Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AC806_RS01140 Genome accession   NZ_CP012047
Coordinates   247657..248925 (-) Length   422 a.a.
NCBI ID   WP_069028569.1    Uniprot ID   -
Organism   Tetragenococcus halophilus strain MJ4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 242657..253925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AC806_RS01110 (AC806_01120) pepV 242740..244152 (+) 1413 WP_069028567.1 dipeptidase PepV -
  AC806_RS01115 (AC806_01125) - 244261..244602 (-) 342 WP_061840694.1 hypothetical protein -
  AC806_RS11600 - 244694..244846 (-) 153 Protein_226 aminoglycoside 6-adenylyltransferase -
  AC806_RS01120 (AC806_01130) pepA 244990..246066 (+) 1077 WP_069028568.1 glutamyl aminopeptidase -
  AC806_RS01125 (AC806_01135) - 246154..246468 (+) 315 WP_061840692.1 thioredoxin family protein -
  AC806_RS01130 (AC806_01140) - 246491..246949 (+) 459 WP_014123648.1 universal stress protein -
  AC806_RS01135 (AC806_01145) ytpR 247002..247613 (+) 612 WP_014123649.1 YtpR family tRNA-binding protein -
  AC806_RS01140 (AC806_01150) htrA 247657..248925 (-) 1269 WP_069028569.1 S1C family serine protease Regulator
  AC806_RS01145 (AC806_01155) rlmH 249267..249746 (+) 480 WP_069028570.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AC806_RS01150 (AC806_01160) - 249790..250317 (+) 528 WP_061840689.1 AAA family ATPase -
  AC806_RS01155 (AC806_01165) msrA 250544..251371 (+) 828 WP_069028571.1 peptide-methionine (S)-S-oxide reductase MsrA -
  AC806_RS01160 (AC806_01170) - 251466..251945 (+) 480 WP_069028572.1 C-GCAxxG-C-C family protein -
  AC806_RS01165 (AC806_01175) - 251949..252881 (+) 933 WP_069028573.1 TDT family transporter -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 44042.90 Da        Isoelectric Point: 3.7734

>NTDB_id=150827 AC806_RS01140 WP_069028569.1 247657..248925(-) (htrA) [Tetragenococcus halophilus strain MJ4]
MAKKNVTPDSKKGGWIKKFGIGLLGGLIGGLLVIGGFYYFSNGNPFQTNEATSSSGVTDNNDDVQVSDVKVDADSDTTDA
VENVQNAVVSVINLQNSSPQESGGIFGTEQPEGNSEDDEEPAGEGSGVIYKEDGGDAYIVTNNHVVAGQSGLEVVMADGS
REQAELVGTDAYTDLAVLKISSDNVDTVATFGDSDELQVGEPAIAIGSPLGSDYANSVTQGIISSVNRLVSRKNESGEDV
STNAIQTDAAINPGNSGGPLVNAGGQVVGINSSKIASSGQAGVSVEGMGFAIPSNDVTDIINELEENGEIARPALGISML
DLNTIPTEQRQRVLQIPEDVENGVVVENPGDGTPASDAGLEQYDVITKVDDKEIKDSTELRAALYEKSVGDTLKLTFYRQ
DDAQSVNVKLSEDQSIIESNNE

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=150827 AC806_RS01140 WP_069028569.1 247657..248925(-) (htrA) [Tetragenococcus halophilus strain MJ4]
ATGGCAAAAAAGAATGTAACACCTGATTCTAAAAAAGGCGGGTGGATTAAAAAATTCGGAATTGGCCTATTAGGTGGATT
AATAGGCGGGTTACTTGTCATTGGCGGCTTTTATTATTTTTCTAATGGTAACCCATTTCAAACAAATGAAGCAACTTCTT
CATCTGGCGTAACAGATAATAACGACGACGTACAGGTCAGTGATGTTAAAGTTGATGCCGATAGTGATACCACAGACGCT
GTAGAAAATGTACAAAATGCTGTCGTTTCAGTGATCAATTTACAAAACTCTTCTCCTCAAGAAAGCGGAGGTATTTTTGG
CACCGAGCAACCAGAAGGCAACTCTGAAGACGACGAGGAGCCAGCTGGTGAAGGTAGTGGTGTGATTTACAAAGAAGATG
GCGGCGATGCCTACATTGTAACAAATAATCACGTAGTTGCCGGACAAAGTGGCTTAGAAGTAGTTATGGCAGACGGTAGT
AGAGAACAAGCAGAATTAGTAGGTACTGATGCTTATACTGACTTAGCCGTATTAAAAATTTCTTCTGATAATGTAGACAC
AGTAGCTACATTCGGTGATTCTGATGAATTACAAGTAGGTGAACCAGCGATCGCTATTGGTTCTCCTCTAGGTTCTGATT
ATGCTAATTCAGTAACCCAAGGAATTATTTCTTCAGTCAATCGTTTAGTATCCAGAAAAAATGAATCTGGCGAAGATGTG
AGCACAAATGCTATTCAAACGGACGCTGCAATCAACCCAGGAAATTCTGGCGGGCCATTGGTCAATGCTGGTGGACAAGT
TGTTGGAATTAACTCCAGTAAAATTGCTAGTTCCGGACAAGCTGGCGTAAGTGTTGAAGGCATGGGCTTTGCTATTCCAA
GTAATGATGTAACAGATATTATTAATGAATTGGAAGAAAATGGTGAAATTGCTCGTCCAGCGTTAGGCATCTCCATGCTT
GATTTAAATACCATTCCTACAGAACAAAGACAACGTGTTTTACAAATCCCTGAGGATGTAGAAAACGGCGTTGTTGTAGA
AAACCCTGGCGATGGCACACCAGCAAGTGATGCAGGATTAGAACAATATGATGTTATTACAAAAGTTGACGATAAAGAAA
TAAAAGATTCTACTGAGCTACGTGCCGCTTTATATGAAAAATCAGTAGGAGATACTTTGAAATTGACTTTTTATCGACAA
GATGACGCACAATCTGTAAATGTTAAACTATCAGAAGATCAATCAATCATTGAAAGCAACAACGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(313-410)

Peptidase family M50 (Peptidase_M50)

(317-414)

Trypsin-like peptidase domain (Trypsin_2)

(125-270)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

57.821

84.834

0.491
  htrA Streptococcus mitis NCTC 12261

50.513

92.417

0.467
  htrA Streptococcus pneumoniae Rx1

50

92.417

0.462
  htrA Streptococcus pneumoniae D39

50

92.417

0.462
  htrA Streptococcus pneumoniae R6

50

92.417

0.462
  htrA Streptococcus pneumoniae TIGR4

50

92.417

0.462
  htrA Streptococcus gordonii str. Challis substr. CH1

49.49

92.891

0.46

Multiple sequence alignment