Detailed information NTG0126438

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: NCDO2118_RS09735
• Genome accession: NZ_CP009054
• Coordinates: 2015431..2017641 (-)
• Length: 736 a.a.
• NCBI ID: WP_012898341.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis NCDO 2118
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2010431..2022641

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NCDO2118_RS09705 (NCDO2118_1873)	atpA	2010473..2011975 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
NCDO2118_RS09710 (NCDO2118_1874)	-	2012162..2012689 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
NCDO2118_RS09715 (NCDO2118_1875)	atpF	2012691..2013197 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
NCDO2118_RS09720 (NCDO2118_1876)	atpB	2013212..2013925 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
NCDO2118_RS09725 (NCDO2118_1877)	-	2013970..2014185 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
NCDO2118_RS09730 (NCDO2118_1878)	-	2014370..2015146 (-)	777	WP_012898340.1	alpha/beta hydrolase	-
NCDO2118_RS09735 (NCDO2118_1879)	comEC	2015431..2017641 (-)	2211	WP_012898341.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NCDO2118_RS09740 (NCDO2118_1880)	comEA	2017622..2018269 (-)	648	WP_012898342.1	ComEA family DNA-binding protein	Machinery gene
NCDO2118_RS09745 (NCDO2118_1881)	-	2018329..2019690 (-)	1362	WP_012898343.1	ABC transporter permease	-
NCDO2118_RS09750 (NCDO2118_1882)	-	2019687..2020619 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
NCDO2118_RS09755 (NCDO2118_1883)	-	2020724..2021122 (-)	399	WP_004255236.1	hypothetical protein	-
NCDO2118_RS09760 (NCDO2118_1884)	-	2021231..2021794 (-)	564	WP_012898344.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84661.33 Da
• Isoelectric Point: 9.6248

>NTDB_id=126438 NCDO2118_RS09735 WP_012898341.1 2015431..2017641(-) (comEC) [Lactococcus lactis subsp. lactis NCDO 2118]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQMGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKEIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDEIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGKENRYGHPNQETLETFKKYQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=126438 NCDO2118_RS09735 WP_012898341.1 2015431..2017641(-) (comEC) [Lactococcus lactis subsp. lactis NCDO 2118]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCGGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAACCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATGGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCGT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGAAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGGGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAGATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAATTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATGAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTAAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAACCCCAAACTTGCCCTCATTTCGGTTGGCAAGGAAAATCGAT
ATGGACATCCCAACCAAGAAACTCTAGAAACTTTTAAAAAATACCAAATCAGAATACTTAGAACCGATCAAAAGGGAGCG
CTTAAATTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	77.038	100	0.77
comEC/celB	Streptococcus mitis SK321	44.609	100	0.45
comEC/celB	Streptococcus mitis NCTC 12261	44.474	100	0.448
comEC/celB	Streptococcus pneumoniae TIGR4	43.742	100	0.442
comEC/celB	Streptococcus pneumoniae Rx1	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae D39	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae R6	43.338	100	0.438