG
ACTTCCACACCGTCAACGGCTTTTTAAACGGCTTTGTCGATATGGTCTGCCAAGACCCCGACGGCAATATCTGCGTCATC
GACTACAAATCAAACCACCTCGGTACGGACGCATCCGCCTACACGCAACAGGCAATGGACGAAGCCGTCGCACACCACCA
CTATTACCTTCAGGCACTGATTTACGCCGTTGCCGCCGCACGCTACTTCAAGCTGCGCGGACAACCGCCCGCCGCCGTTT
CCGTCCGCTACCTGTTTTTGCGCGGATTGGATGGCAAAGGCGGCGGCGTTTGGCGTTGGGACATAGATGCCGCCGCTTTG
GAACAGATAAAATAA

Domains

Predicted by InterproScan.

UvrD-like helicase C-terminal domain (UvrD_C)

(463-835)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1068-1182)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(15-457)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A425B4Y2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recB Neisseria gonorrhoeae strain FA1090

94.435

100

0.944

Multiple sequence alignment