Detailed information NTG0134815

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: AMD33_RS07000
• Genome accession: NZ_CP012588
• Coordinates: 1349255..1351408 (-)
• Length: 717 a.a.
• NCBI ID: WP_014727675.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MN-BM-A01
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1344255..1356408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AMD33_RS06965 (AMD33_06950)	-	1344375..1344605 (-)	231	WP_014608662.1	bacteriocin class II family protein	-
AMD33_RS06970 (AMD33_06955)	-	1344961..1345161 (-)	201	WP_011681569.1	hypothetical protein	-
AMD33_RS06975 (AMD33_06960)	-	1345180..1345356 (-)	177	WP_011681570.1	Blp family class II bacteriocin	-
AMD33_RS06980 (AMD33_06965)	-	1345607..1346344 (+)	738	WP_011681571.1	LytR/AlgR family response regulator transcription factor	-
AMD33_RS11860	-	1346875..1347678 (+)	804	WP_224102945.1	ATP-binding protein	-
AMD33_RS06990 (AMD33_06975)	-	1347696..1347857 (-)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
AMD33_RS06995 (AMD33_06980)	comB	1347872..1349239 (-)	1368	WP_011681574.1	bacteriocin secretion accessory protein	Regulator
AMD33_RS07000 (AMD33_06985)	comA/nlmT	1349255..1351408 (-)	2154	WP_014727675.1	peptide cleavage/export ABC transporter	Regulator
AMD33_RS07005 (AMD33_06990)	-	1352488..1354233 (-)	1746	WP_014727676.1	ABC transporter ATP-binding protein	-
AMD33_RS07010 (AMD33_06995)	-	1354226..1355863 (-)	1638	WP_014727677.1	ABC transporter ATP-binding protein	-
AMD33_RS11865 (AMD33_07000)	-	1356172..1356378 (-)	207	WP_002948879.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80653.45 Da
• Isoelectric Point: 6.9295

>NTDB_id=134815 AMD33_RS07000 WP_014727675.1 1349255..1351408(-) (comA/nlmT) [Streptococcus thermophilus strain MN-BM-A01]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSHRFTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=134815 AMD33_RS07000 WP_014727675.1 1349255..1351408(-) (comA/nlmT) [Streptococcus thermophilus strain MN-BM-A01]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTG
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCATCGATTTACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCCATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCACGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.787	99.582	0.675
comA	Streptococcus mitis NCTC 12261	65.963	99.163	0.654
comA	Streptococcus pneumoniae Rx1	65.541	99.163	0.65
comA	Streptococcus pneumoniae D39	65.541	99.163	0.65
comA	Streptococcus pneumoniae R6	65.541	99.163	0.65
comA	Streptococcus mitis SK321	65.26	99.163	0.647
comA	Streptococcus pneumoniae TIGR4	65.12	99.163	0.646
comA	Streptococcus gordonii str. Challis substr. CH1	63.866	99.582	0.636