Detailed information NTG0150596

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: WX60_RS06505
• Genome accession: NZ_CP012027
• Coordinates: 1197546..1198406 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FA6140
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1192546..1203406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WX60_RS06490 (WX60_01236)	dapD	1193056..1193877 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
WX60_RS06495 (WX60_01237)	pgi	1194087..1195730 (-)	1644	WP_003697594.1	glucose-6-phosphate isomerase	-
WX60_RS06500 (WX60_01238)	pilG	1196240..1197472 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
WX60_RS06505 (WX60_01239)	pilD	1197546..1198406 (+)	861	WP_003689814.1	A24 family peptidase	Machinery gene
WX60_RS06510 (WX60_01240)	coaE	1198403..1199035 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
WX60_RS06515 (WX60_01241)	-	1199028..1199237 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
WX60_RS06520 (WX60_01242)	pilF	1199323..1200999 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
WX60_RS06530 (WX60_01244)	-	1201337..1201783 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
WX60_RS06535 (WX60_01245)	-	1201787..1202761 (-)	975	WP_010360822.1	polyprenyl synthetase family protein	-
WX60_RS06540 (WX60_01246)	rplU	1202985..1203293 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=150596 WX60_RS06505 WP_003689814.1 1197546..1198406(+) (pilD) [Neisseria gonorrhoeae strain FA6140]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=150596 WX60_RS06505 WP_003689814.1 1197546..1198406(+) (pilD) [Neisseria gonorrhoeae strain FA6140]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441