Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V471_RS04445 Genome accession   NZ_CP015283
Coordinates   847278..848015 (-) Length   245 a.a.
NCBI ID   WP_002883766.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 842278..853015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS04425 (V471_04360) - 843401..844378 (+) 978 WP_232326838.1 HlyD family efflux transporter periplasmic adaptor subunit -
  V471_RS11300 comD/blpH 844466..844636 (-) 171 WP_157108264.1 GHKL domain-containing protein Regulator
  V471_RS04430 (V471_04365) - 844739..845125 (-) 387 WP_045768432.1 IS110 family transposase -
  V471_RS04435 (V471_04370) - 845145..845906 (-) 762 WP_049529073.1 IS110 family transposase -
  V471_RS11065 comD/comD1 846115..846624 (-) 510 WP_198166466.1 GHKL domain-containing protein Regulator
  V471_RS04445 (V471_04380) comE/blpR 847278..848015 (-) 738 WP_002883766.1 LytR/AlgR family response regulator transcription factor Regulator
  V471_RS04450 (V471_04385) - 848744..849556 (-) 813 WP_002889987.1 HAD family hydrolase -
  V471_RS04455 (V471_04390) - 849765..851186 (+) 1422 WP_002883789.1 NCS2 family permease -
  V471_RS04460 (V471_04395) tsaE 851462..851905 (+) 444 WP_084871137.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  V471_RS04465 (V471_04400) - 851898..852419 (+) 522 WP_002886613.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28536.61 Da        Isoelectric Point: 7.0641

>NTDB_id=153153 V471_RS04445 WP_002883766.1 847278..848015(-) (comE/blpR) [Streptococcus salivarius strain ATCC 25975]
MDIYILEDNIIQQGRLEQALDKALRSYGETLDCVQTFEQSNQLLEYIKPANHQQLFFLDIEIKGKEKEGLHLGQTIRNKL
PDAHIVFVTSHSEFMPLTFSYQLFALDYIDKNLDEDSFQSKVAIALSYVAKQSIKKEEKFSFHSGTDHIDLSYDRLLYIE
TSAKRHYVILHGSHSIFEFRANISDLANANPKLFRCHRSYLINPDKLVRLNKTKREIEMSDGTNCLVSRRHIKAVLAFMY
EDKKI

Nucleotide


Download         Length: 738 bp        

>NTDB_id=153153 V471_RS04445 WP_002883766.1 847278..848015(-) (comE/blpR) [Streptococcus salivarius strain ATCC 25975]
ATGGATATCTACATTTTAGAGGACAACATAATACAGCAAGGTAGATTGGAACAGGCTCTGGATAAGGCTCTCAGATCCTA
TGGTGAGACACTAGACTGTGTCCAGACCTTTGAACAATCCAACCAACTTCTGGAATATATAAAGCCAGCCAACCATCAAC
AACTCTTTTTCTTGGATATTGAGATTAAAGGGAAAGAAAAAGAAGGACTCCATTTGGGACAAACCATCCGAAACAAACTA
CCAGATGCTCATATTGTCTTTGTAACCTCCCACTCAGAGTTTATGCCCTTAACTTTTAGTTACCAACTCTTTGCCCTAGA
CTATATCGACAAAAATCTAGATGAAGATTCTTTTCAATCAAAGGTCGCGATAGCCCTATCCTATGTCGCTAAGCAAAGTA
TAAAAAAAGAGGAAAAGTTCTCTTTTCATTCTGGAACCGACCATATCGATCTCTCCTATGACCGTTTGCTTTATATTGAA
ACATCTGCTAAAAGGCACTATGTTATCTTACACGGTTCCCATAGCATTTTTGAGTTTCGAGCCAATATCTCAGACTTAGC
TAATGCCAATCCTAAGCTCTTCCGCTGTCATCGCTCCTACCTAATCAACCCTGACAAGTTGGTACGTCTCAATAAGACCA
AACGCGAAATCGAAATGTCAGACGGCACTAACTGTCTGGTATCTCGTAGACATATCAAGGCAGTCTTAGCCTTTATGTAT
GAGGATAAGAAGATATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-235)

Response regulator receiver domain (Response_reg)

(4-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

37.247

100

0.376
  comE/comE2 Streptococcus equinus JB1

36.777

98.776

0.363
  comE/comE1 Streptococcus equinus JB1

36.929

98.367

0.363