Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   APQ13_RS07445 Genome accession   NZ_CP013237
Coordinates   1559222..1559803 (-) Length   193 a.a.
NCBI ID   WP_002263134.1    Uniprot ID   Q8DWL7
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1554222..1564803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS07435 (APQ13_07420) - 1554657..1558382 (-) 3726 WP_002267555.1 phosphoribosylformylglycinamidine synthase -
  APQ13_RS07440 (APQ13_07425) purC 1558392..1559099 (-) 708 WP_002263133.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  APQ13_RS07445 (APQ13_07430) comA 1559222..1559803 (-) 582 WP_002263134.1 ATP-binding cassette domain-containing protein Regulator
  APQ13_RS07450 (APQ13_07435) - 1560031..1560279 (-) 249 WP_002263135.1 acyl carrier protein -
  APQ13_RS07455 (APQ13_07440) plsX 1560281..1561279 (-) 999 WP_002263136.1 phosphate acyltransferase PlsX -
  APQ13_RS07460 (APQ13_07445) recO 1561487..1562242 (-) 756 WP_002263137.1 DNA repair protein RecO Machinery gene
  APQ13_RS07465 (APQ13_07450) - 1562232..1563407 (-) 1176 WP_002273747.1 pyridoxal phosphate-dependent aminotransferase -
  APQ13_RS07470 (APQ13_07455) - 1563496..1564464 (-) 969 WP_002263139.1 ribose-phosphate diphosphokinase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21388.42 Da        Isoelectric Point: 4.8930

>NTDB_id=139705 APQ13_RS07445 WP_002263134.1 1559222..1559803(-) (comA) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MGKSGSGKTTLAKILAGYYTVSSGDSFLDGEKINYSQLRQLVTYVPQQSYVFTGTILDNLLLGAEEEVTDDRLMEVCSIA
EILDNIKAMPLGFQTQISEDGGLSGGQKQRLAIARALLTRQPVLIFDEATSGLDRDTEEKVIANLSKLERTIIFIAHRGS
VSYYADRIVEIDSGEKIKDRINHRPFSFLMMTL

Nucleotide


Download         Length: 582 bp        

>NTDB_id=139705 APQ13_RS07445 WP_002263134.1 1559222..1559803(-) (comA) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGGGGAAAAGTGGTTCTGGAAAGACAACTTTGGCAAAAATTCTTGCAGGCTATTATACTGTTAGTAGCGGTGACTCTTT
CTTAGATGGAGAAAAGATAAATTATTCCCAGCTGCGCCAATTAGTAACTTATGTGCCACAGCAGTCTTATGTTTTTACAG
GAACAATCTTAGATAATCTGCTTCTTGGTGCTGAAGAGGAAGTAACGGATGATCGCTTAATGGAAGTTTGTTCAATTGCT
GAAATTTTAGACAATATCAAGGCAATGCCTTTAGGTTTTCAAACACAGATTTCAGAAGACGGCGGTTTATCTGGTGGTCA
AAAACAGCGTTTAGCTATTGCACGTGCTCTCTTAACCAGACAGCCTGTGTTGATTTTTGATGAGGCAACTAGTGGTTTAG
ATCGTGATACCGAAGAAAAAGTTATTGCCAATTTATCTAAATTGGAGCGCACGATTATTTTTATTGCTCACCGAGGCAGT
GTTTCTTATTATGCTGATCGAATTGTTGAGATTGACTCTGGAGAGAAAATTAAGGATAGAATAAATCATCGTCCTTTCTC
ATTTTTGATGATGACTCTTTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DWL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

50.802

96.891

0.492
  comA Streptococcus gordonii str. Challis substr. CH1

51.099

94.301

0.482
  comA/nlmT Streptococcus mutans UA159

49.468

97.409

0.482
  comA Streptococcus pneumoniae D39

49.18

94.819

0.466
  comA Streptococcus pneumoniae Rx1

49.18

94.819

0.466
  comA Streptococcus pneumoniae R6

49.18

94.819

0.466
  comA Streptococcus mitis SK321

48.087

94.819

0.456
  comA Streptococcus pneumoniae TIGR4

48.087

94.819

0.456

Multiple sequence alignment