Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NJ8700_RS06730 Genome accession   NZ_CP009230
Coordinates   1471815..1473053 (+) Length   412 a.a.
NCBI ID   WP_005701265.1    Uniprot ID   -
Organism   Aggregatibacter aphrophilus NJ8700     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1466815..1478053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NJ8700_RS06710 (NJ8700_06870) nanQ 1468317..1468787 (+) 471 WP_005701260.1 N-acetylneuraminate anomerase -
  NJ8700_RS06715 (NJ8700_06875) ampD 1469260..1469814 (-) 555 WP_012771713.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  NJ8700_RS06720 (NJ8700_06880) pilA 1469939..1470388 (+) 450 WP_005701262.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  NJ8700_RS06725 (NJ8700_06885) pilB 1470413..1471822 (+) 1410 WP_005701263.1 GspE/PulE family protein Machinery gene
  NJ8700_RS06730 (NJ8700_06890) pilC 1471815..1473053 (+) 1239 WP_005701265.1 type II secretion system F family protein Machinery gene
  NJ8700_RS06735 (NJ8700_06895) - 1473050..1473742 (+) 693 WP_005701266.1 A24 family peptidase -
  NJ8700_RS06740 (NJ8700_06900) coaE 1473795..1474415 (+) 621 WP_005701267.1 dephospho-CoA kinase -
  NJ8700_RS06745 (NJ8700_06905) yacG 1474408..1474620 (+) 213 WP_005701268.1 DNA gyrase inhibitor YacG -
  NJ8700_RS06750 (NJ8700_06910) - 1474620..1474886 (+) 267 WP_005701270.1 GNAT family N-acetyltransferase -
  NJ8700_RS06755 (NJ8700_06915) - 1475253..1476626 (+) 1374 WP_005701272.1 sodium:alanine symporter family protein -
  NJ8700_RS06760 (NJ8700_06920) raiA 1476853..1477176 (+) 324 WP_005701273.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 46770.26 Da        Isoelectric Point: 10.2607

>NTDB_id=127407 NJ8700_RS06730 WP_005701265.1 1471815..1473053(+) (pilC) [Aggregatibacter aphrophilus NJ8700]
MRKLKLFNWHGVNRLQQKQKGTIVAESAVIAQQQLMSRGLQHIKLQQNWQLNSKPKNAEVCALLSQLATLLQAAVPLKNS
LQILLQHCTNIALNAWLRQLLKDIESGLAFSQALEKQNVEKQNQYLTYQDRQLIKVGEMTGKLPTVCHEIAQHKQQALAL
QRKIRKILLYPVLVLGISLILTALLLLFIVPQFAAMYDNSSAQLPTFTQVLLTLSQGLQDYWLHLLICLTLTILFIRARL
KHSPWFNRQKIRLINATPVLNHIVQLSRLVGFSRSLFLMLQAGVPLNQALQSFLPQNPSWQRSPNVQGDWLLIEEVQSIL
HWLQQGYAFSASVSSHIFPLAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDYQIDLLSQMLEPLLMVIIGGLIGLIMLGM
YLPIFNMGALVQ

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=127407 NJ8700_RS06730 WP_005701265.1 1471815..1473053(+) (pilC) [Aggregatibacter aphrophilus NJ8700]
ATGCGTAAACTGAAATTATTTAACTGGCACGGGGTTAACCGTCTACAGCAAAAGCAGAAAGGCACTATAGTGGCGGAAAG
CGCTGTAATAGCACAACAACAGCTGATGTCACGCGGTTTACAACACATTAAACTGCAACAAAATTGGCAATTAAACAGCA
AGCCTAAAAACGCCGAAGTCTGTGCGTTACTTTCTCAGCTGGCGACCTTATTACAAGCGGCGGTTCCGTTAAAAAATAGT
CTGCAAATTTTGTTACAACATTGCACCAATATTGCGCTAAACGCTTGGTTGCGCCAACTTTTAAAGGATATTGAAAGCGG
TTTGGCATTTTCCCAAGCCTTAGAAAAACAAAACGTAGAAAAACAAAATCAATATTTGACCTATCAAGATCGCCAATTAA
TTAAAGTCGGTGAAATGACGGGCAAGTTACCCACCGTGTGCCATGAAATCGCGCAACACAAACAGCAGGCATTGGCGTTG
CAACGGAAGATTCGAAAAATTCTGCTTTATCCGGTGTTGGTACTTGGCATATCGCTGATTTTAACCGCACTTTTACTGCT
GTTTATCGTGCCGCAATTCGCCGCGATGTATGACAATAGCAGCGCGCAACTCCCGACTTTCACCCAGGTGCTACTCACAC
TGTCGCAAGGATTACAGGATTATTGGCTGCATCTGTTAATTTGTCTTACGTTGACTATTCTGTTTATTCGCGCCCGCTTG
AAACATTCCCCTTGGTTTAATCGGCAAAAAATTCGATTAATCAATGCCACACCGGTGCTGAATCACATCGTGCAACTTTC
CCGTTTGGTGGGATTTAGCCGCAGTTTATTTTTAATGTTACAGGCGGGCGTGCCGCTGAATCAGGCTTTGCAGTCATTTT
TACCACAAAATCCAAGTTGGCAAAGATCGCCAAACGTGCAAGGCGATTGGCTGTTAATCGAAGAAGTTCAGTCCATTTTA
CACTGGCTACAACAAGGTTATGCCTTCTCCGCCAGTGTGAGTAGCCATATTTTTCCGTTGGCGGCACAACAAATGCTACA
AGTGGGCGAACAAAGTGGTCAGCTCCCCAAAATGTTGCAATTTATTGCCAACGACCATCAACAACAATTGGACTATCAGA
TCGATCTGCTGTCACAAATGTTGGAGCCGCTGTTGATGGTCATTATCGGTGGGCTTATCGGCTTAATTATGCTCGGGATG
TATTTGCCGATTTTCAATATGGGTGCGTTGGTGCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(272-403)

Type II secretion system (T2SS), protein F (T2SSF)

(64-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

60.539

99.029

0.6
  pilC Haemophilus influenzae 86-028NP

60.294

99.029

0.597
  pilC Glaesserella parasuis strain SC1401

40.049

100

0.4

Multiple sequence alignment