Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ASU2_RS06170 Genome accession   NC_018690
Coordinates   1349840..1351135 (-) Length   431 a.a.
NCBI ID   WP_014991934.1    Uniprot ID   A0ABT1WV77
Organism   Actinobacillus suis H91-0380     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1344840..1356135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ASU2_RS06140 (ASU2_06085) suhB 1345012..1345824 (-) 813 WP_014991928.1 inositol-1-monophosphatase -
  ASU2_RS06145 (ASU2_06090) - 1345991..1347088 (+) 1098 WP_014991929.1 TrmH family RNA methyltransferase -
  ASU2_RS06150 (ASU2_06095) - 1347150..1347776 (-) 627 WP_014991930.1 LysE family transporter -
  ASU2_RS06155 (ASU2_06100) - 1347785..1348258 (-) 474 WP_014991931.1 phosphatidylglycerophosphatase A family protein -
  ASU2_RS06160 (ASU2_06105) thiL 1348271..1349236 (-) 966 WP_014991932.1 thiamine-phosphate kinase -
  ASU2_RS06165 (ASU2_06110) nusB 1349301..1349714 (-) 414 WP_014991933.1 transcription antitermination factor NusB -
  ASU2_RS06170 (ASU2_06115) comE 1349840..1351135 (-) 1296 WP_014991934.1 type IV pilus secretin PilQ Machinery gene
  ASU2_RS06175 (ASU2_06120) comD 1351145..1351549 (-) 405 WP_014991935.1 hypothetical protein Machinery gene
  ASU2_RS06180 (ASU2_06125) comC 1351542..1352069 (-) 528 WP_014991936.1 hypothetical protein Machinery gene
  ASU2_RS06185 (ASU2_06130) comB 1352072..1352593 (-) 522 WP_014991937.1 hypothetical protein Machinery gene
  ASU2_RS06190 (ASU2_06135) comA 1352575..1353261 (-) 687 WP_014991938.1 hypothetical protein Machinery gene
  ASU2_RS06195 (ASU2_06140) - 1353400..1355985 (+) 2586 WP_014991939.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 47947.13 Da        Isoelectric Point: 9.4585

>NTDB_id=1465 ASU2_RS06170 WP_014991934.1 1349840..1351135(-) (comE) [Actinobacillus suis H91-0380]
MKRMILLLFFILPPVIAHAFSISLKNAPTAKILSYLAEEHGKNIVLSDNIETNTTLRIENSNFDSVLKSITRANKLTSAY
ENQIYFIGHKKDDKDPNRGLNLELLKPKLITKTIKLDYAKAAEVIESLTKGSGNFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIRNLDRPTEQIAIEARIVTISSENLQELGVRWGMFSPANGHHKIAGSLEANGLPNTNHLNVNFPVNNAASLALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDNQ
ILLDLVVTQNSPNSTSSTVHGLVTIDKQELNTQVFAQHGETIVLGGIFQHLTAKGEDRVPILGSIPVLKKLFSHSSDRIS
KRELVIFVTPYIIKSEKQQISSHSLQKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=1465 ASU2_RS06170 WP_014991934.1 1349840..1351135(-) (comE) [Actinobacillus suis H91-0380]
ATGAAAAGAATGATTTTGCTACTCTTTTTTATATTGCCCCCTGTGATTGCACATGCGTTTTCTATTTCATTAAAAAATGC
GCCGACCGCAAAAATTCTGAGTTATTTAGCGGAAGAGCACGGAAAAAATATTGTGCTAAGCGACAATATTGAAACGAATA
CCACATTAAGAATTGAAAATAGCAATTTTGATAGTGTGTTAAAAAGTATTACTCGAGCAAATAAGTTGACCAGTGCGTAT
GAAAACCAAATCTATTTTATTGGTCATAAAAAAGACGATAAGGATCCTAACAGGGGATTAAATCTGGAATTATTAAAACC
TAAACTGATTACTAAAACCATTAAGTTAGATTATGCTAAAGCAGCGGAAGTAATTGAATCTTTAACTAAAGGTAGCGGTA
ATTTTTTATCGGAAAACGGCTATTTACATTTTGATGATCGCAGTAATAGTTTGATTATTAAAGATAGCCCGGAATCAATG
AAAAATATCGTGAAATTAATCAGAAATTTGGATAGACCGACCGAACAGATTGCAATTGAAGCGAGAATAGTCACAATCAG
TAGTGAGAATTTACAAGAGCTTGGCGTGCGTTGGGGAATGTTTTCTCCTGCAAACGGACATCATAAAATTGCCGGTTCGC
TTGAAGCAAATGGGCTACCGAATACTAATCATTTAAACGTCAATTTTCCGGTAAATAATGCTGCTTCACTTGCGCTACAA
GTGGCAAAAATTAATGGGCGAGTGCTTGATTTGGAACTTACCGCTTTGGAACAAGAAAATGATGTAGAAATTATTGCCAG
CCCACGTTTACTGACCACTAATAAGAAACCGGCAAGTATCAAACAAGGGACTGAAATTCCTTATGTGCTTTATAACCGTA
AAGATGAAGTGAAAAATATCGAATTTAAAGAAGCCGTTTTAGGGCTACAGGTTACACCGCATATTTCAAACGATAATCAA
ATTTTGCTTGATCTGGTGGTGACACAAAATTCACCAAATTCAACCAGTTCAACGGTACACGGTTTAGTGACGATTGATAA
GCAGGAACTGAATACTCAGGTATTTGCTCAACACGGTGAGACTATTGTACTTGGTGGTATTTTTCAGCATTTAACTGCAA
AAGGTGAGGATAGAGTCCCAATTTTAGGTTCAATTCCAGTACTTAAAAAATTATTTAGCCATTCCAGTGATAGGATCAGT
AAGCGTGAATTAGTTATTTTCGTTACACCTTATATTATCAAAAGCGAAAAACAGCAAATTTCCTCGCATTCTCTACAGAA
ATTACCGCCAAAATAA

Domains

Predicted by InterProScan.

Bacterial type II and III secretion system protein (Secretin)

(255-414)

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

66.587

96.52

0.643
  comE Haemophilus influenzae Rd KW20

52.817

98.84

0.522
  comE Haemophilus influenzae 86-028NP

52.582

98.84

0.52
  pilQ Vibrio campbellii strain DS40M4

42.08

98.144

0.413
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.754

96.056

0.411
  pilQ Vibrio cholerae strain A1552

42.754

96.056

0.411

Multiple sequence alignment