Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SSAL8618_RS09525 Genome accession   NZ_CP009913
Coordinates   2051039..2052139 (-) Length   366 a.a.
NCBI ID   WP_126405090.1    Uniprot ID   A0AB37CLB3
Organism   Streptococcus salivarius strain NCTC 8618     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2046039..2057139
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL8618_RS09485 (SSAL8618_09485) - 2046647..2046844 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  SSAL8618_RS09490 (SSAL8618_09490) - 2047096..2048289 (-) 1194 WP_002885831.1 acetate kinase -
  SSAL8618_RS09495 (SSAL8618_09495) comYH 2048346..2049302 (-) 957 WP_038676858.1 class I SAM-dependent methyltransferase Machinery gene
  SSAL8618_RS09500 (SSAL8618_09500) comGG 2049347..2049664 (-) 318 WP_002887013.1 competence type IV pilus minor pilin ComGG -
  SSAL8618_RS09505 (SSAL8618_09505) comYF 2049642..2050079 (-) 438 WP_002887014.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSAL8618_RS09510 (SSAL8618_09510) comGE 2050066..2050296 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  SSAL8618_RS09515 (SSAL8618_09515) comYD 2050328..2050756 (-) 429 WP_254593949.1 competence type IV pilus minor pilin ComGD Machinery gene
  SSAL8618_RS09520 (SSAL8618_09520) comYC 2050716..2051030 (-) 315 WP_170314557.1 competence type IV pilus major pilin ComGC Machinery gene
  SSAL8618_RS09525 (SSAL8618_09525) comYB 2051039..2052139 (-) 1101 WP_126405090.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSAL8618_RS09530 (SSAL8618_09530) comGA/cglA/cilD 2052021..2052962 (-) 942 WP_038676863.1 competence type IV pilus ATPase ComGA Machinery gene
  SSAL8618_RS09535 (SSAL8618_09535) - 2053042..2053404 (-) 363 WP_002887019.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41608.71 Da        Isoelectric Point: 10.1478

>NTDB_id=132934 SSAL8618_RS09525 WP_126405090.1 2051039..2052139(-) (comYB) [Streptococcus salivarius strain NCTC 8618]
MPVKISKAIRQSAGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KTSLMRGDRLDQMFAAVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFATLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGADLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=132934 SSAL8618_RS09525 WP_126405090.1 2051039..2052139(-) (comYB) [Streptococcus salivarius strain NCTC 8618]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAATCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTTTAA
AGGCAGGGTTTACCTTGACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTAAAAGAATCGTCCTTGTCTCTTATG
AAAACGAGTTTAATGCGAGGCGATAGGTTGGACCAGATGTTTGCGGCAGTGGGCTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAACCTTCTAGGGAGTTTAACCAAGATTGAAACCTATATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATTCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGCGACTTTGTGCGGACTTCTTGTATTAAGCTTAATTCTCTACCTATGGGTCAAACGCCAGCCAGCTCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGGCAAACTGTCAGGCTATATACGACTGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTAGTTGCTCTAATGAAAGAGCAAAAGTCCAAGCTTTTTCGTGAGCT
GGGGGCTGATTTAGAAGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.81

93.716

0.514
  comYB Streptococcus mutans UA159

54.81

93.716

0.514
  comYB Streptococcus gordonii str. Challis substr. CH1

51.312

93.716

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

49.558

92.623

0.459
  comGB/cglB Streptococcus mitis SK321

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae Rx1

48.817

92.35

0.451
  comGB/cglB Streptococcus pneumoniae D39

48.817

92.35

0.451
  comGB/cglB Streptococcus pneumoniae R6

48.817

92.35

0.451
  comGB/cglB Streptococcus pneumoniae TIGR4

48.817

92.35

0.451
  comGB Lactococcus lactis subsp. cremoris KW2

44.377

89.891

0.399

Multiple sequence alignment