Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   HSISS4_RS08810 Genome accession   NZ_CP013216
Coordinates   1923180..1923923 (-) Length   247 a.a.
NCBI ID   WP_002885796.1    Uniprot ID   -
Organism   Streptococcus salivarius strain HSISS4     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1918180..1928923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS08795 (HSISS4_01712) rnpA 1918904..1919239 (-) 336 WP_002891957.1 ribonuclease P protein component -
  HSISS4_RS08800 (HSISS4_01713) argH 1919324..1920709 (-) 1386 WP_037601513.1 argininosuccinate lyase -
  HSISS4_RS08805 (HSISS4_01714) - 1921036..1922235 (-) 1200 WP_002885646.1 argininosuccinate synthase -
  HSISS4_RS08810 (HSISS4_01715) comE/blpR 1923180..1923923 (-) 744 WP_002885796.1 response regulator transcription factor Regulator
  HSISS4_RS08815 (HSISS4_01716) - 1923925..1925241 (-) 1317 WP_021144662.1 GHKL domain-containing protein -
  HSISS4_RS08820 (HSISS4_01717) - 1925265..1926545 (-) 1281 WP_021144663.1 hypothetical protein -
  HSISS4_RS08825 (HSISS4_01718) - 1926567..1927457 (-) 891 WP_002885882.1 hypothetical protein -
  HSISS4_RS08830 (HSISS4_01719) - 1927517..1928824 (-) 1308 WP_002885760.1 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28536.83 Da        Isoelectric Point: 6.7589

>NTDB_id=139528 HSISS4_RS08810 WP_002885796.1 1923180..1923923(-) (comE/blpR) [Streptococcus salivarius strain HSISS4]
MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY
FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVKEH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=139528 HSISS4_RS08810 WP_002885796.1 1923180..1923923(-) (comE/blpR) [Streptococcus salivarius strain HSISS4]
ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCAGAGAATTGGTTTCAGAGGG
CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAATGAAAAGGGCAACCATC
AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTTGCCTCAGAAATTCGTCAACAAGAT
GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATTAGTTTTAAATACAAGGTTTCTGCACTAGA
TTTCATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG
GAGATGTGGATGATGATGAGATTTTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT
TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTGATTACTAAAACAGAGCGTTTGGAGTTTTATGCCAATCTTGGAGA
TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA
AGACTCAGTTGATGATTTATTTTGAAAATGGTGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCTCTGCTTAAAAAA
TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.5

97.166

0.462
  comE/comE2 Streptococcus equinus JB1

42.857

99.19

0.425
  comE/comE1 Streptococcus equinus JB1

40.496

97.976

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.402

100

0.385
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.402

100

0.385

Multiple sequence alignment