Detailed information NTG0126436

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: NCDO2118_RS09515
• Genome accession: NZ_CP009054
• Coordinates: 1969724..1970713 (-)
• Length: 329 a.a.
• NCBI ID: WP_012898311.1
• Uniprot ID: A0A0A7T187
• Organism: Lactococcus lactis subsp. lactis NCDO 2118
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1964724..1975713

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NCDO2118_RS09500 (NCDO2118_1833)	-	1966090..1967016 (-)	927	WP_010906107.1	peptidyl-prolyl cis-trans isomerase	-
NCDO2118_RS09505 (NCDO2118_1834)	-	1967170..1967853 (-)	684	WP_010906108.1	O-methyltransferase	-
NCDO2118_RS09510 (NCDO2118_1835)	pepF	1967856..1969661 (-)	1806	WP_038603683.1	oligoendopeptidase F	Regulator
NCDO2118_RS09515 (NCDO2118_1836)	coiA	1969724..1970713 (-)	990	WP_012898311.1	competence protein CoiA	Machinery gene
NCDO2118_RS09520 (NCDO2118_1837)	-	1970787..1971872 (-)	1086	WP_012898312.1	YdcF family protein	-
NCDO2118_RS09525 (NCDO2118_1838)	-	1972034..1972882 (-)	849	WP_012898313.1	alpha/beta hydrolase	-
NCDO2118_RS09530 (NCDO2118_1839)	-	1973074..1974495 (-)	1422	WP_012898314.1	NCS2 family permease	-
NCDO2118_RS09535 (NCDO2118_1840)	-	1974802..1975638 (+)	837	WP_003130402.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 39384.91 Da
• Isoelectric Point: 8.5207

>NTDB_id=126436 NCDO2118_RS09515 WP_012898311.1 1969724..1970713(-) (coiA) [Lactococcus lactis subsp. lactis NCDO 2118]
MLTAIDENGQVVNLLEIEVKELTGKYFCPSCKSELFIKNGEIKMTHFAHKSLKACDLWLENESEQHLGLKKALYQWFKKT
DKVEIEAYIPEFKQRPDLLVNDKIAIEIQCSHLSTKRLKERTENYQVHGFTVLWLMGQDLWLKEQITELQKNLVYFSENR
GFYYWELDFKAQKMRLKSLIHEDLRGKIIYLQEEIPFGEGRLIEQLRLPFLSQKLLTIPLIVDLKLAEFIRQQLYYCSPK
WLKLQEKYYQRGENLLNLTFERSFIAPLGLNLLEVFDDKIPLHKFTQIKQNINLYYENFLINFQQNSFKAVYPPRFYAIM
KKQKKDMNE

Nucleotide

• Length: 990 bp

>NTDB_id=126436 NCDO2118_RS09515 WP_012898311.1 1969724..1970713(-) (coiA) [Lactococcus lactis subsp. lactis NCDO 2118]
ATGTTGACAGCAATTGATGAAAATGGACAAGTAGTAAACTTATTAGAAATAGAAGTAAAAGAACTGACAGGAAAATATTT
TTGTCCTTCTTGTAAATCAGAGTTATTTATAAAAAATGGTGAAATAAAGATGACTCACTTTGCTCATAAATCTCTCAAAG
CTTGCGACTTATGGCTTGAAAACGAATCTGAACAACATTTAGGATTAAAAAAAGCACTCTATCAATGGTTTAAAAAAACT
GATAAGGTGGAAATTGAAGCTTATATTCCTGAATTTAAGCAGAGGCCAGATTTATTGGTAAATGATAAAATAGCTATTGA
AATTCAATGTTCTCATCTTTCTACGAAACGTTTAAAAGAAAGGACAGAGAATTATCAAGTCCACGGTTTTACGGTACTTT
GGCTTATGGGGCAAGATTTATGGTTAAAAGAGCAAATAACAGAACTTCAAAAAAATCTAGTCTATTTTTCAGAAAATAGA
GGTTTCTATTATTGGGAGTTAGATTTCAAAGCTCAGAAGATGAGATTAAAATCCCTGATTCATGAAGATTTGCGTGGAAA
AATTATTTATTTACAAGAAGAAATTCCTTTTGGGGAAGGACGACTTATTGAGCAATTACGACTGCCTTTTTTATCACAAA
AGTTACTGACAATACCACTTATTGTTGATCTTAAACTAGCAGAATTTATTCGTCAGCAACTTTATTATTGTTCACCAAAA
TGGTTGAAACTTCAGGAAAAATATTACCAAAGAGGTGAAAATTTGTTGAATTTGACTTTTGAACGTTCATTTATTGCTCC
TTTGGGATTGAACTTACTTGAAGTTTTTGATGATAAAATTCCTTTACATAAATTTACTCAAATTAAGCAGAATATTAATC
TTTATTATGAAAACTTTTTAATAAATTTTCAGCAAAATAGCTTTAAGGCAGTCTATCCTCCCCGTTTCTATGCTATAATG
AAAAAGCAGAAGAAGGATATGAATGAATGA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-266)

3D structure

• AlphaFold DB: A0A0A7T187

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Lactococcus lactis subsp. cremoris KW2	75.767	99.088	0.751
coiA	Streptococcus pneumoniae TIGR4	44.41	97.872	0.435
coiA	Streptococcus pneumoniae Rx1	44.41	97.872	0.435
coiA	Streptococcus pneumoniae D39	44.41	97.872	0.435
coiA	Streptococcus pneumoniae R6	44.41	97.872	0.435
coiA	Streptococcus mitis NCTC 12261	44.41	97.872	0.435