Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   AA977_RS00205 Genome accession   NZ_CP011486
Coordinates   37688..38431 (+) Length   247 a.a.
NCBI ID   WP_064434118.1    Uniprot ID   -
Organism   Helicobacter pylori strain K26A1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32688..43431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA977_RS00180 (AA977_00185) panD 34843..35193 (+) 351 WP_064434116.1 aspartate 1-decarboxylase -
  AA977_RS00185 (AA977_00190) - 35204..35497 (+) 294 WP_000347932.1 YbaB/EbfC family nucleoid-associated protein -
  AA977_RS00190 (AA977_00195) - 35497..36492 (+) 996 WP_064434117.1 PDZ domain-containing protein -
  AA977_RS00195 (AA977_00200) comB6 36498..37562 (+) 1065 WP_064435164.1 P-type conjugative transfer protein TrbL Machinery gene
  AA977_RS00200 (AA977_00205) comB7 37578..37691 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  AA977_RS00205 (AA977_00210) comB8 37688..38431 (+) 744 WP_064434118.1 virB8 family protein Machinery gene
  AA977_RS00210 (AA977_00215) comB9 38431..39408 (+) 978 WP_064434119.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  AA977_RS00215 (AA977_00220) comB10 39401..40543 (+) 1143 WP_064434120.1 DNA type IV secretion system protein ComB10 Machinery gene
  AA977_RS00220 (AA977_00225) - 40609..42021 (+) 1413 WP_064434121.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  AA977_RS00225 (AA977_00230) gmd 42040..43185 (+) 1146 WP_064434122.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28761.06 Da        Isoelectric Point: 9.2903

>NTDB_id=146274 AA977_RS00205 WP_064434118.1 37688..38431(+) (comB8) [Helicobacter pylori strain K26A1]
MKEKPFNSEQLVFLEELLSQQEKHLENKLSSFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIVFVLAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSNAKVWQRFEDVIKTNNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENRLVYEKRYKIVMSYVFDAPDFDYASMPKNPTGFKVIRYSITEI
APRNKSD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=146274 AA977_RS00205 WP_064434118.1 37688..38431(+) (comB8) [Helicobacter pylori strain K26A1]
ATGAAAGAAAAGCCTTTCAACAGCGAGCAGTTAGTCTTTTTAGAAGAGCTTTTAAGCCAGCAAGAAAAGCATTTAGAAAA
CAAGCTCTCTAGTTTTTCAGTGAGTGATTTGGACATGCAAAGCGTGTTTAGGCTGGAGAGGAATCGTTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGTTTTTGTTTTAGCGATCGTGTTAATCAGCCTCCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAAGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCTTTAGCCCGATCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAGTCGCGCT
ATGAACTGGTGCGCTTGCAAAGCAATGCTAAAGTGTGGCAGCGTTTTGAAGATGTGATTAAAACCAATAACAGCATTTAC
GCGCAAAGCCATTTGGAAAGAGAGGTTCATATCGTCAATATTGCGATTTATCAGCAAGATAATAACCCCATTGCAAGCGT
GTCCATTGCCGCCAAACTCTTGAATGAAAACAGATTAGTGTATGAAAAGCGTTATAAAATCGTGATGAGTTATGTTTTTG
ACGCTCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAGGTTATCCGCTATAGCATCACTGAAATT
GCACCCAGAAACAAGAGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

91.093

100

0.911

Multiple sequence alignment