NTDB

Overview

Name	comE/blpR	Type	Regulator
Locus tag	AWB63_RS08875	Genome accession	NZ_CP014144
Coordinates	1941242..1941985 (-)	Length	247 a.a.
NCBI ID	WP_002885796.1	Uniprot ID	-
Organism	Streptococcus salivarius strain JF
Function	activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1936242..1946985

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AWB63_RS08860 (AWB63_08860)	rnpA	1936965..1937300 (-)	336	WP_002891957.1	ribonuclease P protein component	-
AWB63_RS08865 (AWB63_08865)	argH	1937385..1938770 (-)	1386	WP_048790873.1	argininosuccinate lyase	-
AWB63_RS08870 (AWB63_08870)	-	1939097..1940296 (-)	1200	WP_002885646.1	argininosuccinate synthase	-
AWB63_RS08875 (AWB63_08875)	comE/blpR	1941242..1941985 (-)	744	WP_002885796.1	response regulator transcription factor	Regulator
AWB63_RS08880 (AWB63_08880)	-	1941987..1943303 (-)	1317	WP_038676818.1	GHKL domain-containing protein	-
AWB63_RS08885 (AWB63_08885)	-	1943327..1944607 (-)	1281	WP_038676820.1	hypothetical protein	-
AWB63_RS08890 (AWB63_08890)	-	1944629..1945519 (-)	891	WP_038676823.1	hypothetical protein	-
AWB63_RS08895 (AWB63_08895)	-	1945579..1946886 (-)	1308	WP_038676824.1	GHKL domain-containing protein	-

Sequence

Protein

Download Length: 247 a.a. Molecular weight: 28536.83 Da Isoelectric Point: 6.7589

                                >NTDB_id=144453 AWB63_RS08875 WP_002885796.1 1941242..1941985(-) (comE/blpR) [Streptococcus salivarius strain JF]

MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD

ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY

FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK

WSEVKEH

Nucleotide

Download Length: 744 bp

                                >NTDB_id=144453 AWB63_RS08875 WP_002885796.1 1941242..1941985(-) (comE/blpR) [Streptococcus salivarius strain JF]

ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGCATTAGCGACATCATCCGAGAATTGGTTTCAGAGGG

CACGTTTTCTGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAACGAGAAGGGCAACCATC

AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT

GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATCAGTTTTAAATACAAGGTTTCTGCACTAGA

TTTCATTGATAAGACAGTTTCTAATGCAGAATTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG

GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT

TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTAATTACCAAAACAGAGCGTCTGGAGTTTTATGCCAATCTTGGAGA

TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA

AGACTCAGTTGATGATTTACTTTGAAAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCCTGCTTAAAAAA

TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE/blpR	Streptococcus mutans UA159	47.5	97.166	0.462
comE/comE2	Streptococcus equinus JB1	42.857	99.19	0.425
comE/comE1	Streptococcus equinus JB1	40.496	97.976	0.397
comE/comE2	Streptococcus gordonii strain NCTC7865	37.402	100	0.385
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.402	100	0.385

Detailed information NTG0144453