Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   AU077_RS00695 Genome accession   NZ_CP013688
Coordinates   136073..136804 (+) Length   243 a.a.
NCBI ID   WP_058621372.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 131073..141804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS10505 - 131476..133046 (+) 1571 WP_099412448.1 IS3 family transposase -
  AU077_RS00675 (AU077_00675) - 133642..133842 (+) 201 WP_058621369.1 hypothetical protein -
  AU077_RS00690 (AU077_00690) - 135730..136056 (+) 327 WP_058621371.1 LytTR family DNA-binding domain-containing protein -
  AU077_RS00695 (AU077_00695) comE/comE1 136073..136804 (+) 732 WP_058621372.1 response regulator transcription factor Regulator
  AU077_RS00700 (AU077_00700) comD/comD1 136809..138119 (+) 1311 WP_058621373.1 sensor histidine kinase Regulator
  AU077_RS11135 comC/comC1 138137..138277 (-) 141 WP_014295304.1 hypothetical protein Regulator
  AU077_RS00705 (AU077_00705) - 138578..138877 (+) 300 WP_058621374.1 DUF3884 family protein -
  AU077_RS00710 (AU077_00710) - 138887..139036 (+) 150 WP_039671232.1 hypothetical protein -
  AU077_RS00715 (AU077_00715) - 139048..139359 (+) 312 WP_039671231.1 bacteriocin immunity protein -
  AU077_RS11140 (AU077_00720) - 139631..139801 (+) 171 WP_058621375.1 hypothetical protein -
  AU077_RS00725 (AU077_00725) comD/comD3 139933..140247 (+) 315 WP_058621376.1 GHKL domain-containing protein Regulator
  AU077_RS00730 (AU077_00730) - 140377..140634 (+) 258 WP_014295297.1 hypothetical protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28480.66 Da        Isoelectric Point: 5.4370

>NTDB_id=141906 AU077_RS00695 WP_058621372.1 136073..136804(+) (comE/comE1) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEMFCSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREK
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRVLYSDIL
YFETSPAVHRVILHTKNERVEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDRATRSVYFETGDTCLVSRDKIKPLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=141906 AU077_RS00695 WP_058621372.1 136073..136804(+) (comE/comE1) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGATGTTTTGTTCCGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCTATTCGTGAAAAA
GATGCAACAGCTATCATTGTTTTTGTAACAACTCATTCAGAATTTATGCTGCTGACCTACCAAGCGTTAGTAGGGGCAAT
TGATTTTATTGATAAAAACCTAAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCCATGAAACATC
AAAATGATAATTTCGGCGAAAACTCCTTTTTGTTTGAAACTCCTAAAGCACGTGTGCGCGTTCTATATAGTGATATTCTT
TATTTCGAAACATCTCCTGCCGTGCACCGCGTGATTTTGCATACGAAAAATGAAAGAGTGGAATTTTATGCGACGATTGC
AGAGATTGCTAAATCAGACAAACGTCTTTTCAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTTAGATTTG
ATAGAGCGACACGAAGTGTTTATTTCGAAACTGGAGACACTTGCCTAGTTTCGAGGGATAAAATAAAACCTCTATTAAAT
GAGATGAGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-123)

LytTr DNA-binding domain (LytTR)

(152-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

72.016

100

0.72
  comE/blpR Streptococcus mutans UA159

48.954

98.354

0.481
  comE/comE2 Streptococcus equinus JB1

46.281

99.588

0.461

Multiple sequence alignment