Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   RN86_RS03050 Genome accession   NZ_CP012648
Coordinates   650185..651546 (+) Length   453 a.a.
NCBI ID   WP_052721528.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 645185..656546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS03020 (RN86_03015) dnaA 645470..646822 (-) 1353 WP_053794273.1 chromosomal replication initiator protein DnaA -
  RN86_RS03025 (RN86_03020) spo0J 647026..647790 (-) 765 WP_045504981.1 ParB/RepB/Spo0J family partition protein Regulator
  RN86_RS03030 (RN86_03025) htrA 647856..649049 (-) 1194 WP_045504979.1 S1C family serine protease Regulator
  RN86_RS03035 (RN86_03030) rlmH 649243..649722 (+) 480 WP_008808034.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RN86_RS11220 comC/comC1 650008..650172 (+) 165 WP_080998577.1 bacteriocin Regulator
  RN86_RS03050 (RN86_03045) comD/comD2 650185..651546 (+) 1362 WP_052721528.1 competence system sensor histidine kinase ComD Regulator
  RN86_RS03055 (RN86_03050) comE/comE2 651543..652310 (+) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  RN86_RS03070 (RN86_03065) ychF 652632..653747 (+) 1116 WP_008808030.1 redox-regulated ATPase YchF -
  RN86_RS03075 (RN86_03070) pth 653821..654390 (+) 570 WP_046164770.1 aminoacyl-tRNA hydrolase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 52772.26 Da        Isoelectric Point: 5.7034

>NTDB_id=135437 RN86_RS03050 WP_052721528.1 650185..651546(+) (comD/comD2) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MMNFEKIFAIFSLLVQTISFVTVYKKICDIKKLNISIIFLYLTISFSSLILAQFYNLLPEYGDVLSTFLHYLLIFFQPLI
LHLYFSKKGLYKGYVSIFLSLLIYLSVSSSETFFSVIISSVTGDDFVNQYWGSYYTIVNILALFFVLKSFEFFEFEFSYF
KNFDFEKEIMNVIKIYVTIHILLNISHWFSENAHLNSFASMIATIGFIMFLSTLFYLKSAREQHEKAKEIQQKKEEQRQL
QLYTDEIVGLYNEIRGFRHDYAGMLTSLQTGINSGDMKEVERIFHNVLSQANISLRSDDYTFFELNNVQDTALRSVLIQT
IFKARECGVEIVFEMKDVIETLPMKLLDLVRVASVLLNNAVEGAAESPSKTMNVSLVKLDKEIVFVIQNSRQSRYINLEE
IYEVGFSTKGENRGLGLNNVKEIIDKYDEVILETDIETNYFIQVVRFKRKEKI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=135437 RN86_RS03050 WP_052721528.1 650185..651546(+) (comD/comD2) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGATGAATTTTGAAAAAATATTTGCTATTTTCTCTTTACTAGTTCAAACAATTTCTTTTGTTACTGTATACAAAAAAAT
ATGTGATATAAAAAAATTAAATATTTCTATCATATTTCTGTACTTAACAATAAGTTTTAGTAGTTTGATATTAGCACAGT
TTTATAATTTATTACCCGAATATGGAGATGTATTAAGTACTTTCTTACATTACTTACTTATATTTTTCCAACCACTAATC
TTACATTTATATTTTTCTAAAAAAGGATTATATAAAGGATATGTATCTATCTTTTTATCCCTACTTATATATCTTTCTGT
ATCATCTTCTGAAACTTTTTTCTCAGTTATTATATCTTCAGTGACAGGAGATGATTTTGTTAATCAATACTGGGGTTCTT
ACTATACTATAGTAAATATCTTAGCATTATTTTTTGTTTTGAAATCTTTTGAATTTTTTGAGTTTGAATTTAGTTATTTT
AAAAATTTTGATTTTGAAAAAGAAATAATGAATGTAATTAAAATTTATGTAACGATTCATATCCTATTAAATATTTCTCA
TTGGTTTAGCGAAAACGCACATCTTAATAGTTTTGCTAGTATGATTGCCACTATAGGATTTATTATGTTTTTGTCGACTT
TATTTTATCTAAAGTCTGCTCGTGAACAACATGAAAAAGCAAAAGAAATTCAGCAAAAAAAGGAAGAACAAAGACAACTA
CAACTTTATACAGATGAAATTGTAGGTCTTTATAACGAAATTCGAGGTTTTCGTCACGATTATGCTGGTATGTTAACAAG
TTTGCAAACCGGAATTAACTCAGGTGATATGAAAGAAGTAGAGCGAATCTTTCATAATGTTTTAAGTCAAGCTAATATTT
CCCTTCGATCAGATGACTATACTTTTTTTGAGTTAAATAATGTTCAAGACACTGCCTTGAGAAGTGTGTTAATTCAAACT
ATATTTAAGGCTCGAGAGTGTGGAGTAGAGATCGTATTTGAAATGAAGGATGTTATTGAGACATTACCTATGAAACTTTT
AGATTTAGTTCGAGTAGCTAGTGTATTGCTCAATAATGCGGTTGAAGGGGCAGCTGAAAGTCCCTCAAAAACAATGAACG
TGTCTTTAGTAAAGCTAGATAAAGAAATTGTTTTTGTAATTCAGAATTCTCGTCAAAGCCGTTACATTAATTTAGAAGAA
ATTTATGAAGTAGGCTTCTCGACAAAAGGAGAAAATCGAGGATTAGGTTTAAATAATGTCAAAGAAATTATTGACAAATA
TGATGAAGTTATTCTGGAAACAGATATAGAAACAAATTATTTTATACAAGTTGTAAGATTTAAAAGAAAGGAAAAAATAT
GA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(344-445)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

78.076

98.675

0.77
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

76.821

100

0.768
  comD/comD2 Streptococcus pneumoniae TIGR4

49.34

83.664

0.413
  comD/comD1 Streptococcus pneumoniae Rx1

49.077

83.664

0.411
  comD/comD1 Streptococcus pneumoniae D39

49.077

83.664

0.411
  comD/comD1 Streptococcus pneumoniae R6

49.077

83.664

0.411
  comD Streptococcus mitis NCTC 12261

48.285

83.664

0.404
  comD Streptococcus mitis SK321

48.404

83.002

0.402