Detailed information NTG0001469

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: ASU2_RS05085
• Genome accession: NC_018690
• Coordinates: 1115311..1116504 (-)
• Length: 397 a.a.
• NCBI ID: WP_014991733.1
• Uniprot ID: K0GBS3
• Organism: Actinobacillus suis H91-0380
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1110311..1121504

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASU2_RS05060 (ASU2_05010)	lptE	1112103..1112597 (+)	495	WP_005597385.1	LPS assembly lipoprotein LptE	-
ASU2_RS05065 (ASU2_05015)	holA	1112705..1113730 (+)	1026	WP_014991730.1	DNA polymerase III subunit delta	-
ASU2_RS05070 (ASU2_05020)	yacG	1113807..1113995 (-)	189	WP_005623139.1	DNA gyrase inhibitor YacG	-
ASU2_RS05075 (ASU2_05025)	coaE	1113977..1114615 (-)	639	WP_014991731.1	dephospho-CoA kinase	-
ASU2_RS05080 (ASU2_05030)	pilD	1114637..1115311 (-)	675	WP_014991732.1	fimbrial protein	Machinery gene
ASU2_RS05085 (ASU2_05035)	pilC	1115311..1116504 (-)	1194	WP_014991733.1	type II secretion system F family protein	Machinery gene
ASU2_RS05090 (ASU2_05040)	pilB	1116497..1117882 (-)	1386	WP_014991734.1	GspE/PulE family protein	Machinery gene
ASU2_RS05095 (ASU2_05045)	pilA	1117903..1118340 (-)	438	WP_014991735.1	pilin	Machinery gene
ASU2_RS05100 (ASU2_05050)	radA	1118520..1119899 (+)	1380	WP_014991736.1	DNA repair protein RadA	Machinery gene
ASU2_RS05105 (ASU2_05055)	pepB	1119965..1121248 (+)	1284	WP_014991737.1	aminopeptidase PepB	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 45035.68 Da
• Isoelectric Point: 9.6943

>NTDB_id=1469 ASU2_RS05085 WP_014991733.1 1115311..1116504(-) (pilC) [Actinobacillus suis H91-0380]
MVSIFEFHWKAKNRFQQKQSGILLAQNHAEAEQKLLAKGYQYIHIQRNFTFSRQPKADEVTQFLAQLALLINASIPFKQA
LMMQQENCTNIKLYQWLLALNASISSGYSFSASLAKLDLYLSKQEIQLIRMGEQSGKLSVVLENIAKTRNQADKLAKKVR
KITFYPLIVLVISCVLTLGLLVFIVPQFADLYMGKAQNLPWLTSLLFSLSAFLRQNGIFLCCGSIVVMGVLLCFAKKFGN
LTACQMRLLSYIPFFNQVIRYTRIIFFTQNLALMLSAHLHLEVALKAFLAEKMHDRLLQEQVRLTLSLLQQGYKFSEGLN
PAVFTPQMVQMITIGEKSANLAVMCTQISDIYQLKLDYQIDLLSQLLEPILMLLMGIIIGTVLIGLYLPIFDLGILV

Nucleotide

• Length: 1194 bp

>NTDB_id=1469 ASU2_RS05085 WP_014991733.1 1115311..1116504(-) (pilC) [Actinobacillus suis H91-0380]
ATGGTTAGTATTTTTGAATTTCACTGGAAAGCGAAGAATCGTTTTCAACAAAAACAAAGTGGTATTTTATTAGCCCAAAA
TCATGCTGAGGCAGAACAAAAGCTCTTGGCAAAAGGTTATCAATATATTCATATTCAACGCAATTTTACTTTTTCTCGAC
AGCCTAAAGCAGATGAAGTTACTCAATTTCTTGCGCAATTAGCATTATTGATTAATGCTTCCATTCCTTTTAAACAAGCG
TTAATGATGCAGCAGGAAAATTGTACGAATATTAAGTTATATCAATGGCTATTAGCTTTAAATGCTTCGATAAGCTCAGG
ATATAGCTTTTCTGCGAGTTTAGCGAAATTGGATCTTTATCTTTCTAAGCAAGAAATCCAATTAATTCGGATGGGCGAAC
AAAGTGGTAAATTAAGTGTGGTTTTGGAAAATATTGCTAAAACACGTAATCAAGCAGATAAATTAGCGAAGAAAGTCAGA
AAAATTACATTTTATCCGCTGATTGTATTAGTCATTTCGTGTGTATTGACGCTTGGGTTGTTAGTTTTTATTGTGCCTCA
ATTTGCCGATTTGTATATGGGTAAGGCACAGAATTTGCCATGGTTAACGTCATTATTATTTTCTCTCTCTGCGTTTTTAC
GACAGAATGGGATATTTCTATGTTGTGGCAGTATAGTAGTGATGGGAGTGTTGCTCTGTTTTGCAAAAAAATTCGGAAAT
TTGACCGCTTGTCAGATGCGTCTGTTGTCTTATATCCCCTTCTTTAATCAAGTTATTCGTTATACGAGAATTATCTTCTT
TACTCAGAATCTTGCGCTAATGTTAAGTGCCCATCTGCATTTAGAAGTGGCTCTAAAAGCTTTTTTAGCTGAGAAAATGC
ACGATAGACTTTTACAGGAACAAGTACGACTTACGTTATCTTTATTACAACAAGGGTATAAATTTTCGGAAGGATTAAAC
CCGGCAGTATTCACTCCACAAATGGTACAAATGATCACGATAGGAGAGAAAAGTGCTAATTTAGCGGTGATGTGTACGCA
GATTAGTGATATTTATCAGCTGAAATTAGATTATCAAATAGATTTGCTTTCACAATTACTTGAGCCGATTTTAATGCTAC
TTATGGGGATTATTATTGGCACGGTTTTAATTGGGCTTTATTTGCCGATTTTTGATTTGGGGATTCTCGTATAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

3D structure

• AlphaFold DB: K0GBS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	47.859	100	0.479
pilC	Haemophilus influenzae Rd KW20	39.75	100	0.401
pilC	Haemophilus influenzae 86-028NP	39.5	100	0.398