Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NH16_RS03060 Genome accession   NZ_CP012009
Coordinates   599305..600444 (-) Length   379 a.a.
NCBI ID   WP_048592489.1    Uniprot ID   -
Organism   Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 594305..605444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NH16_RS03040 (NH16_03035) - 594681..595346 (+) 666 WP_010285559.1 NAD(P)H-hydrate epimerase -
  NH16_RS03045 (NH16_03040) - 595431..595883 (-) 453 WP_048592487.1 Rrf2 family transcriptional regulator -
  NH16_RS03050 (NH16_03045) - 595937..598102 (-) 2166 WP_048592488.1 YhgE/Pip domain-containing protein -
  NH16_RS03055 (NH16_03050) rlmH 598196..598675 (-) 480 WP_002815697.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  NH16_RS03060 (NH16_03055) htrA 599305..600444 (-) 1140 WP_048592489.1 trypsin-like peptidase domain-containing protein Regulator
  NH16_RS03065 (NH16_03060) yycI 600505..601308 (-) 804 WP_010289058.1 two-component system regulatory protein YycI -
  NH16_RS03070 (NH16_03065) - 601365..602657 (-) 1293 WP_048592490.1 hypothetical protein -
  NH16_RS03075 (NH16_03070) walK 602647..604512 (-) 1866 WP_048593126.1 cell wall metabolism sensor histidine kinase WalK -
  NH16_RS03080 (NH16_03075) yycF 604580..605287 (-) 708 WP_010281559.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39162.39 Da        Isoelectric Point: 9.7092

>NTDB_id=150145 NH16_RS03060 WP_048592489.1 599305..600444(-) (htrA) [Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484]
MVQSALTKTLLTGVIAGVVGGGAILYGQQGVQLLQNQNQKVSTTATSTKTIAKNATATSAYNKVSDAVVSVLNFTKSSQG
SYQESSEGSGVIYKKTDGSAFIVTNNHVITGAAKIQVMLHSGKKVTATLVGKDAMTDLAVLKIDGTDVTTTAQFGDSSKI
TVGENVLAIGSPLGSEYASSVTQGIISAKKRLVEATSENGQNDGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
TSSSGTSVEGMGFAIPSDQVVDIVNKLVKDGKVTRPAIGISLINLSEVTASEQKSTLKIPDSVTGGVVVMSLTNNGPADK
AGLKKYDVIVGINGKKVSSQADLREELYKHSLGDTITLTYYHQDTKQTVKVKLTQKLAS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=150145 NH16_RS03060 WP_048592489.1 599305..600444(-) (htrA) [Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484]
ATGGTACAATCAGCATTAACAAAAACGTTGTTAACTGGCGTCATTGCTGGTGTTGTTGGTGGAGGAGCAATTTTGTATGG
GCAGCAGGGTGTACAATTGTTACAAAATCAAAATCAAAAAGTGAGTACGACAGCAACAAGTACAAAAACAATTGCCAAGA
ATGCAACTGCTACATCAGCTTATAATAAGGTATCAGATGCAGTTGTATCTGTATTGAACTTTACTAAATCCAGTCAAGGT
AGTTATCAAGAATCGTCAGAAGGTTCTGGCGTGATCTATAAAAAAACGGATGGATCGGCATTTATTGTAACGAATAATCA
CGTAATCACTGGAGCGGCTAAAATTCAAGTTATGCTGCACAGTGGGAAGAAAGTGACCGCTACATTAGTCGGCAAAGATG
CGATGACTGACTTAGCTGTTCTGAAAATCGACGGCACAGACGTTACAACAACTGCACAATTTGGCGATTCAAGTAAAATA
ACTGTTGGTGAAAACGTCTTGGCAATTGGTTCGCCGCTGGGATCTGAGTATGCTTCGTCAGTGACGCAAGGCATCATTTC
GGCCAAGAAAAGGTTAGTTGAGGCAACATCTGAAAATGGTCAAAATGATGGTGGATCCACGGTTATTCAGACGGATGCTG
CTATTAATCCTGGTAATTCAGGTGGACCATTAATCAACTTTGCAGGACAAGTTATTGGTATTAACTCAATGAAGTTGTCA
ACATCTTCTTCTGGAACGAGCGTTGAGGGGATGGGTTTTGCAATTCCTTCTGATCAAGTCGTTGACATTGTTAACAAATT
AGTCAAAGATGGTAAAGTCACACGACCAGCAATTGGCATTAGTTTGATTAATTTGTCAGAAGTAACAGCTTCTGAGCAAA
AATCAACATTGAAAATTCCAGATAGCGTTACTGGTGGTGTTGTTGTAATGAGTTTGACTAACAATGGCCCAGCAGATAAA
GCTGGATTGAAGAAGTACGACGTTATTGTTGGCATTAATGGTAAAAAGGTCAGCTCACAGGCTGATCTGCGAGAAGAACT
CTACAAGCATTCGCTTGGGGACACAATAACATTGACTTATTATCATCAGGATACTAAGCAAACCGTCAAGGTTAAATTAA
CACAGAAATTAGCAAGCTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

PDZ domain (PDZ_2)

(276-373)

Peptidase family M50 (Peptidase_M50)

(221-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

52.394

93.668

0.491
  htrA Streptococcus gordonii str. Challis substr. CH1

48.549

100

0.485
  htrA Streptococcus pneumoniae D39

52.924

90.237

0.478
  htrA Streptococcus pneumoniae TIGR4

52.924

90.237

0.478
  htrA Streptococcus pneumoniae R6

52.924

90.237

0.478
  htrA Streptococcus pneumoniae Rx1

52.924

90.237

0.478
  htrA Streptococcus mutans UA159

52.647

89.71

0.472

Multiple sequence alignment