Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LG36_RS08060 Genome accession   NZ_CP009472
Coordinates   1687291..1687983 (-) Length   230 a.a.
NCBI ID   WP_038601521.1    Uniprot ID   -
Organism   Lactococcus lactis strain AI06     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1682291..1692983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LG36_RS08045 (LG36_1540) - 1683910..1684251 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  LG36_RS08050 (LG36_1541) - 1684383..1685624 (-) 1242 WP_038601519.1 ammonium transporter -
  LG36_RS08055 (LG36_1542) covS 1685807..1687282 (-) 1476 WP_038601520.1 HAMP domain-containing histidine kinase Regulator
  LG36_RS08060 (LG36_1543) covR 1687291..1687983 (-) 693 WP_038601521.1 response regulator transcription factor Regulator
  LG36_RS08065 (LG36_1544) - 1688139..1688669 (-) 531 WP_038601522.1 DUF177 domain-containing protein -
  LG36_RS08070 (LG36_1545) - 1688800..1689045 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  LG36_RS08075 (LG36_1546) - 1689202..1689666 (-) 465 WP_029344120.1 hypothetical protein -
  LG36_RS08080 (LG36_1547) - 1689748..1690110 (-) 363 WP_038601523.1 TIGR02328 family protein -
  LG36_RS08085 (LG36_1548) - 1690326..1691168 (-) 843 WP_038601524.1 metallophosphoesterase -
  LG36_RS08090 (LG36_1549) - 1691399..1691992 (-) 594 WP_038601525.1 TMEM175 family protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26700.36 Da        Isoelectric Point: 5.1273

>NTDB_id=129643 LG36_RS08060 WP_038601521.1 1687291..1687983(-) (covR) [Lactococcus lactis strain AI06]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEESTSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=129643 LG36_RS08060 WP_038601521.1 1687291..1687983(-) (covR) [Lactococcus lactis strain AI06]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCACGATTCGTCTCATTAGAATTGGAGCATGAAGG
CTATGCGACTGAGATTAAAGATAATGGACGCTCTGGTCTTGAAGAATCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGCAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGAGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCCAT
CGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAACATGGTCACGCCGTTGAGCGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACAAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTTCTTTTGACGTTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAGGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

99.565

100

0.996
  covR Streptococcus salivarius strain HSISS4

67.982

99.13

0.674
  vicR Streptococcus mutans UA159

45.887

100

0.461
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.435
  ciaR Streptococcus mutans UA159

37.168

98.261

0.365

Multiple sequence alignment