Detailed information NTG0129033

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LA24_RS02065
• Genome accession: NZ_CP009419
• Coordinates: 399537..400730 (+)
• Length: 397 a.a.
• NCBI ID: WP_002216225.1
• Uniprot ID: -
• Organism: Neisseria meningitidis M7124
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 394537..405730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA24_RS02050 (LA24_02140)	-	395460..396059 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
LA24_RS02055 (LA24_02145)	-	396059..398176 (+)	2118	WP_002247928.1	sensor histidine kinase	-
LA24_RS02060 (LA24_02150)	-	398169..399446 (+)	1278	WP_002247929.1	sigma-54-dependent transcriptional regulator	-
LA24_RS02065 (LA24_02155)	dprA	399537..400730 (+)	1194	WP_002216225.1	DNA-processing protein DprA	Machinery gene
LA24_RS02070 (LA24_02160)	-	400756..401217 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
LA24_RS02075 (LA24_02165)	topA	401289..403595 (+)	2307	WP_002224383.1	type I DNA topoisomerase	-
LA24_RS02080 (LA24_02170)	-	403668..404363 (-)	696	WP_002216227.1	hypothetical protein	-
LA24_RS02090 (LA24_02180)	-	405054..405431 (+)	378	WP_002247931.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42654.87 Da
• Isoelectric Point: 6.3983

>NTDB_id=129033 LA24_RS02065 WP_002216225.1 399537..400730(+) (dprA) [Neisseria meningitidis M7124]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVALAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAERGLIVSEFPLDTRPFAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPRLLQNEGASSYSINKGMPEKRITAVQT
ASDQLSLPEGKMPSEKTENRPVGGSILDRMGFDPVHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1194 bp

>NTDB_id=129033 LA24_RS02065 WP_002216225.1 399537..400730(+) (dprA) [Neisseria meningitidis M7124]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCTGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCCTCGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCCGTCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCGTTGCAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCTTATGAAATTGCCGAAAGGGGATTGATTGTCAGCGAGTTCCCTTTGGACACGCGTCCGTTTG
CAGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCACTGTCGCAAGTAACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGTTTGGCGGCAGAAATGGGGCGCGAGGTAATGGCGGTACCCGGTTCGATAGACAACCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGCCTGGACGACATCCTGAACGAATGCCCGC
GGCTCTTGCAAAATGAGGGTGCTTCGTCATATTCTATAAATAAGGGAATGCCTGAAAAGCGCATCACTGCCGTTCAGACG
GCATCCGACCAGCTGTCTCTGCCTGAAGGCAAAATGCCGTCTGAAAAGACGGAGAACCGACCCGTCGGCGGCAGTATCTT
GGACAGGATGGGTTTCGACCCAGTTCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCG
CACTGTTGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (344-390)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	94.962	100	0.95
dprA	Neisseria meningitidis MC58	94.962	100	0.95
dprA	Neisseria gonorrhoeae strain FA1090	89.421	100	0.894
dprA	Neisseria gonorrhoeae MS11	89.169	100	0.892
dprA	Vibrio cholerae strain A1552	37.845	100	0.38
dprA	Vibrio campbellii strain DS40M4	36.99	98.741	0.365