Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   NX99_RS07830 Genome accession   NZ_CP015282
Coordinates   1695827..1696570 (+) Length   247 a.a.
NCBI ID   WP_002885796.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1690827..1701570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS07810 (NX99_07670) - 1690926..1692233 (+) 1308 WP_002885760.1 GHKL domain-containing protein -
  NX99_RS07815 (NX99_07675) - 1692293..1693183 (+) 891 WP_038676823.1 hypothetical protein -
  NX99_RS07820 (NX99_07680) - 1693205..1694485 (+) 1281 WP_038676820.1 hypothetical protein -
  NX99_RS07825 (NX99_07685) - 1694509..1695825 (+) 1317 WP_038676818.1 GHKL domain-containing protein -
  NX99_RS07830 (NX99_07690) comE/blpR 1695827..1696570 (+) 744 WP_002885796.1 response regulator transcription factor Regulator
  NX99_RS07835 (NX99_07695) - 1697516..1698715 (+) 1200 WP_002885646.1 argininosuccinate synthase -
  NX99_RS07840 (NX99_07700) argH 1699042..1700427 (+) 1386 WP_048790873.1 argininosuccinate lyase -
  NX99_RS07845 (NX99_07705) rnpA 1700512..1700847 (+) 336 WP_002891957.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28536.83 Da        Isoelectric Point: 6.7589

>NTDB_id=153064 NX99_RS07830 WP_002885796.1 1695827..1696570(+) (comE/blpR) [Streptococcus salivarius strain ATCC 27945]
MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY
FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVKEH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=153064 NX99_RS07830 WP_002885796.1 1695827..1696570(+) (comE/blpR) [Streptococcus salivarius strain ATCC 27945]
ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGCATTAGCGACATCATCCGAGAATTGGTTTCAGAGGG
CACGTTTTCTGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAACGAGAAGGGCAACCATC
AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT
GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATCAGTTTTAAATACAAGGTTTCTGCACTAGA
TTTCATTGATAAGACAGTTTCTAATGCAGAATTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG
GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT
TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTAATTACCAAAACAGAGCGTCTGGAGTTTTATGCCAATCTTGGAGA
TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA
AGACTCAGTTGATGATTTACTTTGAAAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCCTGCTTAAAAAA
TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.5

97.166

0.462
  comE/comE2 Streptococcus equinus JB1

42.857

99.19

0.425
  comE/comE1 Streptococcus equinus JB1

40.496

97.976

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.402

100

0.385
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.402

100

0.385