Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   DE8669_RS00100 Genome accession   NZ_CP012391
Coordinates   17412..17921 (-) Length   169 a.a.
NCBI ID   WP_065826035.1    Uniprot ID   -
Organism   Neisseria meningitidis strain DE8669     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 12412..22921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8669_RS00085 (DE8669_0017) gnd 13224..14672 (-) 1449 WP_002228813.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  DE8669_RS00095 (DE8669_0018) lpxC 15608..16531 (-) 924 WP_002216134.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  DE8669_RS00100 (DE8669_0019) pilE 17412..17921 (-) 510 WP_065826035.1 pilin Machinery gene
  DE8669_RS00105 (DE8669_0021) - 18832..19254 (-) 423 Protein_19 pilin -
  DE8669_RS00110 (DE8669_0023) - 19620..19958 (-) 339 Protein_20 pilin -
  DE8669_RS00115 (DE8669_0024) - 20297..20686 (-) 390 Protein_21 pilin -
  DE8669_RS00120 (DE8669_0025) - 20916..21347 (-) 432 Protein_22 pilin -
  DE8669_RS00125 (DE8669_0026) - 21531..21956 (-) 426 Protein_23 pilin -
  DE8669_RS00130 (DE8669_0027) - 22297..22686 (-) 390 Protein_24 pilin -

Sequence

Protein


Download         Length: 169 a.a.        Molecular weight: 17915.47 Da        Isoelectric Point: 8.9679

>NTDB_id=154052 DE8669_RS00100 WP_065826035.1 17412..17921(-) (pilE) [Neisseria meningitidis strain DE8669]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGIWPGDNSSAGVATSSEIK
GKYVEKVEVAKGVITATMLSTGVNKEIQGKKLSLWAKRQAGSVKWFCGQPVQRAKADADAVTAAANGKTADNINTKHLPS
TCRDDSSTS

Nucleotide


Download         Length: 510 bp        

>NTDB_id=154052 DE8669_RS00100 WP_065826035.1 17412..17921(-) (pilE) [Neisseria meningitidis strain DE8669]
ATGAACACCCTTCAAAAAGGTTTTACCCTTATCGAGCTGATGATTGTGATTGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCTGCTTATCAAGACTACACAGCCCGCGCACAAGTTTCCGAAGCCATCCTTTTGGCTGAAGGTCAAAAATCAGCCG
TCACCGAGTATTACCTGAATCACGGCATATGGCCCGGCGACAACAGTTCTGCCGGCGTGGCAACCTCCTCTGAAATCAAA
GGCAAATATGTTGAGAAAGTTGAAGTCGCAAAAGGCGTCATTACCGCCACAATGCTTTCAACCGGCGTAAACAAAGAAAT
CCAAGGCAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGCCGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTCAGCGCG
CCAAAGCCGACGCCGACGCCGTTACCGCCGCCGCCAACGGCAAGACCGCCGACAACATCAACACCAAGCACCTGCCGTCA
ACCTGCCGCGATGATTCATCTACCAGCTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-163)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

81.657

100

0.817
  pilE Neisseria gonorrhoeae MS11

77.976

99.408

0.775
  pilE Neisseria elongata subsp. glycolytica ATCC 29315

35.938

100

0.408
  pilA/pilA1 Eikenella corrodens VA1

36.158

100

0.379
  comP Acinetobacter baylyi ADP1

37.5

99.408

0.373

Multiple sequence alignment